BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 23696135)

  • 1. Stable expression of MutLγ in human cells reveals no specific response to mismatched DNA, but distinct recruitment to damage sites.
    Roesner LM; Mielke C; Fähnrich S; Merkhoffer Y; Dittmar KE; Drexler HG; Dirks WG
    J Cell Biochem; 2013 Oct; 114(10):2405-14. PubMed ID: 23696135
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
    Dai J; Sanchez A; Adam C; Ranjha L; Reginato G; Chervy P; Tellier-Lebegue C; Andreani J; Guérois R; Ropars V; Le Du MH; Maloisel L; Martini E; Legrand P; Thureau A; Cejka P; Borde V; Charbonnier JB
    Proc Natl Acad Sci U S A; 2021 Jun; 118(23):. PubMed ID: 34088835
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The first functional study of MLH3 mutations found in cancer patients.
    Korhonen MK; Vuorenmaa E; Nyström M
    Genes Chromosomes Cancer; 2008 Sep; 47(9):803-9. PubMed ID: 18521850
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.
    Chen PC; Kuraguchi M; Velasquez J; Wang Y; Yang K; Edwards R; Gillen D; Edelmann W; Kucherlapati R; Lipkin SM
    PLoS Genet; 2008 Jun; 4(6):e1000092. PubMed ID: 18551179
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Localization of MLH3 at the centrosomes.
    Roesner LM; Mielke C; Faehnrich S; Merkhoffer Y; Dittmar KE; Drexler HG; Dirks WG
    Int J Mol Sci; 2014 Aug; 15(8):13932-7. PubMed ID: 25116689
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A CRM1-dependent nuclear export pathway is involved in the regulation of MutLα subcellular localization.
    Brieger A; Adam R; Passmann S; Plotz G; Zeuzem S; Trojan J
    Genes Chromosomes Cancer; 2011 Feb; 50(2):59-70. PubMed ID: 21064154
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endonuclease activities of MutLα and its homologs in DNA mismatch repair.
    Kadyrova LY; Kadyrov FA
    DNA Repair (Amst); 2016 Feb; 38():42-49. PubMed ID: 26719141
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair.
    Claeys Bouuaert C; Keeney S
    PLoS Genet; 2017 May; 13(5):e1006722. PubMed ID: 28505149
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions.
    Ranjha L; Anand R; Cejka P
    J Biol Chem; 2014 Feb; 289(9):5674-86. PubMed ID: 24443562
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease.
    Kadyrov FA; Holmes SF; Arana ME; Lukianova OA; O'Donnell M; Kunkel TA; Modrich P
    J Biol Chem; 2007 Dec; 282(51):37181-90. PubMed ID: 17951253
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression analysis of MLH3, MLH1, and MSH4 in maturation arrest.
    Ferrás C; Fernandes S; Silva J; Barros A; Sousa M
    Reprod Sci; 2012 Jun; 19(6):587-96. PubMed ID: 22344730
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endonucleolytic function of MutLalpha in human mismatch repair.
    Kadyrov FA; Dzantiev L; Constantin N; Modrich P
    Cell; 2006 Jul; 126(2):297-308. PubMed ID: 16873062
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The PMS2 subunit of human MutLalpha contains a metal ion binding domain of the iron-dependent repressor protein family.
    Kosinski J; Plotz G; Guarné A; Bujnicki JM; Friedhoff P
    J Mol Biol; 2008 Oct; 382(3):610-27. PubMed ID: 18619468
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA Mismatch Repair Deficiency Promotes Genomic Instability in a Subset of Papillary Thyroid Cancers.
    Javid M; Sasanakietkul T; Nicolson NG; Gibson CE; Callender GG; Korah R; Carling T
    World J Surg; 2018 Feb; 42(2):358-366. PubMed ID: 29075860
    [TBL] [Abstract][Full Text] [Related]  

  • 15. GAA•TTC repeat expansion in human cells is mediated by mismatch repair complex MutLγ and depends upon the endonuclease domain in MLH3 isoform one.
    Halabi A; Fuselier KTB; Grabczyk E
    Nucleic Acids Res; 2018 May; 46(8):4022-4032. PubMed ID: 29529236
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Key role of phosphorylation sites in ATPase domain and Linker region of MLH1 for DNA binding and functionality of MutLα.
    Firnau MB; Plotz G; Zeuzem S; Brieger A
    Sci Rep; 2023 Aug; 13(1):12503. PubMed ID: 37532794
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A mutation in the putative MLH3 endonuclease domain confers a defect in both mismatch repair and meiosis in Saccharomyces cerevisiae.
    Nishant KT; Plys AJ; Alani E
    Genetics; 2008 Jun; 179(2):747-55. PubMed ID: 18505871
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans.
    Manhart CM; Ni X; White MA; Ortega J; Surtees JA; Alani E
    PLoS Biol; 2017 Apr; 15(4):e2001164. PubMed ID: 28453523
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BRCA1 activates a G2-M cell cycle checkpoint following 6-thioguanine-induced DNA mismatch damage.
    Yamane K; Schupp JE; Kinsella TJ
    Cancer Res; 2007 Jul; 67(13):6286-92. PubMed ID: 17616687
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA mismatch repair enzymes: genetic defects and autoimmunity.
    Muro Y; Sugiura K; Mimori T; Akiyama M
    Clin Chim Acta; 2015 Mar; 442():102-9. PubMed ID: 25619773
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.