These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

368 related articles for article (PubMed ID: 23707768)

  • 1. Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1.
    Wang YM; Lin W; Chai SC; Wu J; Ong SS; Schuetz EG; Chen T
    Toxicol Appl Pharmacol; 2013 Oct; 272(1):96-107. PubMed ID: 23707768
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The protective effect of piperine on dextran sulfate sodium induced inflammatory bowel disease and its relation with pregnane X receptor activation.
    Hu D; Wang Y; Chen Z; Ma Z; You Q; Zhang X; Liang Q; Tan H; Xiao C; Tang X; Gao Y
    J Ethnopharmacol; 2015 Jul; 169():109-23. PubMed ID: 25907981
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thiazide-like diuretic drug metolazone activates human pregnane X receptor to induce cytochrome 3A4 and multidrug-resistance protein 1.
    Banerjee M; Chen T
    Biochem Pharmacol; 2014 Nov; 92(2):389-402. PubMed ID: 25181459
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells.
    Liu CL; Lim YP; Hu ML
    Mar Drugs; 2012 Jan; 10(1):242-257. PubMed ID: 22363234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.
    Ma X; Cheung C; Krausz KW; Shah YM; Wang T; Idle JR; Gonzalez FJ
    Drug Metab Dispos; 2008 Dec; 36(12):2506-12. PubMed ID: 18799805
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hepatitis B virus X protein co-activates pregnane X receptor to induce the cytochrome P450 3A4 enzyme, a potential implication in hepatocarcinogenesis.
    Niu Y; Wu Z; Shen Q; Song J; Luo Q; You H; Shi G; Qin W
    Dig Liver Dis; 2013 Dec; 45(12):1041-8. PubMed ID: 23891548
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR.
    Pondugula SR; Flannery PC; Abbott KL; Coleman ES; Mani S; Samuel T; Xie W
    Toxicol Lett; 2015 Feb; 232(3):580-9. PubMed ID: 25542144
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
    Song X; Xie M; Zhang H; Li Y; Sachdeva K; Yan B
    Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Camptothecin attenuates cytochrome P450 3A4 induction by blocking the activation of human pregnane X receptor.
    Chen Y; Tang Y; Robbins GT; Nie D
    J Pharmacol Exp Ther; 2010 Sep; 334(3):999-1008. PubMed ID: 20504912
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines.
    Pfrunder A; Gutmann H; Beglinger C; Drewe J
    J Pharm Pharmacol; 2003 Jan; 55(1):59-66. PubMed ID: 12625868
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro.
    Feng D; Tang T; Fan R; Luo J; Cui H; Wang Y; Gan P
    BMC Complement Altern Med; 2018 Dec; 18(1):345. PubMed ID: 30594244
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
    Gupta A; Mugundu GM; Desai PB; Thummel KE; Unadkat JD
    Drug Metab Dispos; 2008 Jun; 36(6):1172-80. PubMed ID: 18332086
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion.
    Masuyama H; Suwaki N; Tateishi Y; Nakatsukasa H; Segawa T; Hiramatsu Y
    Mol Endocrinol; 2005 May; 19(5):1170-80. PubMed ID: 15650019
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells.
    Martin P; Riley R; Back DJ; Owen A
    Br J Pharmacol; 2008 Feb; 153(4):805-19. PubMed ID: 18037906
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of cytochrome P450 3A4 and P-glycoprotein by the isoxazolyl-penicillin antibiotic flucloxacillin.
    Huwyler J; Wright MB; Gutmann H; Drewe J
    Curr Drug Metab; 2006 Feb; 7(2):119-26. PubMed ID: 16472102
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression levels and activation of a PXR variant are directly related to drug resistance in osteosarcoma cell lines.
    Mensah-Osman EJ; Thomas DG; Tabb MM; Larios JM; Hughes DP; Giordano TJ; Lizyness ML; Rae JM; Blumberg B; Hollenberg PF; Baker LH
    Cancer; 2007 Mar; 109(5):957-65. PubMed ID: 17279585
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anticancer agents in ovarian cancer cells.
    Masuyama H; Nakamura K; Nobumoto E; Hiramatsu Y
    Int J Oncol; 2016 Sep; 49(3):1211-20. PubMed ID: 27572875
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways.
    Li Y; Wang Q; Yao X; Li Y
    Eur J Pharmacol; 2010 Aug; 640(1-3):46-54. PubMed ID: 20580705
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of piperine and quercetin alone or in combination with marbofloxacin on CYP3A37 and MDR1 mRNA expression levels in broiler chickens.
    Patel HB; Patel UD; Mathapati BS; Modi CM
    Res Vet Sci; 2019 Oct; 126():178-183. PubMed ID: 31539794
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.