BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

429 related articles for article (PubMed ID: 23651073)

  • 1. A comparison of two strategies for affinity maturation of a BH3 peptide toward pro-survival Bcl-2 proteins.
    Zhang S; Long A; Link AJ
    ACS Synth Biol; 2012 Mar; 1(3):89-98. PubMed ID: 23651073
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Relationship between helix stability and binding affinities: molecular dynamics simulations of Bfl-1/A1-binding pro-apoptotic BH3 peptide helices in explicit solvent.
    Modi V; Lama D; Sankararamakrishnan R
    J Biomol Struct Dyn; 2013; 31(1):65-77. PubMed ID: 22803956
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anti-apoptotic Bcl-XL protein in complex with BH3 peptides of pro-apoptotic Bak, Bad, and Bim proteins: comparative molecular dynamics simulations.
    Lama D; Sankararamakrishnan R
    Proteins; 2008 Nov; 73(2):492-514. PubMed ID: 18452209
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuclear magnetic resonance study of protein-protein interactions involving apoptosis regulator Diva (Boo) and the BH3 domain of proapoptotic Bcl-2 members.
    Santiveri CM; Sborgi L; de Alba E
    J Mol Recognit; 2012 Dec; 25(12):665-73. PubMed ID: 23192964
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and helical structure of lactam bridged BH3 peptides derived from pro-apoptotic Bcl-2 family proteins.
    Yang B; Liu D; Huang Z
    Bioorg Med Chem Lett; 2004 Mar; 14(6):1403-6. PubMed ID: 15006371
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
    Kuwana T; Bouchier-Hayes L; Chipuk JE; Bonzon C; Sullivan BA; Green DR; Newmeyer DD
    Mol Cell; 2005 Feb; 17(4):525-35. PubMed ID: 15721256
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions.
    Finnegan NM; Curtin JF; Prevost G; Morgan B; Cotter TG
    Br J Cancer; 2001 Jul; 85(1):115-21. PubMed ID: 11437412
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.
    Chen L; Willis SN; Wei A; Smith BJ; Fletcher JI; Hinds MG; Colman PM; Day CL; Adams JM; Huang DC
    Mol Cell; 2005 Feb; 17(3):393-403. PubMed ID: 15694340
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X(L).
    Lama D; Sankararamakrishnan R
    J Comput Aided Mol Des; 2011 May; 25(5):413-26. PubMed ID: 21523491
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural biology of the Bcl-2 family of proteins.
    Petros AM; Olejniczak ET; Fesik SW
    Biochim Biophys Acta; 2004 Mar; 1644(2-3):83-94. PubMed ID: 14996493
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.
    Uren RT; Dewson G; Chen L; Coyne SC; Huang DC; Adams JM; Kluck RM
    J Cell Biol; 2007 Apr; 177(2):277-87. PubMed ID: 17452531
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Membrane-insertion fragments of Bcl-xL, Bax, and Bid.
    García-Sáez AJ; Mingarro I; Pérez-Payá E; Salgado J
    Biochemistry; 2004 Aug; 43(34):10930-43. PubMed ID: 15323553
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands.
    Kvansakul M; Yang H; Fairlie WD; Czabotar PE; Fischer SF; Perugini MA; Huang DC; Colman PM
    Cell Death Differ; 2008 Oct; 15(10):1564-71. PubMed ID: 18551131
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of the anti-apoptotic mechanism of Bcl-B.
    Zhai D; Ke N; Zhang H; Ladror U; Joseph M; Eichinger A; Godzik A; Ng SC; Reed JC
    Biochem J; 2003 Nov; 376(Pt 1):229-36. PubMed ID: 12921534
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Peptide screening to knockdown Bcl-2's anti-apoptotic activity: implications in cancer treatment.
    Raghav PK; Verma YK; Gangenahalli GU
    Int J Biol Macromol; 2012 Apr; 50(3):796-814. PubMed ID: 22155216
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.
    Willis SN; Chen L; Dewson G; Wei A; Naik E; Fletcher JI; Adams JM; Huang DC
    Genes Dev; 2005 Jun; 19(11):1294-305. PubMed ID: 15901672
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL.
    Yin H; Lee GI; Sedey KA; Kutzki O; Park HS; Orner BP; Ernst JT; Wang HG; Sebti SM; Hamilton AD
    J Am Chem Soc; 2005 Jul; 127(29):10191-6. PubMed ID: 16028929
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interaction of E1B 19K with Bax is required to block Bax-induced loss of mitochondrial membrane potential and apoptosis.
    Han J; Modha D; White E
    Oncogene; 1998 Dec; 17(23):2993-3005. PubMed ID: 9881701
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Binding affinity of pro-apoptotic BH3 peptides for the anti-apoptotic Mcl-1 and A1 proteins: Molecular dynamics simulations of Mcl-1 and A1 in complex with six different BH3 peptides.
    Modi V; Sankararamakrishnan R
    J Mol Graph Model; 2017 May; 73():115-128. PubMed ID: 28279820
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1.
    Day CL; Smits C; Fan FC; Lee EF; Fairlie WD; Hinds MG
    J Mol Biol; 2008 Jul; 380(5):958-71. PubMed ID: 18589438
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.