BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 23658800)

  • 1. Effects of targeted suppression of glutaryl-CoA dehydrogenase by lentivirus-mediated shRNA and excessive intake of lysine on apoptosis in rat striatal neurons.
    Gao J; Zhang C; Fu X; Yi Q; Tian F; Ning Q; Luo X
    PLoS One; 2013; 8(5):e63084. PubMed ID: 23658800
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Effect of glutaryl-CoA dehydrogenase gene silencing and high-concentration lysine on the viability of BRL hepatocytes].
    Gao JZ; Zhang C; Yi Q; Ying YQ; Luo XP
    Zhongguo Dang Dai Er Ke Za Zhi; 2017 Sep; 19(9):1014-1019. PubMed ID: 28899474
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanistic effects of amino acids and glucose in a novel glutaric aciduria type 1 cell model.
    Fu X; Gao H; Tian F; Gao J; Lou L; Liang Y; Ning Q; Luo X
    PLoS One; 2014; 9(10):e110181. PubMed ID: 25333616
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The first knock-in rat model for glutaric aciduria type I allows further insights into pathophysiology in brain and periphery.
    Gonzalez Melo M; Remacle N; Cudré-Cung HP; Roux C; Poms M; Cudalbu C; Barroso M; Gersting SW; Feichtinger RG; Mayr JA; Costanzo M; Caterino M; Ruoppolo M; Rüfenacht V; Häberle J; Braissant O; Ballhausen D
    Mol Genet Metab; 2021 Jun; 133(2):157-181. PubMed ID: 33965309
    [TBL] [Abstract][Full Text] [Related]  

  • 5. l-Carnitine prevents oxidative stress in striatum of glutaryl-CoA dehydrogenase deficient mice submitted to lysine overload.
    Guerreiro G; Amaral AU; Ribeiro RT; Faverzani J; Groehs AC; Sitta A; Deon M; Wajner M; Vargas CR
    Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2420-2427. PubMed ID: 31181292
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Striatal neuronal death mediated by astrocytes from the Gcdh-/- mouse model of glutaric acidemia type I.
    Olivera-Bravo S; Ribeiro CA; Isasi E; Trías E; Leipnitz G; Díaz-Amarilla P; Woontner M; Beck C; Goodman SI; Souza D; Wajner M; Barbeito L
    Hum Mol Genet; 2015 Aug; 24(16):4504-15. PubMed ID: 25968119
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oxidative Stress, Disrupted Energy Metabolism, and Altered Signaling Pathways in Glutaryl-CoA Dehydrogenase Knockout Mice: Potential Implications of Quinolinic Acid Toxicity in the Neuropathology of Glutaric Acidemia Type I.
    Seminotti B; Amaral AU; Ribeiro RT; Rodrigues MDN; Colín-González AL; Leipnitz G; Santamaría A; Wajner M
    Mol Neurobiol; 2016 Nov; 53(9):6459-6475. PubMed ID: 26607633
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism.
    Biagosch C; Ediga RD; Hensler SV; Faerberboeck M; Kuehn R; Wurst W; Meitinger T; Kölker S; Sauer S; Prokisch H
    Biochim Biophys Acta Mol Basis Dis; 2017 Sep; 1863(9):2220-2228. PubMed ID: 28545977
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multifactorial modulation of susceptibility to l-lysine in an animal model of glutaric aciduria type I.
    Sauer SW; Opp S; Komatsuzaki S; Blank AE; Mittelbronn M; Burgard P; Koeller DM; Okun JG; Kölker S
    Biochim Biophys Acta; 2015 May; 1852(5):768-77. PubMed ID: 25558815
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Higher Vulnerability of Menadione-Exposed Cortical Astrocytes of Glutaryl-CoA Dehydrogenase Deficient Mice to Oxidative Stress, Mitochondrial Dysfunction, and Cell Death: Implications for the Neurodegeneration in Glutaric Aciduria Type I.
