These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. Vigueira PA; McCommis KS; Hodges WT; Schweitzer GG; Cole SL; Oonthonpan L; Taylor EB; McDonald WG; Kletzien RF; Colca JR; Finck BN Exp Physiol; 2017 Aug; 102(8):985-999. PubMed ID: 28597936 [TBL] [Abstract][Full Text] [Related]
3. Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Divakaruni AS; Wiley SE; Rogers GW; Andreyev AY; Petrosyan S; Loviscach M; Wall EA; Yadava N; Heuck AP; Ferrick DA; Henry RR; McDonald WG; Colca JR; Simon MI; Ciaraldi TP; Murphy AN Proc Natl Acad Sci U S A; 2013 Apr; 110(14):5422-7. PubMed ID: 23513224 [TBL] [Abstract][Full Text] [Related]
4. Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid. Chen Y; McCommis KS; Ferguson D; Hall AM; Harris CA; Finck BN Endocrinology; 2018 Feb; 159(2):609-621. PubMed ID: 29126303 [TBL] [Abstract][Full Text] [Related]
5. A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. Bricker DK; Taylor EB; Schell JC; Orsak T; Boutron A; Chen YC; Cox JE; Cardon CM; Van Vranken JG; Dephoure N; Redin C; Boudina S; Gygi SP; Brivet M; Thummel CS; Rutter J Science; 2012 Jul; 337(6090):96-100. PubMed ID: 22628558 [TBL] [Abstract][Full Text] [Related]
6. Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretion. Patterson JN; Cousteils K; Lou JW; Manning Fox JE; MacDonald PE; Joseph JW J Biol Chem; 2014 May; 289(19):13335-46. PubMed ID: 24675076 [TBL] [Abstract][Full Text] [Related]
7. The TZD insulin sensitizer clue provides a new route into diabetes drug discovery. Colca JR Expert Opin Drug Discov; 2015 Dec; 10(12):1259-70. PubMed ID: 26479699 [TBL] [Abstract][Full Text] [Related]
9. MPC1-like Is a Placental Mammal-specific Mitochondrial Pyruvate Carrier Subunit Expressed in Postmeiotic Male Germ Cells. Vanderperre B; Cermakova K; Escoffier J; Kaba M; Bender T; Nef S; Martinou JC J Biol Chem; 2016 Aug; 291(32):16448-61. PubMed ID: 27317664 [TBL] [Abstract][Full Text] [Related]
10. Analysis of Mitochondrial Proteins in the Surviving Myocardium after Ischemia Identifies Mitochondrial Pyruvate Carrier Expression as Possible Mediator of Tissue Viability. Fernández-Caggiano M; Prysyazhna O; Barallobre-Barreiro J; CalviñoSantos R; Aldama López G; Generosa Crespo-Leiro M; Eaton P; Doménech N Mol Cell Proteomics; 2016 Jan; 15(1):246-55. PubMed ID: 26582072 [TBL] [Abstract][Full Text] [Related]
11. Structural Insights into the Human Mitochondrial Pyruvate Carrier Complexes. Xu L; Phelix CF; Chen LY J Chem Inf Model; 2021 Nov; 61(11):5614-5625. PubMed ID: 34664967 [TBL] [Abstract][Full Text] [Related]
12. Pioglitazone inhibits mitochondrial pyruvate metabolism and glucose production in hepatocytes. Shannon CE; Daniele G; Galindo C; Abdul-Ghani MA; DeFronzo RA; Norton L FEBS J; 2017 Feb; 284(3):451-465. PubMed ID: 27987376 [TBL] [Abstract][Full Text] [Related]
13. Increased adipose expression of the uncoupling protein-3 gene by thiazolidinediones in Wistar fatty rats and in cultured adipocytes. Matsuda J; Hosoda K; Itoh H; Son C; Doi K; Hanaoka I; Inoue G; Nishimura H; Yoshimasa Y; Yamori Y; Odaka H; Nakao K Diabetes; 1998 Nov; 47(11):1809-14. PubMed ID: 9792555 [TBL] [Abstract][Full Text] [Related]
14. Mitochondrial pyruvate carrier: a potential target for diabetic nephropathy. Zhu H; Wan H; Wu L; Li Q; Liu S; Duan S; Huang Z; Zhang C; Zhang B; Xing C; Yuan Y BMC Nephrol; 2020 Jul; 21(1):274. PubMed ID: 32664896 [TBL] [Abstract][Full Text] [Related]
15. 5-Benzylidene, 5-benzyl, and 3-benzylthiazolidine-2,4-diones as potential inhibitors of the mitochondrial pyruvate carrier: Effects on mitochondrial functions and survival in Drosophila melanogaster. Touaibia M; St-Coeur PD; Duff P; Faye DC; Pichaud N Eur J Pharmacol; 2021 Dec; 913():174627. PubMed ID: 34774497 [TBL] [Abstract][Full Text] [Related]
16. Novel thiazolidinedione analog reduces a negative impact on bone and mesenchymal stem cell properties in obese mice compared to classical thiazolidinediones. Benova A; Ferencakova M; Bardova K; Funda J; Prochazka J; Spoutil F; Cajka T; Dzubanova M; Balcaen T; Kerckhofs G; Willekens W; van Lenthe GH; Alquicer G; Pecinova A; Mracek T; Horakova O; Rossmeisl M; Kopecky J; Tencerova M Mol Metab; 2022 Nov; 65():101598. PubMed ID: 36103974 [TBL] [Abstract][Full Text] [Related]
17. Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis. McCommis KS; Hodges WT; Brunt EM; Nalbantoglu I; McDonald WG; Holley C; Fujiwara H; Schaffer JE; Colca JR; Finck BN Hepatology; 2017 May; 65(5):1543-1556. PubMed ID: 28027586 [TBL] [Abstract][Full Text] [Related]
18. Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1. Li A; Liu Q; Li Q; Liu B; Yang Y; Zhang N EBioMedicine; 2018 Aug; 34():243-255. PubMed ID: 30093307 [TBL] [Abstract][Full Text] [Related]
19. Role of skeletal muscle in thiazolidinedione insulin sensitizer (PPARgamma agonist) action. Zierath JR; Ryder JW; Doebber T; Woods J; Wu M; Ventre J; Li Z; McCrary C; Berger J; Zhang B; Moller DE Endocrinology; 1998 Dec; 139(12):5034-41. PubMed ID: 9832442 [TBL] [Abstract][Full Text] [Related]
20. Screening for new inhibitors of the human Mitochondrial Pyruvate Carrier and their effects on hepatic glucose production and diabetes. Herzig S; Li L; Jiménez-Sánchez C; Martinou JC; Maechler P Biochim Biophys Acta Gen Subj; 2023 Dec; 1867(12):130492. PubMed ID: 37871770 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]