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2. Pharmacologic inhibition of Jak2-Stat5 signaling By Jak2 inhibitor AZD1480 potently suppresses growth of both primary and castrate-resistant prostate cancer. Gu L; Liao Z; Hoang DT; Dagvadorj A; Gupta S; Blackmon S; Ellsworth E; Talati P; Leiby B; Zinda M; Lallas CD; Trabulsi EJ; McCue P; Gomella L; Huszar D; Nevalainen MT Clin Cancer Res; 2013 Oct; 19(20):5658-74. PubMed ID: 23942095 [TBL] [Abstract][Full Text] [Related]
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6. STAT5A/B Blockade Sensitizes Prostate Cancer to Radiation through Inhibition of RAD51 and DNA Repair. Maranto C; Udhane V; Hoang DT; Gu L; Alexeev V; Malas K; Cardenas K; Brody JR; Rodeck U; Bergom C; Iczkowski KA; Jacobsohn K; See W; Schmitt SM; Nevalainen MT Clin Cancer Res; 2018 Apr; 24(8):1917-1931. PubMed ID: 29483142 [No Abstract] [Full Text] [Related]
7. Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia. Liao Z; Gu L; Vergalli J; Mariani SA; De Dominici M; Lokareddy RK; Dagvadorj A; Purushottamachar P; McCue PA; Trabulsi E; Lallas CD; Gupta S; Ellsworth E; Blackmon S; Ertel A; Fortina P; Leiby B; Xia G; Rui H; Hoang DT; Gomella LG; Cingolani G; Njar V; Pattabiraman N; Calabretta B; Nevalainen MT Mol Cancer Ther; 2015 Aug; 14(8):1777-93. PubMed ID: 26026053 [TBL] [Abstract][Full Text] [Related]
8. Signal transducer and activator of transcription 5A/B in prostate and breast cancers. Tan SH; Nevalainen MT Endocr Relat Cancer; 2008 Jun; 15(2):367-90. PubMed ID: 18508994 [TBL] [Abstract][Full Text] [Related]
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11. Metastatic phenotype in CWR22 prostate cancer xenograft following castration. Seedhouse SJ; Affronti HC; Karasik E; Gillard BM; Azabdaftari G; Smiraglia DJ; Foster BA Prostate; 2016 Mar; 76(4):359-68. PubMed ID: 26642837 [TBL] [Abstract][Full Text] [Related]
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17. Obesity is associated with castration-resistant disease and metastasis in men treated with androgen deprivation therapy after radical prostatectomy: results from the SEARCH database. Keto CJ; Aronson WJ; Terris MK; Presti JC; Kane CJ; Amling CL; Freedland SJ BJU Int; 2012 Aug; 110(4):492-8. PubMed ID: 22094083 [TBL] [Abstract][Full Text] [Related]
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