BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 23669381)

  • 1. Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses.
    Prichard MN; Williams JD; Komazin-Meredith G; Khan AR; Price NB; Jefferson GM; Harden EA; Hartline CB; Peet NP; Bowlin TL
    Antimicrob Agents Chemother; 2013 Aug; 57(8):3518-27. PubMed ID: 23669381
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro.
    Kushner NL; Williams SL; Hartline CB; Harden EA; Bidanset DJ; Chen X; Zemlicka J; Kern ER
    Nucleosides Nucleotides Nucleic Acids; 2003 Dec; 22(12):2105-19. PubMed ID: 14714760
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclopropavir inhibits the normal function of the human cytomegalovirus UL97 kinase.
    James SH; Hartline CB; Harden EA; Driebe EM; Schupp JM; Engelthaler DM; Keim PS; Bowlin TL; Kern ER; Prichard MN
    Antimicrob Agents Chemother; 2011 Oct; 55(10):4682-91. PubMed ID: 21788463
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.
    Zhou S; Kern ER; Gullen E; Cheng YC; Drach JC; Tamiya S; Mitsuya H; Zemlicka J
    J Med Chem; 2006 Oct; 49(20):6120-8. PubMed ID: 17004726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions.
    Komazin-Meredith G; Chou S; Prichard MN; Hartline CB; Cardinale SC; Comeau K; Williams JD; Khan AR; Peet NP; Bowlin TL
    Antimicrob Agents Chemother; 2014; 58(1):274-8. PubMed ID: 24145545
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.
    Prichard MN; Quenelle DC; Hartline CB; Harden EA; Jefferson G; Frederick SL; Daily SL; Whitley RJ; Tiwari KN; Maddry JA; Secrist JA; Kern ER
    Antimicrob Agents Chemother; 2009 Dec; 53(12):5251-8. PubMed ID: 19770274
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides.
    Zhou S; Breitenbach JM; Borysko KZ; Drach JC; Kern ER; Gullen E; Cheng YC; Zemlicka J
    J Med Chem; 2004 Jan; 47(3):566-75. PubMed ID: 14736238
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and enantioselectivity of the antiviral effects of (R,Z)-,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninate prodrugs: influence of heterocyclic base, type of virus and host cells.
    Qiu YL; Geiser F; Kira T; Gullen E; Cheng YC; Ptak RG; Breitenbach JM; Drach JC; Hartline CB; Kern ER; Zemlicka J
    Antivir Chem Chemother; 2000 May; 11(3):191-202. PubMed ID: 10901290
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro activity and mechanism of action of methylenecyclopropane analogs of nucleosides against herpesvirus replication.
    Kern ER; Kushner NL; Hartline CB; Williams-Aziz SL; Harden EA; Zhou S; Zemlicka J; Prichard MN
    Antimicrob Agents Chemother; 2005 Mar; 49(3):1039-45. PubMed ID: 15728900
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides.
    Williams JD; Khan AR; Harden EA; Hartline CB; Jefferson GM; Keith KA; Prichard MN; Zemlicka J; Peet NP; Bowlin TL
    Bioorg Med Chem; 2012 Jun; 20(12):3710-8. PubMed ID: 22607883
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir.
    Li C; Quenelle DC; Prichard MN; Drach JC; Zemlicka J
    Bioorg Med Chem; 2012 Apr; 20(8):2669-74. PubMed ID: 22417649
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TAOK3 phosphorylates the methylenecyclopropane nucleoside MBX 2168 to its monophosphate.
    Komazin-Meredith G; Cardinale SC; Comeau K; Magalhaes KJ; Hartline CB; Williams JD; Opperman TJ; Prichard MN; Bowlin TL
    Antiviral Res; 2015 Jul; 119():23-7. PubMed ID: 25857706
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytomegalovirus mutants resistant to ganciclovir and cidofovir differ in susceptibilities to synguanol and its 6-ether and 6-thioether derivatives.
    Chou S; Komazin-Meredith G; Williams JD; Bowlin TL
    Antimicrob Agents Chemother; 2014; 58(3):1809-12. PubMed ID: 24379208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro.
    Williams-Aziz SL; Hartline CB; Harden EA; Daily SL; Prichard MN; Kushner NL; Beadle JR; Wan WB; Hostetler KY; Kern ER
    Antimicrob Agents Chemother; 2005 Sep; 49(9):3724-33. PubMed ID: 16127046
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of 6-Alkoxy-Substituted Methylenecyclopropane Nucleoside Analogs Requires Enzymatic Modification by Adenosine Deaminase-Like Protein 1.
    Vollmer KJ; Burns AC; Sauer HE; Williams JD; Komazin-Meredith G; Cardinale S; Butler M; Aron Z; Hussein I; Busch MG; Bowlin TL; Gentry BG
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31332074
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The UL97 protein kinase of human cytomegalovirus and homologues in other herpesviruses: impact on virus and host.
    Michel D; Mertens T
    Biochim Biophys Acta; 2004 Mar; 1697(1-2):169-80. PubMed ID: 15023359
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphoralaninate pronucleotides of pyrimidine methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity.
    Ambrose A; Zemlicka J; Kern ER; Drach JC; Gullen E; Cheng YC
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(10-12):1763-74. PubMed ID: 16438046
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-activity relationships of (S,Z)-2-aminopurine methylenecyclopropane analogues of nucleosides. Variation of purine-6 substituents and activity against herpesviruses and hepatitis B virus.
    Chen X; Kern ER; Drach JC; Gullen E; Cheng YC; Zemlicka J
    J Med Chem; 2003 Apr; 46(8):1531-7. PubMed ID: 12672254
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of herpesvirus replication by hexadecyloxypropyl esters of purine- and pyrimidine-based phosphonomethoxyethyl nucleoside phosphonates.
    Prichard MN; Hartline CB; Harden EA; Daily SL; Beadle JR; Valiaeva N; Kern ER; Hostetler KY
    Antimicrob Agents Chemother; 2008 Dec; 52(12):4326-30. PubMed ID: 18852272
    [TBL] [Abstract][Full Text] [Related]  

  • 20. (Z)- and (E)-2-(hydroxymethylcyclopropylidene)-methylpurines and pyrimidines as antiviral agents.
    Qiu YL; Ptak RG; Breitenbach JM; Lin JS; Cheng YC; Kern ER; Drach JC; Zemlicka J
    Antivir Chem Chemother; 1998 Jul; 9(4):341-52. PubMed ID: 9875413
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.