152 related articles for article (PubMed ID: 23644977)
1. C-5 hydroxyethyl and hydroxypropyl acyclonucleosides as substrates for thymidine kinase of herpes simplex virus type 1 (HSV-1 TK): syntheses and biological evaluation.
Meščić A; Krištafor S; Novaković I; Osmanović A; Müller U; Završnik D; Ametamey SM; Scapozza L; Raić-Malić S
Molecules; 2013 May; 18(5):5104-24. PubMed ID: 23644977
[TBL] [Abstract][Full Text] [Related]
2. Fluorosubstitution and 7-alkylation as prospective modifications of biologically active 6-aryl derivatives of tricyclic acyclovir and ganciclovir analogues.
Ostrowski T; Golankiewicz B; De Clercq E; Balzarini J
Bioorg Med Chem; 2005 Mar; 13(6):2089-96. PubMed ID: 15727862
[TBL] [Abstract][Full Text] [Related]
3. The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.
Balzarini J; Liekens S; Esnouf R; De Clercq E
Biochemistry; 2002 May; 41(20):6517-24. PubMed ID: 12009916
[TBL] [Abstract][Full Text] [Related]
4. Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.
Focher F; Lossani A; Verri A; Spadari S; Maioli A; Gambino JJ; Wright GE; Eberle R; Black DH; Medveczky P; Medveczky M; Shugar D
Antimicrob Agents Chemother; 2007 Jun; 51(6):2028-34. PubMed ID: 17438061
[TBL] [Abstract][Full Text] [Related]
5. A new nucleoside analogue with potent activity against mutant sr39 herpes simplex virus-1 (HSV-1) thymidine kinase (TK).
Sundaram GS; Harpstrite SE; Kao JL; Collins SD; Sharma V
Org Lett; 2012 Jul; 14(14):3568-71. PubMed ID: 22765027
[TBL] [Abstract][Full Text] [Related]
6. A new acycloguanosine-specific supermutant of herpes simplex virus type 1 thymidine kinase suitable for PET imaging and suicide gene therapy for potential use in patients treated with pyrimidine-based cytotoxic drugs.
Likar Y; Dobrenkov K; Olszewska M; Vider E; Shenker L; Cai S; Pillarsetty N; Hricak H; Ponomarev V
J Nucl Med; 2008 May; 49(5):713-20. PubMed ID: 18413388
[TBL] [Abstract][Full Text] [Related]
7. Synthesis, 18F-radiolabelling and biological evaluations of C-6 alkylated pyrimidine nucleoside analogues.
Raić-Malić S; Johayem A; Ametamey SM; Batinac S; De Clercq E; Folkers G; Scapozza L
Nucleosides Nucleotides Nucleic Acids; 2004; 23(11):1707-21. PubMed ID: 15598073
[TBL] [Abstract][Full Text] [Related]
8. Modifications on the heterocyclic base of ganciclovir, penciclovir, acyclovir - syntheses and antiviral properties.
Chuchkov K; Chayrov R; Hinkov A; Todorov D; Shishkova K; Stankova IG
Nucleosides Nucleotides Nucleic Acids; 2020; 39(7):979-990. PubMed ID: 32312162
[TBL] [Abstract][Full Text] [Related]
9. A new N-methyl thymine derivative comprising a dihydroxyisobutenyl unit as ligand for thymidine kinase of herpes simplex virus type 1 (HSV-1 TK).
Krištafor S; Novaković I; Gazivoda Kraljević T; Kraljević Pavelić S; Lučin P; Westermaier Y; Pernot L; Scapozza L; Ametamey SM; Raić-Malić S
Bioorg Med Chem Lett; 2011 Oct; 21(20):6161-5. PubMed ID: 21911293
[TBL] [Abstract][Full Text] [Related]
10. Selective abolishment of pyrimidine nucleoside kinase activity of herpes simplex virus type 1 thymidine kinase by mutation of alanine-167 to tyrosine.
