BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 23668926)

  • 21. Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.
    Kim SH; Kowalski ML; Carson RP; Bridges LR; Ess KC
    Dis Model Mech; 2013 Jul; 6(4):925-33. PubMed ID: 23580196
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy.
    Wander SA; Hennessy BT; Slingerland JM
    J Clin Invest; 2011 Apr; 121(4):1231-41. PubMed ID: 21490404
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Loss of p27 Associated with Risk for Endometrial Carcinoma Arising in the Setting of Obesity.
    McCampbell AS; Mittelstadt ML; Dere R; Kim S; Zhou L; Djordjevic B; Soliman PT; Zhang Q; Wei C; Hursting SD; Lu KH; Broaddus RR; Walker CL
    Curr Mol Med; 2016; 16(3):252-65. PubMed ID: 26917264
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The Effect of LKB1 Activity on the Sensitivity to PI3K/mTOR Inhibition in Non-Small Cell Lung Cancer.
    Shukuya T; Yamada T; Koenig MJ; Xu J; Okimoto T; Li F; Amann JM; Carbone DP
    J Thorac Oncol; 2019 Jun; 14(6):1061-1076. PubMed ID: 30825612
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Fetal brain mTOR signaling activation in tuberous sclerosis complex.
    Tsai V; Parker WE; Orlova KA; Baybis M; Chi AW; Berg BD; Birnbaum JF; Estevez J; Okochi K; Sarnat HB; Flores-Sarnat L; Aronica E; Crino PB
    Cereb Cortex; 2014 Feb; 24(2):315-27. PubMed ID: 23081885
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK.
    Avivar-Valderas A; Bobrovnikova-Marjon E; Alan Diehl J; Bardeesy N; Debnath J; Aguirre-Ghiso JA
    Oncogene; 2013 Oct; 32(41):4932-40. PubMed ID: 23160380
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response.
    Babcock JT; Nguyen HB; He Y; Hendricks JW; Wek RC; Quilliam LA
    J Biol Chem; 2013 May; 288(22):15687-98. PubMed ID: 23612979
    [TBL] [Abstract][Full Text] [Related]  

  • 28. United at last: the tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target of rapamycin (mTOR) signalling.
    Manning BD; Cantley LC
    Biochem Soc Trans; 2003 Jun; 31(Pt 3):573-8. PubMed ID: 12773158
    [TBL] [Abstract][Full Text] [Related]  

  • 29. TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1.
    Plescher M; Teleman AA; Demetriades C
    Sci Rep; 2015 Sep; 5():13828. PubMed ID: 26345496
    [TBL] [Abstract][Full Text] [Related]  

  • 30. ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling.
    Winter JN; Jefferson LS; Kimball SR
    Am J Physiol Cell Physiol; 2011 May; 300(5):C1172-80. PubMed ID: 21289294
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.
    Tripathi DN; Chowdhury R; Trudel LJ; Tee AR; Slack RS; Walker CL; Wogan GN
    Proc Natl Acad Sci U S A; 2013 Aug; 110(32):E2950-7. PubMed ID: 23878245
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes.
    Miyazaki M; McCarthy JJ; Esser KA
    FEBS J; 2010 May; 277(9):2180-91. PubMed ID: 20412061
    [TBL] [Abstract][Full Text] [Related]  

  • 33. mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome.
    Shackelford DB; Vasquez DS; Corbeil J; Wu S; Leblanc M; Wu CL; Vera DR; Shaw RJ
    Proc Natl Acad Sci U S A; 2009 Jul; 106(27):11137-42. PubMed ID: 19541609
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The long and winding road to rational treatment of cancer associated with LKB1/AMPK/TSC/mTORC1 signaling.
    van Veelen W; Korsse SE; van de Laar L; Peppelenbosch MP
    Oncogene; 2011 May; 30(20):2289-303. PubMed ID: 21258412
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation.
    Lai LP; Lilley BN; Sanes JR; McMahon AP
    Proc Natl Acad Sci U S A; 2013 Nov; 110(48):19450-5. PubMed ID: 24218567
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Endothelial Cell mTOR Complex-2 Regulates Sprouting Angiogenesis.
    Farhan MA; Carmine-Simmen K; Lewis JD; Moore RB; Murray AG
    PLoS One; 2015; 10(8):e0135245. PubMed ID: 26295809
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Targeting mTOR globally in cancer: thinking beyond rapamycin.
    Shor B; Gibbons JJ; Abraham RT; Yu K
    Cell Cycle; 2009 Dec; 8(23):3831-7. PubMed ID: 19901542
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling.
    Miyazaki M; McCarthy JJ; Fedele MJ; Esser KA
    J Physiol; 2011 Apr; 589(Pt 7):1831-46. PubMed ID: 21300751
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The TSC1-TSC2 complex is required for proper activation of mTOR complex 2.
    Huang J; Dibble CC; Matsuzaki M; Manning BD
    Mol Cell Biol; 2008 Jun; 28(12):4104-15. PubMed ID: 18411301
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mind the GAP: Wnt steps onto the mTORC1 train.
    Choo AY; Roux PP; Blenis J
    Cell; 2006 Sep; 126(5):834-6. PubMed ID: 16959561
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.