BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 23696216)

  • 1. Deubiquitinase inhibition of 19S regulatory particles by 4-arylidene curcumin analog AC17 causes NF-κB inhibition and p53 reactivation in human lung cancer cells.
    Zhou B; Zuo Y; Li B; Wang H; Liu H; Wang X; Qiu X; Hu Y; Wen S; Du J; Bu X
    Mol Cancer Ther; 2013 Aug; 12(8):1381-92. PubMed ID: 23696216
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase.
    Yue X; Zuo Y; Ke H; Luo J; Lou L; Qin W; Wang Y; Liu Z; Chen D; Sun H; Zheng W; Zhu C; Wang R; Wen G; Du J; Zhou B; Bu X
    Biochem Pharmacol; 2017 Aug; 137():29-50. PubMed ID: 28476333
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cadmium pyrithione suppresses tumor growth in vitro and in vivo through inhibition of proteasomal deubiquitinase.
    Chen X; Wu J; Yang Q; Zhang X; Zhang P; Liao S; He Z; Wang X; Zhao C; Liu J
    Biometals; 2018 Feb; 31(1):29-43. PubMed ID: 29098502
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation.
    Wyke SM; Russell ST; Tisdale MJ
    Br J Cancer; 2004 Nov; 91(9):1742-50. PubMed ID: 15477867
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel nickel complex works as a proteasomal deubiquitinase inhibitor for cancer therapy.
    Zhao C; Chen X; Zang D; Lan X; Liao S; Yang C; Zhang P; Wu J; Li X; Liu N; Liao Y; Huang H; Shi X; Jiang L; Liu X; He Z; Dou QP; Wang X; Liu J
    Oncogene; 2016 Nov; 35(45):5916-5927. PubMed ID: 27086925
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and identification of new 4-arylidene curcumin analogues as potential anticancer agents targeting nuclear factor-κB signaling pathway.
    Qiu X; Du Y; Lou B; Zuo Y; Shao W; Huo Y; Huang J; Yu Y; Zhou B; Du J; Fu H; Bu X
    J Med Chem; 2010 Dec; 53(23):8260-73. PubMed ID: 21070043
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeted inhibition of the deubiquitinating enzymes, USP14 and UCHL5, induces proteotoxic stress and apoptosis in Waldenström macroglobulinaemia tumour cells.
    Chitta K; Paulus A; Akhtar S; Blake MK; Caulfield TR; Novak AJ; Ansell SM; Advani P; Ailawadhi S; Sher T; Linder S; Chanan-Khan A
    Br J Haematol; 2015 May; 169(3):377-90. PubMed ID: 25691154
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elevation of proteasomal substrate levels sensitizes cells to apoptosis induced by inhibition of proteasomal deubiquitinases.
    Sun C; Roboti P; Puumalainen MR; Fryknäs M; Wang X; D'Arcy P; Hult M; High S; Linder S; Swanton E
    PLoS One; 2014; 9(10):e108839. PubMed ID: 25286379
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hinokitiol copper complex inhibits proteasomal deubiquitination and induces paraptosis-like cell death in human cancer cells.
    Chen X; Zhang X; Chen J; Yang Q; Yang L; Xu D; Zhang P; Wang X; Liu J
    Eur J Pharmacol; 2017 Nov; 815():147-155. PubMed ID: 28887042
    [TBL] [Abstract][Full Text] [Related]  

  • 10. T63, a new 4-arylidene curcumin analogue, induces cell cycle arrest and apoptosis through activation of the reactive oxygen species-FOXO3a pathway in lung cancer cells.
    Liu H; Zhou BH; Qiu X; Wang HS; Zhang F; Fang R; Wang XF; Cai SH; Du J; Bu XZ
    Free Radic Biol Med; 2012 Dec; 53(12):2204-17. PubMed ID: 23085518
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2.
    Banerjee S; Ji C; Mayfield JE; Goel A; Xiao J; Dixon JE; Guo X
    Proc Natl Acad Sci U S A; 2018 Aug; 115(32):8155-8160. PubMed ID: 29987021
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Curcumin ameliorates the in vitro efficacy of carfilzomib in human multiple myeloma U266 cells targeting p53 and NF-κB pathways.
    Allegra A; Speciale A; Molonia MS; Guglielmo L; Musolino C; Ferlazzo G; Costa G; Saija A; Cimino F
    Toxicol In Vitro; 2018 Mar; 47():186-194. PubMed ID: 29223572
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stronger proteasomal inhibition and higher CHOP induction are responsible for more effective induction of paraptosis by dimethoxycurcumin than curcumin.
    Yoon MJ; Kang YJ; Lee JA; Kim IY; Kim MA; Lee YS; Park JH; Lee BY; Kim IA; Kim HS; Kim SA; Yoon AR; Yun CO; Kim EY; Lee K; Choi KS
    Cell Death Dis; 2014 Mar; 5(3):e1112. PubMed ID: 24625971
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases.
    Liu N; Liu C; Li X; Liao S; Song W; Yang C; Zhao C; Huang H; Guan L; Zhang P; Liu S; Hua X; Chen X; Zhou P; Lan X; Yi S; Wang S; Wang X; Dou QP; Liu J
    Sci Rep; 2014 Jun; 4():5240. PubMed ID: 24912524
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proteasome inhibition as a novel mechanism of the proapoptotic activity of γ-secretase inhibitor I in cutaneous T-cell lymphoma.
    Biskup E; Kamstrup MR; Manfé V; Gniadecki R
    Br J Dermatol; 2013 Mar; 168(3):504-12. PubMed ID: 23445313
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and evaluation of derivatives of the proteasome deubiquitinase inhibitor b-AP15.
    Wang X; D'Arcy P; Caulfield TR; Paulus A; Chitta K; Mohanty C; Gullbo J; Chanan-Khan A; Linder S
    Chem Biol Drug Des; 2015 Nov; 86(5):1036-48. PubMed ID: 25854145
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting of PP2Cδ By a Small Molecule C23 Inhibits High Glucose-Induced Breast Cancer Progression
    Wu K; Yu X; Huang Z; Zhu D; Yi X; Wu YL; Hao Q; Kemp KT; Elshimali Y; Iyer R; Nguyen KT; Zheng S; Chen G; Chen QH; Wang G; Vadgama JV; Wu Y
    Antioxid Redox Signal; 2019 Jun; 30(17):1983-1998. PubMed ID: 29808718
    [No Abstract]   [Full Text] [Related]  

  • 18. A binuclear complex constituted by diethyldithiocarbamate and copper(I) functions as a proteasome activity inhibitor in pancreatic cancer cultures and xenografts.
    Han J; Liu L; Yue X; Chang J; Shi W; Hua Y
    Toxicol Appl Pharmacol; 2013 Dec; 273(3):477-83. PubMed ID: 24060341
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of a novel curcumin analog P1 as potent inhibitor of the NF-κB signaling pathway with distinct mechanisms.
    Peng YM; Zheng JB; Zhou YB; Li J
    Acta Pharmacol Sin; 2013 Jul; 34(7):939-50. PubMed ID: 23603982
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deubiquitinase Inhibitor Auranofin Attenuated Cardiac Hypertrophy by Blocking NF-κB Activation.
    Hu M; Zhang Z; Liu B; Zhang S; Chai R; Chen X; Kong T; Zhang F; Zhang J; Liu S; Liu N
    Cell Physiol Biochem; 2018; 45(6):2421-2430. PubMed ID: 29554646
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.