BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 23658701)

  • 1. Critical role of a survivin/TGF-β/mTORC1 axis in IGF-I-mediated growth of prostate epithelial cells.
    Song K; Shankar E; Yang J; Bane KL; Wahdan-Alaswad R; Danielpour D
    PLoS One; 2013; 8(5):e61896. PubMed ID: 23658701
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
    Song K; Cornelius SC; Reiss M; Danielpour D
    J Biol Chem; 2003 Oct; 278(40):38342-51. PubMed ID: 12876289
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin-like growth factor I suppresses bone morphogenetic protein signaling in prostate cancer cells by activating mTOR signaling.
    Wahdan-Alaswad RS; Song K; Krebs TL; Shola DT; Gomez JA; Matsuyama S; Danielpour D
    Cancer Res; 2010 Nov; 70(22):9106-17. PubMed ID: 21062988
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rb/E2F4 and Smad2/3 link survivin to TGF-beta-induced apoptosis and tumor progression.
    Yang J; Song K; Krebs TL; Jackson MW; Danielpour D
    Oncogene; 2008 Sep; 27(40):5326-38. PubMed ID: 18504435
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation.
    Roca H; Varsos Z; Pienta KJ
    J Biol Chem; 2008 Sep; 283(36):25057-73. PubMed ID: 18611860
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2.
    Soares HP; Ming M; Mellon M; Young SH; Han L; Sinnet-Smith J; Rozengurt E
    Mol Cancer Ther; 2015 Apr; 14(4):1014-23. PubMed ID: 25673820
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transforming Growth Factor β1-induced Apoptosis in Podocytes via the Extracellular Signal-regulated Kinase-Mammalian Target of Rapamycin Complex 1-NADPH Oxidase 4 Axis.
    Das R; Xu S; Nguyen TT; Quan X; Choi SK; Kim SJ; Lee EY; Cha SK; Park KS
    J Biol Chem; 2015 Dec; 290(52):30830-42. PubMed ID: 26565025
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin-like growth factor-I receptor signaling pathway induces resistance to the apoptotic activities of SCH66336 (lonafarnib) through Akt/mammalian target of rapamycin-mediated increases in survivin expression.
    Oh SH; Jin Q; Kim ES; Khuri FR; Lee HY
    Clin Cancer Res; 2008 Mar; 14(5):1581-9. PubMed ID: 18316583
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of survivin expression by IGF-1/mTOR signaling.
    Vaira V; Lee CW; Goel HL; Bosari S; Languino LR; Altieri DC
    Oncogene; 2007 Apr; 26(19):2678-84. PubMed ID: 17072337
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta.
    Rahimi RA; Andrianifahanana M; Wilkes MC; Edens M; Kottom TJ; Blenis J; Leof EB
    Cancer Res; 2009 Jan; 69(1):84-93. PubMed ID: 19117990
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TGF-β effects on prostate cancer cell migration and invasion are mediated by PGE2 through activation of PI3K/AKT/mTOR pathway.
    Vo BT; Morton D; Komaragiri S; Millena AC; Leath C; Khan SA
    Endocrinology; 2013 May; 154(5):1768-79. PubMed ID: 23515290
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SOX2 promotes tumor growth of esophageal squamous cell carcinoma through the AKT/mammalian target of rapamycin complex 1 signaling pathway.
    Gen Y; Yasui K; Nishikawa T; Yoshikawa T
    Cancer Sci; 2013 Jul; 104(7):810-6. PubMed ID: 23510069
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activated phosphatidylinositol 3-kinase/Akt inhibits the transition of endothelial progenitor cells to mesenchymal cells by regulating the forkhead box subgroup O-3a signaling.
    Zhang Z; Zhang T; Zhou Y; Wei X; Zhu J; Zhang J; Wang C
    Cell Physiol Biochem; 2015; 35(4):1643-53. PubMed ID: 25824462
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anti-myeloma activity of Akt inhibition is linked to the activation status of PI3K/Akt and MEK/ERK pathway.
    Ramakrishnan V; Kimlinger T; Haug J; Painuly U; Wellik L; Halling T; Rajkumar SV; Kumar S
    PLoS One; 2012; 7(11):e50005. PubMed ID: 23185517
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway in acute lymphoblastic leukemia.
    Badura S; Tesanovic T; Pfeifer H; Wystub S; Nijmeijer BA; Liebermann M; Falkenburg JH; Ruthardt M; Ottmann OG
    PLoS One; 2013; 8(11):e80070. PubMed ID: 24244612
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Calpain-2 activates Akt via TGF-β1-mTORC2 pathway in pulmonary artery smooth muscle cells.
    Abeyrathna P; Kovacs L; Han W; Su Y
    Am J Physiol Cell Physiol; 2016 Jul; 311(1):C24-34. PubMed ID: 27099352
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CCL2 is a negative regulator of AMP-activated protein kinase to sustain mTOR complex-1 activation, survivin expression, and cell survival in human prostate cancer PC3 cells.
    Roca H; Varsos ZS; Pienta KJ
    Neoplasia; 2009 Dec; 11(12):1309-17. PubMed ID: 20019839
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.
    Yuen HF; Chan KK; Grills C; Murray JT; Platt-Higgins A; Eldin OS; O'Byrne K; Janne P; Fennell DA; Johnston PG; Rudland PS; El-Tanani M
    Clin Cancer Res; 2012 Jan; 18(2):380-91. PubMed ID: 22090358
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Feedback loops blockade potentiates apoptosis induction and antitumor activity of a novel AKT inhibitor DC120 in human liver cancer.
    Yang F; Deng R; Qian XJ; Chang SH; Wu XQ; Qin J; Feng GK; Ding K; Zhu XF
    Cell Death Dis; 2014 Mar; 5(3):e1114. PubMed ID: 24625973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A critical role for the mTORC2 pathway in lung fibrosis.
    Chang W; Wei K; Ho L; Berry GJ; Jacobs SS; Chang CH; Rosen GD
    PLoS One; 2014; 9(8):e106155. PubMed ID: 25162417
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.