BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

282 related articles for article (PubMed ID: 23685997)

  • 1. Immunohistochemical and molecular pathology of ocular uveal melanocytoma: evidence for somatic GNAQ mutations.
    Mudhar HS; Doherty R; Salawu A; Sisley K; Rennie IG
    Br J Ophthalmol; 2013 Jul; 97(7):924-8. PubMed ID: 23685997
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Iris and Ciliary Body Melanocytomas Are Defined by Solitary GNAQ Mutation Without Additional Oncogenic Alterations.
    Solomon DA; Ramani B; Eiger-Moscovich M; Milman T; Uludag G; Crawford JB; Phan I; Char DH; Shields CL; Eagle RC; Bastian BC; Bloomer MM; Pekmezci M
    Ophthalmology; 2022 Dec; 129(12):1429-1439. PubMed ID: 35835335
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.
    Ominato J; Fukuchi T; Sato A; Yamaguchi N; Kobayashi K; Cho H; Oyama T; Ajioka Y
    Appl Immunohistochem Mol Morphol; 2018 Oct; 26(9):658-663. PubMed ID: 28248732
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lack of oncogenic GNAQ mutations in melanocytic lesions of the conjunctiva as compared to uveal melanoma.
    Dratviman-Storobinsky O; Cohen Y; Frenkel S; Pe'er J; Goldenberg-Cohen N
    Invest Ophthalmol Vis Sci; 2010 Dec; 51(12):6180-2. PubMed ID: 20631239
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese.
    Xu X; Wei WB; Li B; Gao F; Zhang Z; Jonas JB
    PLoS One; 2014; 9(10):e109699. PubMed ID: 25280020
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prognostic impact of chromosomal aberrations and GNAQ, GNA11 and BAP1 mutations in uveal melanoma.
    Staby KM; Gravdal K; Mørk SJ; Heegaard S; Vintermyr OK; Krohn J
    Acta Ophthalmol; 2018 Feb; 96(1):31-38. PubMed ID: 28444874
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutations in GNA11 in uveal melanoma.
    Van Raamsdonk CD; Griewank KG; Crosby MB; Garrido MC; Vemula S; Wiesner T; Obenauf AC; Wackernagel W; Green G; Bouvier N; Sozen MM; Baimukanova G; Roy R; Heguy A; Dolgalev I; Khanin R; Busam K; Speicher MR; O'Brien J; Bastian BC
    N Engl J Med; 2010 Dec; 363(23):2191-9. PubMed ID: 21083380
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.
    Schneider B; Riedel K; Zhivov A; Huehns M; Zettl H; Guthoff RF; Jünemann A; Erbersdobler A; Zimpfer A
    Pathol Oncol Res; 2019 Oct; 25(4):1319-1325. PubMed ID: 29209985
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of unique MEK-dependent genes in GNAQ mutant uveal melanoma involved in cell growth, tumor cell invasion, and MEK resistance.
    Ambrosini G; Pratilas CA; Qin LX; Tadi M; Surriga O; Carvajal RD; Schwartz GK
    Clin Cancer Res; 2012 Jul; 18(13):3552-61. PubMed ID: 22550165
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic and clinico-pathologic analysis of metastatic uveal melanoma.
    Griewank KG; van de Nes J; Schilling B; Moll I; Sucker A; Kakavand H; Haydu LE; Asher M; Zimmer L; Hillen U; Thompson JF; Scolyer RA; Schadendorf D; Murali R
    Mod Pathol; 2014 Feb; 27(2):175-83. PubMed ID: 23887304
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SOX10 Expression as Well as BRAF and GNAQ/11 Mutations Distinguish Pigmented Ciliary Epithelium Neoplasms From Uveal Melanomas.
    Mori T; Sukeda A; Sekine S; Shibata S; Ryo E; Okano H; Suzuki S; Hiraoka N
    Invest Ophthalmol Vis Sci; 2017 Oct; 58(12):5445-5451. PubMed ID: 29059311
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner.
    Khalili JS; Yu X; Wang J; Hayes BC; Davies MA; Lizee G; Esmaeli B; Woodman SE
    Clin Cancer Res; 2012 Aug; 18(16):4345-55. PubMed ID: 22733540
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein kinase C inhibitor AEB071 targets ocular melanoma harboring GNAQ mutations via effects on the PKC/Erk1/2 and PKC/NF-κB pathways.
    Wu X; Li J; Zhu M; Fletcher JA; Hodi FS
    Mol Cancer Ther; 2012 Sep; 11(9):1905-14. PubMed ID: 22653968
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutations in g protein encoding genes and chromosomal alterations in primary leptomeningeal melanocytic neoplasms.
    Küsters-Vandevelde HV; van Engen-van Grunsven IA; Coupland SE; Lake SL; Rijntjes J; Pfundt R; Küsters B; Wesseling P; Blokx WA; Groenen PJ
    Pathol Oncol Res; 2015 Apr; 21(2):439-47. PubMed ID: 25315378
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of mutant GNAQ signaling in uveal melanoma induces AMPK-dependent autophagic cell death.
    Ambrosini G; Musi E; Ho AL; de Stanchina E; Schwartz GK
    Mol Cancer Ther; 2013 May; 12(5):768-76. PubMed ID: 23443802
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activating mutations of the GNAQ gene: a frequent event in primary melanocytic neoplasms of the central nervous system.
    Küsters-Vandevelde HV; Klaasen A; Küsters B; Groenen PJ; van Engen-van Grunsven IA; van Dijk MR; Reifenberger G; Wesseling P; Blokx WA
    Acta Neuropathol; 2010 Mar; 119(3):317-23. PubMed ID: 19936769
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Digital PCR validates 8q dosage as prognostic tool in uveal melanoma.
    Versluis M; de Lange MJ; van Pelt SI; Ruivenkamp CA; Kroes WG; Cao J; Jager MJ; Luyten GP; van der Velden PA
    PLoS One; 2015; 10(3):e0116371. PubMed ID: 25764247
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanoma.
    Wu X; Zhu M; Fletcher JA; Giobbie-Hurder A; Hodi FS
    PLoS One; 2012; 7(1):e29622. PubMed ID: 22253748
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Uveal Melanoma:
    Psinakis F; Katseli A; Koutsandrea C; Frangia K; Florentin L; Apostolopoulou D; Dimakopoulou K; Papakonstantinou D; Georgopoulou E; Brouzas D
    Anticancer Res; 2017 Oct; 37(10):5719-5726. PubMed ID: 28982892
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutation frequencies of GNAQ, GNA11, BAP1, SF3B1, EIF1AX and TERT in uveal melanoma: detection of an activating mutation in the TERT gene promoter in a single case of uveal melanoma.
    Dono M; Angelini G; Cecconi M; Amaro A; Esposito AI; Mirisola V; Maric I; Lanza F; Nasciuti F; Viaggi S; Gualco M; Bandelloni R; Truini M; Coviello DA; Zupo S; Mosci C; Pfeffer U
    Br J Cancer; 2014 Feb; 110(4):1058-65. PubMed ID: 24423917
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.