    Rodrigues MDN; Seminotti B; Zanatta Â; de Mello Gonçalves A; Bellaver B; Amaral AU; Quincozes-Santos A; Goodman SI; Woontner M; Souza DO; Wajner M
    Mol Neurobiol; 2017 Aug; 54(6):4795-4805. PubMed ID: 27510504
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acute renal proximal tubule alterations during induced metabolic crises in a mouse model of glutaric aciduria type 1.
    Thies B; Meyer-Schwesinger C; Lamp J; Schweizer M; Koeller DM; Ullrich K; Braulke T; Mühlhausen C
    Biochim Biophys Acta; 2013 Oct; 1832(10):1463-72. PubMed ID: 23623985
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interaction of glutaric aciduria type 1-related glutaryl-CoA dehydrogenase with mitochondrial matrix proteins.
    Schmiesing J; Schlüter H; Ullrich K; Braulke T; Mühlhausen C
    PLoS One; 2014; 9(2):e87715. PubMed ID: 24498361
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of Neuroinflammatory Response and Histopathological Alterations Caused by Quinolinic Acid Administration in the Striatum of Glutaryl-CoA Dehydrogenase Deficient Mice.
    Amaral AU; Seminotti B; da Silva JC; de Oliveira FH; Ribeiro RT; Vargas CR; Leipnitz G; Santamaría A; Souza DO; Wajner M
    Neurotox Res; 2018 Apr; 33(3):593-606. PubMed ID: 29235064
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased glutamate receptor and transporter expression in the cerebral cortex and striatum of gcdh-/- mice: possible implications for the neuropathology of glutaric acidemia type I.
    Lagranha VL; Matte U; de Carvalho TG; Seminotti B; Pereira CC; Koeller DM; Woontner M; Goodman SI; de Souza DO; Wajner M
    PLoS One; 2014; 9(3):e90477. PubMed ID: 24594605
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glutaric aciduria type 1 metabolites impair the succinate transport from astrocytic to neuronal cells.
    Lamp J; Keyser B; Koeller DM; Ullrich K; Braulke T; Mühlhausen C
    J Biol Chem; 2011 May; 286(20):17777-84. PubMed ID: 21454630
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Subependymal mass lesions and peripheral polyneuropathy in adult-onset glutaric aciduria type I.
    Herskovitz M; Goldsher D; Sela BA; Mandel H
    Neurology; 2013 Aug; 81(9):849-50. PubMed ID: 23884036
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Experimental evidence that bioenergetics disruption is not mainly involved in the brain injury of glutaryl-CoA dehydrogenase deficient mice submitted to lysine overload.
    Amaral AU; Cecatto C; Seminotti B; Ribeiro CA; Lagranha VL; Pereira CC; de Oliveira FH; de Souza DG; Goodman S; Woontner M; Wajner M
    Brain Res; 2015 Sep; 1620():116-29. PubMed ID: 25998543
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disease-causing mutations affecting surface residues of mitochondrial glutaryl-CoA dehydrogenase impair stability, heteromeric complex formation and mitochondria architecture.
    Schmiesing J; Lohmöller B; Schweizer M; Tidow H; Gersting SW; Muntau AC; Braulke T; Mühlhausen C
    Hum Mol Genet; 2017 Feb; 26(3):538-551. PubMed ID: 28062662
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deletion of 2-aminoadipic semialdehyde synthase limits metabolite accumulation in cell and mouse models for glutaric aciduria type 1.
    Leandro J; Dodatko T; DeVita RJ; Chen H; Stauffer B; Yu C; Houten SM
    J Inherit Metab Dis; 2020 Nov; 43(6):1154-1164. PubMed ID: 32567100
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inherited Disorders of Lysine Metabolism: A Review.
    Bouchereau J; Schiff M
    J Nutr; 2020 Oct; 150(Suppl 1):2556S-2560S. PubMed ID: 33000154
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.