BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 23665031)

  • 1. Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation.
    Wu G; Peng JB
    FEBS Lett; 2013 Jun; 587(12):1717-22. PubMed ID: 23665031
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.
    Ohta A; Schumacher FR; Mehellou Y; Johnson C; Knebel A; Macartney TJ; Wood NT; Alessi DR; Kurz T
    Biochem J; 2013 Apr; 451(1):111-22. PubMed ID: 23387299
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4.
    Shibata S; Zhang J; Puthumana J; Stone KL; Lifton RP
    Proc Natl Acad Sci U S A; 2013 May; 110(19):7838-43. PubMed ID: 23576762
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.
    Susa K; Sohara E; Rai T; Zeniya M; Mori Y; Mori T; Chiga M; Nomura N; Nishida H; Takahashi D; Isobe K; Inoue Y; Takeishi K; Takeda N; Sasaki S; Uchida S
    Hum Mol Genet; 2014 Oct; 23(19):5052-60. PubMed ID: 24821705
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of a novel KLHL3-interacting motif in the C-terminal region of WNK4.
    Wang L; Wu G; Peng JB
    Biochem Biophys Res Commun; 2023 Aug; 670():87-93. PubMed ID: 37285722
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Decrease of WNK4 ubiquitination by disease-causing mutations of KLHL3 through different molecular mechanisms.
    Mori Y; Wakabayashi M; Mori T; Araki Y; Sohara E; Rai T; Sasaki S; Uchida S
    Biochem Biophys Res Commun; 2013 Sep; 439(1):30-4. PubMed ID: 23962426
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice.
    Maeoka Y; Ferdaus MZ; Cornelius RJ; Sharma A; Su XT; Miller LN; Robertson JA; Gurley SB; Yang CL; Ellison DH; McCormick JA
    J Am Soc Nephrol; 2022 Mar; 33(3):584-600. PubMed ID: 35064051
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension.
    Wakabayashi M; Mori T; Isobe K; Sohara E; Susa K; Araki Y; Chiga M; Kikuchi E; Nomura N; Mori Y; Matsuo H; Murata T; Nomura S; Asano T; Kawaguchi H; Nonoyama S; Rai T; Sasaki S; Uchida S
    Cell Rep; 2013 Mar; 3(3):858-68. PubMed ID: 23453970
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Decreased KLHL3 expression is involved in the activation of WNK-OSR1/SPAK-NCC cascade in type 1 diabetic mice.
    Guo Q; Zhang Y; Jiang GR; Zhang C
    Pflugers Arch; 2021 Feb; 473(2):185-196. PubMed ID: 33432425
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of KLHL3 and dietary K
    Ostrosky-Frid M; Chávez-Canales M; Zhang J; Andrukhova O; Argaiz ER; Lerdo-de-Tejada F; Murillo-de-Ozores A; Sanchez-Navarro A; Rojas-Vega L; Bobadilla NA; Vazquez N; Castañeda-Bueno M; Alessi DR; Gamba G
    Am J Physiol Renal Physiol; 2021 May; 320(5):F734-F747. PubMed ID: 33682442
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kelch-like 3/Cullin 3 ubiquitin ligase complex and WNK signaling in salt-sensitive hypertension and electrolyte disorder.
    Sohara E; Uchida S
    Nephrol Dial Transplant; 2016 Sep; 31(9):1417-24. PubMed ID: 26152401
    [TBL] [Abstract][Full Text] [Related]  

  • 12. WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3.
    Susa K; Sohara E; Takahashi D; Okado T; Rai T; Uchida S
    Biochem Biophys Res Commun; 2017 Sep; 491(3):727-732. PubMed ID: 28743496
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Unveiling the Distinct Mechanisms by which Disease-Causing Mutations in the Kelch Domain of KLHL3 Disrupt the Interaction with the Acidic Motif of WNK4 through Molecular Dynamics Simulation.
    Wang L; Jiang C; Cai R; Chen XZ; Peng JB
    Biochemistry; 2019 Apr; 58(16):2105-2115. PubMed ID: 30931564
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Generation and analysis of a mouse model of pseudohypoaldosteronism type II caused by KLHL3 mutation in BTB domain.
    Lin CM; Cheng CJ; Yang SS; Tseng MH; Yen MT; Sung CC; Lin SH
    FASEB J; 2019 Jan; 33(1):1051-1061. PubMed ID: 30148674
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of blood pressure and renal electrolyte balance by Cullin-RING ligases.
    Uchida S
    Curr Opin Nephrol Hypertens; 2014 Sep; 23(5):487-93. PubMed ID: 24992566
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dysregulation of the WNK4-SPAK/OSR1 pathway has a minor effect on baseline NKCC2 phosphorylation.
    Maeoka Y; Nguyen LT; Sharma A; Cornelius RJ; Su XT; Gutierrez MR; Carbajal-Contreras H; Castañeda-Bueno M; Gamba G; McCormick JA
    Am J Physiol Renal Physiol; 2024 Jan; 326(1):F39-F56. PubMed ID: 37881876
    [TBL] [Abstract][Full Text] [Related]  

  • 17. WNK kinases regulate thiazide-sensitive Na-Cl cotransport.
    Yang CL; Angell J; Mitchell R; Ellison DH
    J Clin Invest; 2003 Apr; 111(7):1039-45. PubMed ID: 12671053
    [TBL] [Abstract][Full Text] [Related]  

  • 18.
    Sasaki E; Susa K; Mori T; Isobe K; Araki Y; Inoue Y; Yoshizaki Y; Ando F; Mori Y; Mandai S; Zeniya M; Takahashi D; Nomura N; Rai T; Uchida S; Sohara E
    Mol Cell Biol; 2017 Apr; 37(7):. PubMed ID: 28052936
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Angiotensin II signaling via protein kinase C phosphorylates Kelch-like 3, preventing WNK4 degradation.
    Shibata S; Arroyo JP; Castañeda-Bueno M; Puthumana J; Zhang J; Uchida S; Stone KL; Lam TT; Lifton RP
    Proc Natl Acad Sci U S A; 2014 Oct; 111(43):15556-61. PubMed ID: 25313067
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension.
    Cornelius RJ; Zhang C; Erspamer KJ; Agbor LN; Sigmund CD; Singer JD; Yang CL; Ellison DH
    Am J Physiol Renal Physiol; 2018 Oct; 315(4):F1006-F1018. PubMed ID: 29897280
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.