BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

337 related articles for article (PubMed ID: 23679895)

  • 1. Convergent evolution of chromatin modification by structurally distinct enzymes: comparative enzymology of histone H3 Lys²⁷ methylation by human polycomb repressive complex 2 and vSET.
    Swalm BM; Hallenbeck KK; Majer CR; Jin L; Scott MP; Moyer MP; Copeland RA; Wigle TJ
    Biochem J; 2013 Jul; 453(2):241-7. PubMed ID: 23679895
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enzyme-dependent lysine deprotonation in EZH2 catalysis.
    Kipp DR; Quinn CM; Fortin PD
    Biochemistry; 2013 Oct; 52(39):6866-78. PubMed ID: 24000826
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).
    McCabe MT; Graves AP; Ganji G; Diaz E; Halsey WS; Jiang Y; Smitheman KN; Ott HM; Pappalardi MB; Allen KE; Chen SB; Della Pietra A; Dul E; Hughes AM; Gilbert SA; Thrall SH; Tummino PJ; Kruger RG; Brandt M; Schwartz B; Creasy CL
    Proc Natl Acad Sci U S A; 2012 Feb; 109(8):2989-94. PubMed ID: 22323599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation.
    Ott HM; Graves AP; Pappalardi MB; Huddleston M; Halsey WS; Hughes AM; Groy A; Dul E; Jiang Y; Bai Y; Annan R; Verma SK; Knight SD; Kruger RG; Dhanak D; Schwartz B; Tummino PJ; Creasy CL; McCabe MT
    Mol Cancer Ther; 2014 Dec; 13(12):3062-73. PubMed ID: 25253781
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dimerization of a viral SET protein endows its function.
    Wei H; Zhou MM
    Proc Natl Acad Sci U S A; 2010 Oct; 107(43):18433-8. PubMed ID: 20937900
    [TBL] [Abstract][Full Text] [Related]  

  • 6. EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation.
    Mu W; Starmer J; Yee D; Magnuson T
    Epigenetics Chromatin; 2018 Dec; 11(1):71. PubMed ID: 30522506
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2.
    Lee CH; Holder M; Grau D; Saldaña-Meyer R; Yu JR; Ganai RA; Zhang J; Wang M; LeRoy G; Dobenecker MW; Reinberg D; Armache KJ
    Mol Cell; 2018 May; 70(3):435-448.e5. PubMed ID: 29681498
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation.
    Caretti G; Di Padova M; Micales B; Lyons GE; Sartorelli V
    Genes Dev; 2004 Nov; 18(21):2627-38. PubMed ID: 15520282
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of Retinal Development via the Epigenetic Modification of Histone H3.
    Watanabe S; Murakami A
    Adv Exp Med Biol; 2016; 854():635-41. PubMed ID: 26427469
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of histone methylation by automethylation of PRC2.
    Wang X; Long Y; Paucek RD; Gooding AR; Lee T; Burdorf RM; Cech TR
    Genes Dev; 2019 Oct; 33(19-20):1416-1427. PubMed ID: 31488576
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma.
    Natsume A; Ito M; Katsushima K; Ohka F; Hatanaka A; Shinjo K; Sato S; Takahashi S; Ishikawa Y; Takeuchi I; Shimogawa H; Uesugi M; Okano H; Kim SU; Wakabayashi T; Issa JP; Sekido Y; Kondo Y
    Cancer Res; 2013 Jul; 73(14):4559-70. PubMed ID: 23720055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Global histone H3 lysine 27 triple methylation levels are reduced in vessels with advanced atherosclerotic plaques.
    Wierda RJ; Rietveld IM; van Eggermond MC; Belien JA; van Zwet EW; Lindeman JH; van den Elsen PJ
    Life Sci; 2015 May; 129():3-9. PubMed ID: 25445221
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase.
    Jackson JP; Lindroth AM; Cao X; Jacobsen SE
    Nature; 2002 Apr; 416(6880):556-60. PubMed ID: 11898023
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3.
    Manzur KL; Farooq A; Zeng L; Plotnikova O; Koch AW; Sachchidanand ; Zhou MM
    Nat Struct Biol; 2003 Mar; 10(3):187-96. PubMed ID: 12567185
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation.
    Laugesen A; Højfeldt JW; Helin K
    Mol Cell; 2019 Apr; 74(1):8-18. PubMed ID: 30951652
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation.
    Yuan W; Wu T; Fu H; Dai C; Wu H; Liu N; Li X; Xu M; Zhang Z; Niu T; Han Z; Chai J; Zhou XJ; Gao S; Zhu B
    Science; 2012 Aug; 337(6097):971-5. PubMed ID: 22923582
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.
    Kogure M; Takawa M; Saloura V; Sone K; Piao L; Ueda K; Ibrahim R; Tsunoda T; Sugiyama M; Atomi Y; Nakamura Y; Hamamoto R
    Neoplasia; 2013 Nov; 15(11):1251-61. PubMed ID: 24339737
    [TBL] [Abstract][Full Text] [Related]  

  • 18. EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.
    Shen X; Liu Y; Hsu YJ; Fujiwara Y; Kim J; Mao X; Yuan GC; Orkin SH
    Mol Cell; 2008 Nov; 32(4):491-502. PubMed ID: 19026780
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histone methylation by PRC2 is inhibited by active chromatin marks.
    Schmitges FW; Prusty AB; Faty M; Stützer A; Lingaraju GM; Aiwazian J; Sack R; Hess D; Li L; Zhou S; Bunker RD; Wirth U; Bouwmeester T; Bauer A; Ly-Hartig N; Zhao K; Chan H; Gu J; Gut H; Fischle W; Müller J; Thomä NH
    Mol Cell; 2011 May; 42(3):330-41. PubMed ID: 21549310
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencing.
    Mozzetta C; Pontis J; Fritsch L; Robin P; Portoso M; Proux C; Margueron R; Ait-Si-Ali S
    Mol Cell; 2014 Jan; 53(2):277-89. PubMed ID: 24389103
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.