BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 23677771)

  • 1. Clinical pharmacology of axitinib.
    Chen Y; Tortorici MA; Garrett M; Hee B; Klamerus KJ; Pithavala YK
    Clin Pharmacokinet; 2013 Sep; 52(9):713-25. PubMed ID: 23677771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Population pharmacokinetic analysis of axitinib in healthy volunteers.
    Garrett M; Poland B; Brennan M; Hee B; Pithavala YK; Amantea MA
    Br J Clin Pharmacol; 2014 Mar; 77(3):480-92. PubMed ID: 23834452
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteers.
    Pithavala YK; Tong W; Mount J; Rahavendran SV; Garrett M; Hee B; Selaru P; Sarapa N; Klamerus KJ
    Invest New Drugs; 2012 Feb; 30(1):273-81. PubMed ID: 20740300
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacokinetics, metabolism, and excretion of [14C]axitinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in humans.
    Smith BJ; Pithavala Y; Bu HZ; Kang P; Hee B; Deese AJ; Pool WF; Klamerus KJ; Wu EY; Dalvie DK
    Drug Metab Dispos; 2014 May; 42(5):918-31. PubMed ID: 24608633
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In Vitro Kinetic Characterization of Axitinib Metabolism.
    Zientek MA; Goosen TC; Tseng E; Lin J; Bauman JN; Walker GS; Kang P; Jiang Y; Freiwald S; Neul D; Smith BJ
    Drug Metab Dispos; 2016 Jan; 44(1):102-14. PubMed ID: 26512042
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacokinetics of single-agent axitinib across multiple solid tumor types.
    Tortorici MA; Cohen EE; Pithavala YK; Garrett M; Ruiz-Garcia A; Kim S; Fruehauf JP
    Cancer Chemother Pharmacol; 2014 Dec; 74(6):1279-89. PubMed ID: 25336084
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Meta-analysis of contribution of genetic polymorphisms in drug-metabolizing enzymes or transporters to axitinib pharmacokinetics.
    Brennan M; Williams JA; Chen Y; Tortorici M; Pithavala Y; Liu YC
    Eur J Clin Pharmacol; 2012 May; 68(5):645-55. PubMed ID: 22170007
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Axitinib plasma pharmacokinetics and ethnic differences.
    Chen Y; Suzuki A; Tortorici MA; Garrett M; LaBadie RR; Umeyama Y; Pithavala YK
    Invest New Drugs; 2015 Apr; 33(2):521-32. PubMed ID: 25663295
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lack of effect of smoking status on axitinib pharmacokinetics in patients with non-small-cell lung cancer.
    Garrett M; Taylor T; Mould DR; Amantea MA; Chen Y; Ingrosso A; Pithavala YK
    Cancer Chemother Pharmacol; 2016 Dec; 78(6):1131-1141. PubMed ID: 27783139
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of Renal Impairment on the Pharmacokinetics and Safety of Axitinib.
    Chen Y; Rini BI; Motzer RJ; Dutcher JP; Rixe O; Wilding G; Stadler WM; Tarazi J; Garrett M; Pithavala YK
    Target Oncol; 2016 Apr; 11(2):229-34. PubMed ID: 26400730
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Clinical Pharmacology of Brigatinib: A Next-Generation Anaplastic Lymphoma Kinase Inhibitor.
    Gupta N; Hanley MJ; Griffin RJ; Zhang P; Venkatakrishnan K; Sinha V
    Clin Pharmacokinet; 2023 Aug; 62(8):1063-1079. PubMed ID: 37493887
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Axitinib in metastatic renal cell carcinoma: results of a pharmacokinetic and pharmacodynamic analysis.
    Rini BI; Garrett M; Poland B; Dutcher JP; Rixe O; Wilding G; Stadler WM; Pithavala YK; Kim S; Tarazi J; Motzer RJ
    J Clin Pharmacol; 2013 May; 53(5):491-504. PubMed ID: 23553560
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clinical pharmacokinetics and pharmacodynamics of linagliptin.
    Graefe-Mody U; Retlich S; Friedrich C
    Clin Pharmacokinet; 2012 Jul; 51(7):411-27. PubMed ID: 22568694
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of axitinib on the QT interval in healthy volunteers.
    Ruiz-Garcia A; Houk BE; Pithavala YK; Toh M; Sarapa N; Tortorici MA
    Cancer Chemother Pharmacol; 2015 Mar; 75(3):619-28. PubMed ID: 25589220
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on axitinib brain accumulation and oral plasma pharmacokinetics.
    Poller B; Iusuf D; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
    Drug Metab Dispos; 2011 May; 39(5):729-35. PubMed ID: 21282407
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Contribution of UGT1A1 genetic polymorphisms related to axitinib pharmacokinetics to safety and efficacy in patients with renal cell carcinoma.
    Igarashi R; Inoue T; Fujiyama N; Tsuchiya N; Numakura K; Kagaya H; Saito M; Narita S; Satoh S; Niioka T; Miura M; Habuchi T
    Med Oncol; 2018 Mar; 35(4):51. PubMed ID: 29524031
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of rifampin on the pharmacokinetics of Axitinib (AG-013736) in Japanese and Caucasian healthy volunteers.
    Pithavala YK; Tortorici M; Toh M; Garrett M; Hee B; Kuruganti U; Ni G; Klamerus KJ
    Cancer Chemother Pharmacol; 2010 Feb; 65(3):563-70. PubMed ID: 19603168
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacokinetic drug interactions between clobazam and drugs metabolized by cytochrome P450 isoenzymes.
    Walzer M; Bekersky I; Blum RA; Tolbert D
    Pharmacotherapy; 2012 Apr; 32(4):340-53. PubMed ID: 22422635
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Axitinib for the management of metastatic renal cell carcinoma.
    Escudier B; Gore M
    Drugs R D; 2011; 11(2):113-26. PubMed ID: 21679004
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Population pharmacokinetic-pharmacodynamic modelling of 24-h diastolic ambulatory blood pressure changes mediated by axitinib in patients with metastatic renal cell carcinoma.
    Chen Y; Rini BI; Bair AH; Mugundu GM; Pithavala YK
    Clin Pharmacokinet; 2015 Apr; 54(4):397-407. PubMed ID: 25343945
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.