Degrève B; Esnouf R; De Clercq E; Balzarini J
Mol Pharmacol; 2000 Dec; 58(6):1326-32. PubMed ID: 11093770
[TBL] [Abstract][Full Text] [Related]
11. Testing the sensitivities of noncognate inhibitors to varicella zoster virus thymidine kinase: implications for postherpetic neuralgia therapy with existing agents.
Yang L; Mo X; Yang H; Dai H; Tan F
J Mol Model; 2014 Jul; 20(7):2321. PubMed ID: 24961898
[TBL] [Abstract][Full Text] [Related]
12. Intracellular uptake of thymidine and antiherpetic drugs for thymidine kinase-deficient mutants of herpes simplex virus type 1.
Bae PK; Kim JH; Kim HS; Chung IK; Paik SG; Lee CK
Antiviral Res; 2006 Jul; 70(3):93-104. PubMed ID: 16546268
[TBL] [Abstract][Full Text] [Related]
13. Engineering of a single conserved amino acid residue of herpes simplex virus type 1 thymidine kinase allows a predominant shift from pyrimidine to purine nucleoside phosphorylation.
Balzarini J; Liekens S; Solaroli N; El Omari K; Stammers DK; Karlsson A
J Biol Chem; 2006 Jul; 281(28):19273-9. PubMed ID: 16702226
[TBL] [Abstract][Full Text] [Related]
14. The Epstein-Barr virus thymidine kinase does not phosphorylate ganciclovir or acyclovir and demonstrates a narrow substrate specificity compared to the herpes simplex virus type 1 thymidine kinase.
Gustafson EA; Chillemi AC; Sage DR; Fingeroth JD
Antimicrob Agents Chemother; 1998 Nov; 42(11):2923-31. PubMed ID: 9797227
[TBL] [Abstract][Full Text] [Related]
15. Evaluation of scopadulciol-related molecules for their stimulatory effect on the cytotoxicity of acyclovir and ganciclovir against Herpes simplex virus type 1 thymidine kinase gene-transfected HeLa cells.
Hayashi K; Rahman SM; Ohno H; Tanaka T; Toyooka N; Nemoto H; Hayashi T
Chem Pharm Bull (Tokyo); 2004 Aug; 52(8):1015-7. PubMed ID: 15305006
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives.
Mohammed AF; Andrei G; Hayallah AM; Abdel-Moty SG; Snoeck R; Simons C
Bioorg Med Chem; 2019 Mar; 27(6):1023-1033. PubMed ID: 30738653
[TBL] [Abstract][Full Text] [Related]
17. Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.
Degrève B; Esnouf R; De Clercq E; Balzarini J
Mol Pharmacol; 2001 Feb; 59(2):285-93. PubMed ID: 11160865
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and antiviral activity of 3-substituted derivatives of 3,9-dihydro-9-oxo-5H-imidazo[1,2-a]purines, tricyclic analogues of acyclovir and ganciclovir.
Boryski J; Golankiewicz B; De Clercq E
J Med Chem; 1991 Aug; 34(8):2380-3. PubMed ID: 1652016
[TBL] [Abstract][Full Text] [Related]
19. Characterization of herpes simplex viruses selected in culture for resistance to penciclovir or acyclovir.
Sarisky RT; Quail MR; Clark PE; Nguyen TT; Halsey WS; Wittrock RJ; O'Leary Bartus J; Van Horn MM; Sathe GM; Van Horn S; Kelly MD; Bacon TH; Leary JJ
J Virol; 2001 Feb; 75(4):1761-9. PubMed ID: 11160674
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and fluorescent properties of 6-(4-biphenylyl)-3,9-dihydro-9-oxo-5H-imidazo[1,2-a]purine analogues of acyclovir and ganciclovir.
Goslinski T; Wenska G; Golankiewicz B; Balzarini J; De Clercq E
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):911-4. PubMed ID: 14565309
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
