These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Iris and Ciliary Body Melanocytomas Are Defined by Solitary GNAQ Mutation Without Additional Oncogenic Alterations. Solomon DA; Ramani B; Eiger-Moscovich M; Milman T; Uludag G; Crawford JB; Phan I; Char DH; Shields CL; Eagle RC; Bastian BC; Bloomer MM; Pekmezci M Ophthalmology; 2022 Dec; 129(12):1429-1439. PubMed ID: 35835335 [TBL] [Abstract][Full Text] [Related]
3. The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan. Ominato J; Fukuchi T; Sato A; Yamaguchi N; Kobayashi K; Cho H; Oyama T; Ajioka Y Appl Immunohistochem Mol Morphol; 2018 Oct; 26(9):658-663. PubMed ID: 28248732 [TBL] [Abstract][Full Text] [Related]
4. Lack of oncogenic GNAQ mutations in melanocytic lesions of the conjunctiva as compared to uveal melanoma. Dratviman-Storobinsky O; Cohen Y; Frenkel S; Pe'er J; Goldenberg-Cohen N Invest Ophthalmol Vis Sci; 2010 Dec; 51(12):6180-2. PubMed ID: 20631239 [TBL] [Abstract][Full Text] [Related]
5. Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese. Xu X; Wei WB; Li B; Gao F; Zhang Z; Jonas JB PLoS One; 2014; 9(10):e109699. PubMed ID: 25280020 [TBL] [Abstract][Full Text] [Related]
6. Prognostic impact of chromosomal aberrations and GNAQ, GNA11 and BAP1 mutations in uveal melanoma. Staby KM; Gravdal K; Mørk SJ; Heegaard S; Vintermyr OK; Krohn J Acta Ophthalmol; 2018 Feb; 96(1):31-38. PubMed ID: 28444874 [TBL] [Abstract][Full Text] [Related]
7. Mutations in GNA11 in uveal melanoma. Van Raamsdonk CD; Griewank KG; Crosby MB; Garrido MC; Vemula S; Wiesner T; Obenauf AC; Wackernagel W; Green G; Bouvier N; Sozen MM; Baimukanova G; Roy R; Heguy A; Dolgalev I; Khanin R; Busam K; Speicher MR; O'Brien J; Bastian BC N Engl J Med; 2010 Dec; 363(23):2191-9. PubMed ID: 21083380 [TBL] [Abstract][Full Text] [Related]
8. Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas. Schneider B; Riedel K; Zhivov A; Huehns M; Zettl H; Guthoff RF; Jünemann A; Erbersdobler A; Zimpfer A Pathol Oncol Res; 2019 Oct; 25(4):1319-1325. PubMed ID: 29209985 [TBL] [Abstract][Full Text] [Related]
9. Identification of unique MEK-dependent genes in GNAQ mutant uveal melanoma involved in cell growth, tumor cell invasion, and MEK resistance. Ambrosini G; Pratilas CA; Qin LX; Tadi M; Surriga O; Carvajal RD; Schwartz GK Clin Cancer Res; 2012 Jul; 18(13):3552-61. PubMed ID: 22550165 [TBL] [Abstract][Full Text] [Related]
10. Genetic and clinico-pathologic analysis of metastatic uveal melanoma. Griewank KG; van de Nes J; Schilling B; Moll I; Sucker A; Kakavand H; Haydu LE; Asher M; Zimmer L; Hillen U; Thompson JF; Scolyer RA; Schadendorf D; Murali R Mod Pathol; 2014 Feb; 27(2):175-83. PubMed ID: 23887304 [TBL] [Abstract][Full Text] [Related]
11. SOX10 Expression as Well as BRAF and GNAQ/11 Mutations Distinguish Pigmented Ciliary Epithelium Neoplasms From Uveal Melanomas. Mori T; Sukeda A; Sekine S; Shibata S; Ryo E; Okano H; Suzuki S; Hiraoka N Invest Ophthalmol Vis Sci; 2017 Oct; 58(12):5445-5451. PubMed ID: 29059311 [TBL] [Abstract][Full Text] [Related]
12. Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner. Khalili JS; Yu X; Wang J; Hayes BC; Davies MA; Lizee G; Esmaeli B; Woodman SE Clin Cancer Res; 2012 Aug; 18(16):4345-55. PubMed ID: 22733540 [TBL] [Abstract][Full Text] [Related]
13. Protein kinase C inhibitor AEB071 targets ocular melanoma harboring GNAQ mutations via effects on the PKC/Erk1/2 and PKC/NF-κB pathways. Wu X; Li J; Zhu M; Fletcher JA; Hodi FS Mol Cancer Ther; 2012 Sep; 11(9):1905-14. PubMed ID: 22653968 [TBL] [Abstract][Full Text] [Related]
14. Mutations in g protein encoding genes and chromosomal alterations in primary leptomeningeal melanocytic neoplasms. Küsters-Vandevelde HV; van Engen-van Grunsven IA; Coupland SE; Lake SL; Rijntjes J; Pfundt R; Küsters B; Wesseling P; Blokx WA; Groenen PJ Pathol Oncol Res; 2015 Apr; 21(2):439-47. PubMed ID: 25315378 [TBL] [Abstract][Full Text] [Related]
15. Inhibition of mutant GNAQ signaling in uveal melanoma induces AMPK-dependent autophagic cell death. Ambrosini G; Musi E; Ho AL; de Stanchina E; Schwartz GK Mol Cancer Ther; 2013 May; 12(5):768-76. PubMed ID: 23443802 [TBL] [Abstract][Full Text] [Related]
16. Activating mutations of the GNAQ gene: a frequent event in primary melanocytic neoplasms of the central nervous system. Küsters-Vandevelde HV; Klaasen A; Küsters B; Groenen PJ; van Engen-van Grunsven IA; van Dijk MR; Reifenberger G; Wesseling P; Blokx WA Acta Neuropathol; 2010 Mar; 119(3):317-23. PubMed ID: 19936769 [TBL] [Abstract][Full Text] [Related]
17. Digital PCR validates 8q dosage as prognostic tool in uveal melanoma. Versluis M; de Lange MJ; van Pelt SI; Ruivenkamp CA; Kroes WG; Cao J; Jager MJ; Luyten GP; van der Velden PA PLoS One; 2015; 10(3):e0116371. PubMed ID: 25764247 [TBL] [Abstract][Full Text] [Related]
18. The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanoma. Wu X; Zhu M; Fletcher JA; Giobbie-Hurder A; Hodi FS PLoS One; 2012; 7(1):e29622. PubMed ID: 22253748 [TBL] [Abstract][Full Text] [Related]
20. Mutation frequencies of GNAQ, GNA11, BAP1, SF3B1, EIF1AX and TERT in uveal melanoma: detection of an activating mutation in the TERT gene promoter in a single case of uveal melanoma. Dono M; Angelini G; Cecconi M; Amaro A; Esposito AI; Mirisola V; Maric I; Lanza F; Nasciuti F; Viaggi S; Gualco M; Bandelloni R; Truini M; Coviello DA; Zupo S; Mosci C; Pfeffer U Br J Cancer; 2014 Feb; 110(4):1058-65. PubMed ID: 24423917 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]