242 related articles for article (PubMed ID: 23705993)
1. Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement.
Huang D; Li S; Xia M; Wen J; Jia X
Microb Cell Fact; 2013 May; 12():52. PubMed ID: 23705993
[TBL] [Abstract][Full Text] [Related]
2. Improvement of FK506 production via metabolic engineering-guided combinational strategies in Streptomyces tsukubaensis.
Wu QB; Zhang XY; Chen XA; Li YQ
Microb Cell Fact; 2021 Aug; 20(1):166. PubMed ID: 34425854
[TBL] [Abstract][Full Text] [Related]
3. Enhancement of FK506 production by engineering secondary pathways of Streptomyces tsukubaensis and exogenous feeding strategies.
Huang D; Xia M; Li S; Wen J; Jia X
J Ind Microbiol Biotechnol; 2013 Sep; 40(9):1023-37. PubMed ID: 23779221
[TBL] [Abstract][Full Text] [Related]
4. Improved FK506 production by the precursors and product-tolerant mutant of Streptomyces tsukubaensis based on genome shuffling and dynamic fed-batch strategies.
Du W; Huang D; Xia M; Wen J; Huang M
J Ind Microbiol Biotechnol; 2014 Jul; 41(7):1131-43. PubMed ID: 24788378
[TBL] [Abstract][Full Text] [Related]
5. Enhancement of rapamycin production by metabolic engineering in Streptomyces hygroscopicus based on genome-scale metabolic model.
Dang L; Liu J; Wang C; Liu H; Wen J
J Ind Microbiol Biotechnol; 2017 Feb; 44(2):259-270. PubMed ID: 27909940
[TBL] [Abstract][Full Text] [Related]
6. Combination of atmospheric and room temperature plasma (ARTP) mutagenesis, genome shuffling and dimethyl sulfoxide (DMSO) feeding to improve FK506 production in Streptomyces tsukubaensis.
Ye L; Ye R; Hu F; Wang G
Biotechnol Lett; 2021 Sep; 43(9):1809-1820. PubMed ID: 34160747
[TBL] [Abstract][Full Text] [Related]
7. FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis.
Goranovič D; Blažič M; Magdevska V; Horvat J; Kuščer E; Polak T; Santos-Aberturas J; Martínez-Castro M; Barreiro C; Mrak P; Kopitar G; Kosec G; Fujs S; Martín JF; Petković H
BMC Microbiol; 2012 Oct; 12():238. PubMed ID: 23083511
[TBL] [Abstract][Full Text] [Related]
8. Comparative proteomic and metabolomic analysis of Streptomyces tsukubaensis reveals the metabolic mechanism of FK506 overproduction by feeding soybean oil.
Wang J; Liu H; Huang D; Jin L; Wang C; Wen J
Appl Microbiol Biotechnol; 2017 Mar; 101(6):2447-2465. PubMed ID: 28175948
[TBL] [Abstract][Full Text] [Related]
9. Enhanced FK506 production in Streptomyces tsukubaensis by rational feeding strategies based on comparative metabolic profiling analysis.
Xia M; Huang D; Li S; Wen J; Jia X; Chen Y
Biotechnol Bioeng; 2013 Oct; 110(10):2717-30. PubMed ID: 23682004
[TBL] [Abstract][Full Text] [Related]
10. Combining metabolomics and network analysis to improve tacrolimus production in Streptomyces tsukubaensis using different exogenous feedings.
Wang C; Liu J; Liu H; Liang S; Wen J
J Ind Microbiol Biotechnol; 2017 Nov; 44(11):1527-1540. PubMed ID: 28776273
[TBL] [Abstract][Full Text] [Related]
11. Metabolic network model guided engineering ethylmalonyl-CoA pathway to improve ascomycin production in Streptomyces hygroscopicus var. ascomyceticus.
Wang J; Wang C; Song K; Wen J
Microb Cell Fact; 2017 Oct; 16(1):169. PubMed ID: 28974216
[TBL] [Abstract][Full Text] [Related]
12. FkbN and Tcs7 are pathway-specific regulators of the FK506 biosynthetic gene cluster in Streptomyces tsukubaensis L19.
Zhang XS; Luo HD; Tao Y; Wang YY; Jiang XH; Jiang H; Li YQ
J Ind Microbiol Biotechnol; 2016 Dec; 43(12):1693-1703. PubMed ID: 27757551
[TBL] [Abstract][Full Text] [Related]
13. Application of a combined approach involving classical random mutagenesis and metabolic engineering to enhance FK506 production in Streptomyces sp. RM7011.
Mo S; Lee SK; Jin YY; Oh CH; Suh JW
Appl Microbiol Biotechnol; 2013 Apr; 97(7):3053-62. PubMed ID: 23053074
[TBL] [Abstract][Full Text] [Related]
14. Draft genome of Streptomyces tsukubaensis NRRL 18488, the producer of the clinically important immunosuppressant tacrolimus (FK506).
Barreiro C; Prieto C; Sola-Landa A; Solera E; Martínez-Castro M; Pérez-Redondo R; García-Estrada C; Aparicio JF; Fernández-Martínez LT; Santos-Aberturas J; Salehi-Najafabadi Z; Rodríguez-García A; Tauch A; Martín JF
J Bacteriol; 2012 Jul; 194(14):3756-7. PubMed ID: 22740677
[TBL] [Abstract][Full Text] [Related]
15. Optimization of the precursor supply for an enhanced FK506 production in
Schulz S; Schall C; Stehle T; Breitmeyer C; Krysenko S; Mitulski A; Wohlleben W
Front Bioeng Biotechnol; 2022; 10():1067467. PubMed ID: 36466343
[TBL] [Abstract][Full Text] [Related]
16. Production improvement of FK506 in Streptomyces tsukubaensis by metabolic engineering strategy.
Chen HT; Zhang XY; Wu QB; Zhao QW; Chen XA; Li YQ
J Appl Microbiol; 2023 Jul; 134(7):. PubMed ID: 37429605
[TBL] [Abstract][Full Text] [Related]
17. Analysis of the Pho regulon in Streptomyces tsukubaensis.
Ordóñez-Robles M; Santos-Beneit F; Rodríguez-García A; Martín JF
Microbiol Res; 2017 Dec; 205():80-87. PubMed ID: 28942849
[TBL] [Abstract][Full Text] [Related]
18. Characterization of Discrete Phosphopantetheinyl Transferases in Streptomyces tsukubaensis L19 Unveils a Complicate Phosphopantetheinylation Network.
Wang YY; Zhang XS; Luo HD; Ren NN; Jiang XH; Jiang H; Li YQ
Sci Rep; 2016 Apr; 6():24255. PubMed ID: 27052100
[TBL] [Abstract][Full Text] [Related]
19. Roles of the crotonyl-CoA carboxylase/reductase homologues in acetate assimilation and biosynthesis of immunosuppressant FK506 in Streptomyces tsukubaensis.
Blažič M; Kosec G; Baebler Š; Gruden K; Petković H
Microb Cell Fact; 2015 Oct; 14():164. PubMed ID: 26466669
[TBL] [Abstract][Full Text] [Related]
20. Improvement of FK506 Production in the High-Yielding Strain Streptomyces sp. RM7011 by Engineering the Supply of Allylmalonyl-CoA Through a Combination of Genetic and Chemical Approach.
Mo S; Lee SK; Jin YY; Suh JW
J Microbiol Biotechnol; 2016 Feb; 26(2):233-40. PubMed ID: 26502733
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]