204 related articles for article (PubMed ID: 23711097)
1. Cardiac glycosides correct aberrant splicing of IKBKAP-encoded mRNA in familial dysautonomia derived cells by suppressing expression of SRSF3.
Liu B; Anderson SL; Qiu J; Rubin BY
FEBS J; 2013 Aug; 280(15):3632-46. PubMed ID: 23711097
[TBL] [Abstract][Full Text] [Related]
2. Nutraceutical-mediated restoration of wild-type levels of IKBKAP-encoded IKAP protein in familial dysautonomia-derived cells.
Anderson SL; Liu B; Qiu J; Sturm AJ; Schwartz JA; Peters AJ; Sullivan KA; Rubin BY
Mol Nutr Food Res; 2012 Apr; 56(4):570-9. PubMed ID: 22495984
[TBL] [Abstract][Full Text] [Related]
3. RBM24 promotes U1 snRNP recognition of the mutated 5' splice site in the
Ohe K; Yoshida M; Nakano-Kobayashi A; Hosokawa M; Sako Y; Sakuma M; Okuno Y; Usui T; Ninomiya K; Nojima T; Kataoka N; Hagiwara M
RNA; 2017 Sep; 23(9):1393-1403. PubMed ID: 28592461
[TBL] [Abstract][Full Text] [Related]
4. EGCG corrects aberrant splicing of IKAP mRNA in cells from patients with familial dysautonomia.
Anderson SL; Qiu J; Rubin BY
Biochem Biophys Res Commun; 2003 Oct; 310(2):627-33. PubMed ID: 14521957
[TBL] [Abstract][Full Text] [Related]
5. Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia.
Anderson SL; Qiu J; Rubin BY
Biochem Biophys Res Commun; 2003 Jun; 306(1):303-9. PubMed ID: 12788105
[TBL] [Abstract][Full Text] [Related]
6. Sensory and autonomic deficits in a new humanized mouse model of familial dysautonomia.
Morini E; Dietrich P; Salani M; Downs HM; Wojtkiewicz GR; Alli S; Brenner A; Nilbratt M; LeClair JW; Oaklander AL; Slaugenhaupt SA; Dragatsis I
Hum Mol Genet; 2016 Mar; 25(6):1116-28. PubMed ID: 26769677
[TBL] [Abstract][Full Text] [Related]
7. Multiple effects of digoxin on subsets of cancer-associated genes through the alternative splicing pathway.
Lu GY; Liu ST; Huang SM; Chang YL; Lin WS
Biochimie; 2014 Nov; 106():131-9. PubMed ID: 25193633
[TBL] [Abstract][Full Text] [Related]
8. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing.
Gold-von Simson G; Goldberg JD; Rolnitzky LM; Mull J; Leyne M; Voustianiouk A; Slaugenhaupt SA; Axelrod FB
Pediatr Res; 2009 Mar; 65(3):341-6. PubMed ID: 19033881
[TBL] [Abstract][Full Text] [Related]
9. Carnosol, a diterpene present in rosemary, increases ELP1 levels in familial dysautonomia patient-derived cells and healthy adults: a possible therapy for FD.
Anderson SL; Fasih-Ahmad F; Evans AJ; Rubin BY
Hum Mol Genet; 2022 Oct; 31(20):3521-3538. PubMed ID: 35708500
[TBL] [Abstract][Full Text] [Related]
10. Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia.
Yoshida M; Kataoka N; Miyauchi K; Ohe K; Iida K; Yoshida S; Nojima T; Okuno Y; Onogi H; Usui T; Takeuchi A; Hosoya T; Suzuki T; Hagiwara M
Proc Natl Acad Sci U S A; 2015 Mar; 112(9):2764-9. PubMed ID: 25675486
[TBL] [Abstract][Full Text] [Related]
11. Blocking of an intronic splicing silencer completely rescues IKBKAP exon 20 splicing in familial dysautonomia patient cells.
Bruun GH; Bang JMV; Christensen LL; Brøner S; Petersen USS; Guerra B; Grønning AGB; Doktor TK; Andresen BS
Nucleic Acids Res; 2018 Sep; 46(15):7938-7952. PubMed ID: 29762696
[TBL] [Abstract][Full Text] [Related]
12. Antisense oligonucleotides correct the familial dysautonomia splicing defect in IKBKAP transgenic mice.
Sinha R; Kim YJ; Nomakuchi T; Sahashi K; Hua Y; Rigo F; Bennett CF; Krainer AR
Nucleic Acids Res; 2018 Jun; 46(10):4833-4844. PubMed ID: 29672717
[TBL] [Abstract][Full Text] [Related]
13. Therapeutic potential and mechanism of kinetin as a treatment for the human splicing disease familial dysautonomia.
Hims MM; Ibrahim EC; Leyne M; Mull J; Liu L; Lazaro C; Shetty RS; Gill S; Gusella JF; Reed R; Slaugenhaupt SA
J Mol Med (Berl); 2007 Feb; 85(2):149-61. PubMed ID: 17206408
[TBL] [Abstract][Full Text] [Related]
14. Tissue-specific reduction in splicing efficiency of IKBKAP due to the major mutation associated with familial dysautonomia.
Cuajungco MP; Leyne M; Mull J; Gill SP; Lu W; Zagzag D; Axelrod FB; Maayan C; Gusella JF; Slaugenhaupt SA
Am J Hum Genet; 2003 Mar; 72(3):749-58. PubMed ID: 12577200
[TBL] [Abstract][Full Text] [Related]
15. Weak definition of IKBKAP exon 20 leads to aberrant splicing in familial dysautonomia.
Ibrahim EC; Hims MM; Shomron N; Burge CB; Slaugenhaupt SA; Reed R
Hum Mutat; 2007 Jan; 28(1):41-53. PubMed ID: 16964593
[TBL] [Abstract][Full Text] [Related]
16. Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence.
Tang Y; Horikawa I; Ajiro M; Robles AI; Fujita K; Mondal AM; Stauffer JK; Zheng ZM; Harris CC
Oncogene; 2013 May; 32(22):2792-8. PubMed ID: 22777358
[TBL] [Abstract][Full Text] [Related]
17. Phosphatidylserine increases IKBKAP levels in a humanized knock-in IKBKAP mouse model.
Bochner R; Ziv Y; Zeevi D; Donyo M; Abraham L; Ashery-Padan R; Ast G
Hum Mol Genet; 2013 Jul; 22(14):2785-94. PubMed ID: 23515154
[TBL] [Abstract][Full Text] [Related]
18. Proteasome inhibitors to alleviate aberrant IKBKAP mRNA splicing and low IKAP/hELP1 synthesis in familial dysautonomia.
Hervé M; Ibrahim EC
Neurobiol Dis; 2017 Jul; 103():113-122. PubMed ID: 28404519
[TBL] [Abstract][Full Text] [Related]
19. Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia.
Ajiro M; Awaya T; Kim YJ; Iida K; Denawa M; Tanaka N; Kurosawa R; Matsushima S; Shibata S; Sakamoto T; Studer L; Krainer AR; Hagiwara M
Nat Commun; 2021 Jul; 12(1):4507. PubMed ID: 34301951
[TBL] [Abstract][Full Text] [Related]
20. Olfactory stem cells, a new cellular model for studying molecular mechanisms underlying familial dysautonomia.
Boone N; Loriod B; Bergon A; Sbai O; Formisano-Tréziny C; Gabert J; Khrestchatisky M; Nguyen C; Féron F; Axelrod FB; Ibrahim EC
PLoS One; 2010 Dec; 5(12):e15590. PubMed ID: 21187979
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]