BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

381 related articles for article (PubMed ID: 23692380)

  • 1. Preclinical potency and safety studies of an AAV2-mediated gene therapy vector for the treatment of MERTK associated retinitis pigmentosa.
    Conlon TJ; Deng WT; Erger K; Cossette T; Pang JJ; Ryals R; Clément N; Cleaver B; McDoom I; Boye SE; Peden MC; Sherwood MB; Abernathy CR; Alkuraya FS; Boye SL; Hauswirth WW
    Hum Gene Ther Clin Dev; 2013 Mar; 24(1):23-8. PubMed ID: 23692380
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Treatment of retinitis pigmentosa due to MERTK mutations by ocular subretinal injection of adeno-associated virus gene vector: results of a phase I trial.
    Ghazi NG; Abboud EB; Nowilaty SR; Alkuraya H; Alhommadi A; Cai H; Hou R; Deng WT; Boye SL; Almaghamsi A; Al Saikhan F; Al-Dhibi H; Birch D; Chung C; Colak D; LaVail MM; Vollrath D; Erger K; Wang W; Conlon T; Zhang K; Hauswirth W; Alkuraya FS
    Hum Genet; 2016 Mar; 135(3):327-43. PubMed ID: 26825853
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gene Therapy for MERTK-Associated Retinal Degenerations.
    LaVail MM; Yasumura D; Matthes MT; Yang H; Hauswirth WW; Deng WT; Vollrath D
    Adv Exp Med Biol; 2016; 854():487-93. PubMed ID: 26427450
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AAV-Mediated gene transfer slows photoreceptor loss in the RCS rat model of retinitis pigmentosa.
    Smith AJ; Schlichtenbrede FC; Tschernutter M; Bainbridge JW; Thrasher AJ; Ali RR
    Mol Ther; 2003 Aug; 8(2):188-95. PubMed ID: 12907141
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy.
    Tschernutter M; Schlichtenbrede FC; Howe S; Balaggan KS; Munro PM; Bainbridge JW; Thrasher AJ; Smith AJ; Ali RR
    Gene Ther; 2005 Apr; 12(8):694-701. PubMed ID: 15660111
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tyrosine-mutant AAV8 delivery of human MERTK provides long-term retinal preservation in RCS rats.
    Deng WT; Dinculescu A; Li Q; Boye SL; Li J; Gorbatyuk MS; Pang J; Chiodo VA; Matthes MT; Yasumura D; Liu L; Alkuraya FS; Zhang K; Vollrath D; LaVail MM; Hauswirth WW
    Invest Ophthalmol Vis Sci; 2012 Apr; 53(4):1895-904. PubMed ID: 22408006
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency.
    Lew DS; Mazzoni F; Finnemann SC
    Front Immunol; 2020; 11():1463. PubMed ID: 32765507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk.
    Vollrath D; Feng W; Duncan JL; Yasumura D; D'Cruz PM; Chappelow A; Matthes MT; Kay MA; LaVail MM
    Proc Natl Acad Sci U S A; 2001 Oct; 98(22):12584-9. PubMed ID: 11592982
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dose Range Finding Studies with Two
    Song C; Dufour VL; Cideciyan AV; Ye GJ; Swider M; Newmark JA; Timmers AM; Robinson PM; Knop DR; Chulay JD; Jacobson SG; Aguirre GD; Beltran WA; Shearman MS
    Hum Gene Ther; 2020 Jul; 31(13-14):743-755. PubMed ID: 32414297
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prospects for gene therapy.
    Ali RR
    Novartis Found Symp; 2004; 255():165-72; discussion 173-8. PubMed ID: 14750603
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MERTK interactions with SH2-domain proteins in the retinal pigment epithelium.
    Shelby SJ; Colwill K; Dhe-Paganon S; Pawson T; Thompson DA
    PLoS One; 2013; 8(2):e53964. PubMed ID: 23390493
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR Mutations.
    Beltran WA; Cideciyan AV; Boye SE; Ye GJ; Iwabe S; Dufour VL; Marinho LF; Swider M; Kosyk MS; Sha J; Boye SL; Peterson JJ; Witherspoon CD; Alexander JJ; Ying GS; Shearman MS; Chulay JD; Hauswirth WW; Gamlin PD; Jacobson SG; Aguirre GD
    Mol Ther; 2017 Aug; 25(8):1866-1880. PubMed ID: 28566226
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Comprehensive Review of Mutations in the MERTK Proto-Oncogene.
    Parinot C; Nandrot EF
    Adv Exp Med Biol; 2016; 854():259-65. PubMed ID: 26427420
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gene therapy following subretinal AAV5 vector delivery is not affected by a previous intravitreal AAV5 vector administration in the partner eye.
    Li W; Kong F; Li X; Dai X; Liu X; Zheng Q; Wu R; Zhou X; Lü F; Chang B; Li Q; Hauswirth WW; Qu J; Pang JJ
    Mol Vis; 2009; 15():267-75. PubMed ID: 19190735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa.
    Gal A; Li Y; Thompson DA; Weir J; Orth U; Jacobson SG; Apfelstedt-Sylla E; Vollrath D
    Nat Genet; 2000 Nov; 26(3):270-1. PubMed ID: 11062461
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Toxicology and Pharmacology of an AAV Vector Expressing Codon-Optimized RPGR in RPGR-Deficient Rd9 Mice.
    Song C; Conlon TJ; Deng WT; Coleman KE; Zhu P; Plummer C; Mandapati S; Van Hoosear M; Green KB; Sonnentag P; Sharma AK; Timmers A; Robinson PM; Knop DR; Hauswirth WW; Chulay JD; Shearman MS; Ye GJ
    Hum Gene Ther Clin Dev; 2018 Dec; 29(4):188-197. PubMed ID: 30280954
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Toxicity and Efficacy Evaluation of an Adeno-Associated Virus Vector Expressing Codon-Optimized
    Dufour VL; Cideciyan AV; Ye GJ; Song C; Timmers A; Habecker PL; Pan W; Weinstein NM; Swider M; Durham AC; Ying GS; Robinson PM; Jacobson SG; Knop DR; Chulay JD; Shearman MS; Aguirre GD; Beltran WA
    Hum Gene Ther; 2020 Feb; 31(3-4):253-267. PubMed ID: 31910043
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Advancing Gene Therapy for PDE6A Retinitis Pigmentosa.
    Petersen-Jones SM; Occelli LM; Biel M; Michalakis S
    Adv Exp Med Biol; 2019; 1185():103-107. PubMed ID: 31884596
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat.
    D'Cruz PM; Yasumura D; Weir J; Matthes MT; Abderrahim H; LaVail MM; Vollrath D
    Hum Mol Genet; 2000 Mar; 9(4):645-51. PubMed ID: 10699188
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ectopic synaptogenesis during retinal degeneration in the royal college of surgeons rat.
    Peng YW; Senda T; Hao Y; Matsuno K; Wong F
    Neuroscience; 2003; 119(3):813-20. PubMed ID: 12809702
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.