BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

528 related articles for article (PubMed ID: 23641925)

  • 21. Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease.
    Ciarlo L; Manganelli V; Matarrese P; Garofalo T; Tinari A; Gambardella L; Marconi M; Grasso M; Misasi R; Sorice M; Malorni W
    J Lipid Res; 2012 Oct; 53(10):2057-2068. PubMed ID: 22773688
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Effects of overexpression of huntingtin proteins on mitochondrial integrity.
    Wang H; Lim PJ; Karbowski M; Monteiro MJ
    Hum Mol Genet; 2009 Feb; 18(4):737-52. PubMed ID: 19039036
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Could successful (mitochondrial) networking help prevent Huntington's disease?
    Oliveira JM; Lightowlers RN
    EMBO Mol Med; 2010 Dec; 2(12):487-9. PubMed ID: 21117121
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli.
    Costa V; Giacomello M; Hudec R; Lopreiato R; Ermak G; Lim D; Malorni W; Davies KJ; Carafoli E; Scorrano L
    EMBO Mol Med; 2010 Dec; 2(12):490-503. PubMed ID: 21069748
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.
    Zhang H; Li Q; Graham RK; Slow E; Hayden MR; Bezprozvanny I
    Neurobiol Dis; 2008 Jul; 31(1):80-8. PubMed ID: 18502655
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability.
    Fu Z; Liu F; Liu C; Jin B; Jiang Y; Tang M; Qi X; Guo X
    Biochim Biophys Acta Mol Basis Dis; 2019 Jun; 1865(6):1428-1435. PubMed ID: 30802639
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis.
    Kim DI; Lee KH; Gabr AA; Choi GE; Kim JS; Ko SH; Han HJ
    Biochim Biophys Acta; 2016 Nov; 1863(11):2820-2834. PubMed ID: 27599716
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Nitric oxide links mitochondrial fission to Alzheimer's disease.
    Westermann B
    Sci Signal; 2009 May; 2(69):pe29. PubMed ID: 19417214
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
    Manczak M; Kandimalla R; Fry D; Sesaki H; Reddy PH
    Hum Mol Genet; 2016 Dec; 25(23):5148-5166. PubMed ID: 27677309
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
    Baek SH; Park SJ; Jeong JI; Kim SH; Han J; Kyung JW; Baik SH; Choi Y; Choi BY; Park JS; Bahn G; Shin JH; Jo DS; Lee JY; Jang CG; Arumugam TV; Kim J; Han JW; Koh JY; Cho DH; Jo DG
    J Neurosci; 2017 May; 37(20):5099-5110. PubMed ID: 28432138
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Inhibition of Drp1 hyperactivation reduces neuropathology and behavioral deficits in zQ175 knock-in mouse model of Huntington's disease.
    Zhao Y; Sun X; Qi X
    Biochem Biophys Res Commun; 2018 Dec; 507(1-4):319-323. PubMed ID: 30449600
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.
    Onur TS; Laitman A; Zhao H; Keyho R; Kim H; Wang J; Mair M; Wang H; Li L; Perez A; de Haro M; Wan YW; Allen G; Lu B; Al-Ramahi I; Liu Z; Botas J
    Elife; 2021 Apr; 10():. PubMed ID: 33871358
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mitochondrial fission in Huntington's disease mouse striatum disrupts ER-mitochondria contacts leading to disturbances in Ca
    Cherubini M; Lopez-Molina L; Gines S
    Neurobiol Dis; 2020 Mar; 136():104741. PubMed ID: 31931142
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.
    Yin X; Manczak M; Reddy PH
    Hum Mol Genet; 2016 May; 25(9):1739-53. PubMed ID: 26908605
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mitochondrial Abnormalities and Synaptic Damage in Huntington's Disease: a Focus on Defective Mitophagy and Mitochondria-Targeted Therapeutics.
    Sawant N; Morton H; Kshirsagar S; Reddy AP; Reddy PH
    Mol Neurobiol; 2021 Dec; 58(12):6350-6377. PubMed ID: 34519969
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
    Wang X; Su B; Lee HG; Li X; Perry G; Smith MA; Zhu X
    J Neurosci; 2009 Jul; 29(28):9090-103. PubMed ID: 19605646
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice.
    Yang X; Wang H; Ni HM; Xiong A; Wang Z; Sesaki H; Ding WX; Yang L
    Redox Biol; 2017 Aug; 12():264-273. PubMed ID: 28282614
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease.
    Yu ZX; Li SH; Evans J; Pillarisetti A; Li H; Li XJ
    J Neurosci; 2003 Mar; 23(6):2193-202. PubMed ID: 12657678
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dynamin-related protein 1: A critical protein in the pathogenesis of neural system dysfunctions and neurodegenerative diseases.
    Qi Z; Huang Z; Xie F; Chen L
    J Cell Physiol; 2019 Jul; 234(7):10032-10046. PubMed ID: 30515821
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synaptic RTP801 contributes to motor-learning dysfunction in Huntington's disease.
    Martín-Flores N; Pérez-Sisqués L; Creus-Muncunill J; Masana M; Ginés S; Alberch J; Pérez-Navarro E; Malagelada C
    Cell Death Dis; 2020 Jul; 11(7):569. PubMed ID: 32732871
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 27.