BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 23652018)

  • 1. GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy.
    Singh SK; Maeda K; Eid MM; Almofty SA; Ono M; Pham P; Goodman MF; Sakaguchi N
    Nat Commun; 2013; 4():1830. PubMed ID: 23652018
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA.
    Maeda K; Singh SK; Eda K; Kitabatake M; Pham P; Goodman MF; Sakaguchi N
    J Biol Chem; 2010 Jul; 285(31):23945-53. PubMed ID: 20507984
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Integrity of immunoglobulin variable regions is supported by GANP during AID-induced somatic hypermutation in germinal center B cells.
    Eid MMA; Shimoda M; Singh SK; Almofty SA; Pham P; Goodman MF; Maeda K; Sakaguchi N
    Int Immunol; 2017 May; 29(5):211-220. PubMed ID: 28541550
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Germinal Center B-Cell-Associated Nuclear Protein (GANP) Involved in RNA Metabolism for B Cell Maturation.
    Sakaguchi N; Maeda K
    Adv Immunol; 2016; 131():135-86. PubMed ID: 27235683
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GANP regulates the choice of DNA repair pathway by DNA-PKcs interaction in AID-dependent IgV region diversification.
    Eid MM; Maeda K; Almofty SA; Singh SK; Shimoda M; Sakaguchi N
    J Immunol; 2014 Jun; 192(12):5529-39. PubMed ID: 24808370
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular mechanism of immunoglobulin V-region diversification regulated by transcription and RNA metabolism in antigen-driven B cells.
    Sakaguchi N; Maeda K; Kuwahara K
    Scand J Immunol; 2011 Jun; 73(6):520-6. PubMed ID: 21388430
    [TBL] [Abstract][Full Text] [Related]  

  • 7. AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells.
    Gramlich HS; Reisbig T; Schatz DG
    PLoS One; 2012; 7(6):e39601. PubMed ID: 22768095
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo-activated cells.
    Maul RW; Cao Z; Venkataraman L; Giorgetti CA; Press JL; Denizot Y; Du H; Sen R; Gearhart PJ
    J Exp Med; 2014 Oct; 211(11):2297-306. PubMed ID: 25288395
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Germinal center-associated nuclear protein (GANP) has a phosphorylation-dependent DNA-primase activity that is up-regulated in germinal center regions.
    Kuwahara K; Tomiyasu S; Fujimura S; Nomura K; Xing Y; Nishiyama N; Ogawa M; Imajoh-Ohmi S; Izuta S; Sakaguchi N
    Proc Natl Acad Sci U S A; 2001 Aug; 98(18):10279-83. PubMed ID: 11526238
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cutting edge: double-stranded DNA breaks in the IgV region gene were detected at lower frequency in affinity-maturation impeded GANP-/- mice.
    Kawatani Y; Igarashi H; Matsui T; Kuwahara K; Fujimura S; Okamoto N; Takagi K; Sakaguchi N
    J Immunol; 2005 Nov; 175(9):5615-8. PubMed ID: 16237049
    [TBL] [Abstract][Full Text] [Related]  

  • 11. mRNA export from mammalian cell nuclei is dependent on GANP.
    Wickramasinghe VO; McMurtrie PI; Mills AD; Takei Y; Penrhyn-Lowe S; Amagase Y; Main S; Marr J; Stewart M; Laskey RA
    Curr Biol; 2010 Jan; 20(1):25-31. PubMed ID: 20005110
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cholangiocarcinomas associated with long-term inflammation express the activation-induced cytidine deaminase and germinal center-associated nuclear protein involved in immunoglobulin V-region diversification.
    Chan-On W; Kuwahara K; Kobayashi N; Ohta K; Shimasaki T; Sripa B; Leelayuwat C; Sakaguchi N
    Int J Oncol; 2009 Aug; 35(2):287-95. PubMed ID: 19578742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nucleosome stability dramatically impacts the targeting of somatic hypermutation.
    Kodgire P; Mukkawar P; North JA; Poirier MG; Storb U
    Mol Cell Biol; 2012 May; 32(10):2030-40. PubMed ID: 22393257
    [TBL] [Abstract][Full Text] [Related]  

  • 14. What Targets Somatic Hypermutation to the Immunoglobulin Loci?
    Heltzel JMH; Gearhart PJ
    Viral Immunol; 2020 May; 33(4):277-281. PubMed ID: 31770070
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching.
    Hu Y; Ericsson I; Torseth K; Methot SP; Sundheim O; Liabakk NB; Slupphaug G; Di Noia JM; Krokan HE; Kavli B
    J Mol Biol; 2013 Jan; 425(2):424-43. PubMed ID: 23183374
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Topoisomerase I deficiency causes RNA polymerase II accumulation and increases AID abundance in immunoglobulin variable genes.
    Maul RW; Saribasak H; Cao Z; Gearhart PJ
    DNA Repair (Amst); 2015 Jun; 30():46-52. PubMed ID: 25869824
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Replication protein A interacts with AID to promote deamination of somatic hypermutation targets.
    Chaudhuri J; Khuong C; Alt FW
    Nature; 2004 Aug; 430(7003):992-8. PubMed ID: 15273694
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export.
    Jani D; Lutz S; Hurt E; Laskey RA; Stewart M; Wickramasinghe VO
    Nucleic Acids Res; 2012 May; 40(10):4562-73. PubMed ID: 22307388
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription.
    Shen HM; Poirier MG; Allen MJ; North J; Lal R; Widom J; Storb U
    J Exp Med; 2009 May; 206(5):1057-71. PubMed ID: 19380635
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells.
    Rouaud P; Vincent-Fabert C; Saintamand A; Fiancette R; Marquet M; Robert I; Reina-San-Martin B; Pinaud E; Cogné M; Denizot Y
    J Exp Med; 2013 Jul; 210(8):1501-7. PubMed ID: 23825188
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.