These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 23719920)

  • 21. Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin.
    Wang H; Lim PJ; Yin C; Rieckher M; Vogel BE; Monteiro MJ
    Hum Mol Genet; 2006 Mar; 15(6):1025-41. PubMed ID: 16461334
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Fragments of HdhQ150 mutant huntingtin form a soluble oligomer pool that declines with aggregate deposition upon aging.
    Marcellin D; Abramowski D; Young D; Richter J; Weiss A; Marcel A; Maassen J; Kauffmann M; Bibel M; Shimshek DR; Faull RL; Bates GP; Kuhn RR; Van der Putten PH; Schmid P; Lotz GP
    PLoS One; 2012; 7(9):e44457. PubMed ID: 22984513
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mutational analysis implicates the amyloid fibril as the toxic entity in Huntington's disease.
    Drombosky KW; Rode S; Kodali R; Jacob TC; Palladino MJ; Wetzel R
    Neurobiol Dis; 2018 Dec; 120():126-138. PubMed ID: 30171891
    [TBL] [Abstract][Full Text] [Related]  

  • 24. N-Terminal Fragments of Huntingtin Longer than Residue 170 form Visible Aggregates Independently to Polyglutamine Expansion.
    Chen MZ; Mok SA; Ormsby AR; Muchowski PJ; Hatters DM
    J Huntingtons Dis; 2017; 6(1):79-91. PubMed ID: 28339398
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System.
    Pace JB; Huang NN; Séguin JP; Esquina C; Olin E; Zhu G; Carr G
    J Vis Exp; 2021 Dec; (178):. PubMed ID: 34958078
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mass spectrometric identification of novel posttranslational modification sites in Huntingtin.
    Dong G; Callegari E; Gloeckner CJ; Ueffing M; Wang H
    Proteomics; 2012 Jun; 12(12):2060-4. PubMed ID: 22623107
    [TBL] [Abstract][Full Text] [Related]  

  • 27. PolyQ-Expanded Mutant Huntingtin Forms Inclusion Body Following Transient Cold Shock in a Two-Step Aggregation Mechanism.
    Castro E Costa AR; Mysore S; Paruchuri P; Chen KY; Liu AY
    ACS Chem Neurosci; 2023 Jan; 14(2):277-288. PubMed ID: 36574489
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Formation of morphologically similar globular aggregates from diverse aggregation-prone proteins in mammalian cells.
    Mukai H; Isagawa T; Goyama E; Tanaka S; Bence NF; Tamura A; Ono Y; Kopito RR
    Proc Natl Acad Sci U S A; 2005 Aug; 102(31):10887-92. PubMed ID: 16040812
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Pramipexole reduces soluble mutant huntingtin and protects striatal neurons through dopamine D3 receptors in a genetic model of Huntington's disease.
    Luis-Ravelo D; Estévez-Silva H; Barroso-Chinea P; Afonso-Oramas D; Salas-Hernández J; Rodríguez-Núñez J; Acevedo-Arozena A; Marcellino D; González-Hernández T
    Exp Neurol; 2018 Jan; 299(Pt A):137-147. PubMed ID: 29056363
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models.
    Ehrnhoefer DE; Duennwald M; Markovic P; Wacker JL; Engemann S; Roark M; Legleiter J; Marsh JL; Thompson LM; Lindquist S; Muchowski PJ; Wanker EE
    Hum Mol Genet; 2006 Sep; 15(18):2743-51. PubMed ID: 16893904
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation.
    Tashiro E; Zako T; Muto H; Itoo Y; Sörgjerd K; Terada N; Abe A; Miyazawa M; Kitamura A; Kitaura H; Kubota H; Maeda M; Momoi T; Iguchi-Ariga SM; Kinjo M; Ariga H
    J Biol Chem; 2013 Jul; 288(27):19958-72. PubMed ID: 23720755
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Modulation of mutant Huntingtin aggregates and toxicity by human myeloid leukemia factors.
    Banerjee M; Datta M; Bhattacharyya NP
    Int J Biochem Cell Biol; 2017 Jan; 82():1-9. PubMed ID: 27840155
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Recombinant Adeno Associated Viral (AAV) vector type 9 delivery of Ex1-Q138-mutant huntingtin in the rat striatum as a short-time model for in vivo studies in drug discovery.
    Ceccarelli I; Fiengo P; Remelli R; Miragliotta V; Rossini L; Biotti I; Cappelli A; Petricca L; La Rosa S; Caricasole A; Pollio G; Scali C
    Neurobiol Dis; 2016 Feb; 86():41-51. PubMed ID: 26626080
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Aggregation landscapes of Huntingtin exon 1 protein fragments and the critical repeat length for the onset of Huntington's disease.
    Chen M; Wolynes PG
    Proc Natl Acad Sci U S A; 2017 Apr; 114(17):4406-4411. PubMed ID: 28400517
    [TBL] [Abstract][Full Text] [Related]  

  • 35. N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
    Orr AL; Li S; Wang CE; Li H; Wang J; Rong J; Xu X; Mastroberardino PG; Greenamyre JT; Li XJ
    J Neurosci; 2008 Mar; 28(11):2783-92. PubMed ID: 18337408
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Pharmacological activation of Sirt1 ameliorates polyglutamine-induced toxicity through the regulation of autophagy.
    Shin BH; Lim Y; Oh HJ; Park SM; Lee SK; Ahnn J; Kim DH; Song WK; Kwak TH; Park WJ
    PLoS One; 2013; 8(6):e64953. PubMed ID: 23762270
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Slow amyloid nucleation via α-helix-rich oligomeric intermediates in short polyglutamine-containing huntingtin fragments.
    Jayaraman M; Kodali R; Sahoo B; Thakur AK; Mayasundari A; Mishra R; Peterson CB; Wetzel R
    J Mol Biol; 2012 Feb; 415(5):881-99. PubMed ID: 22178474
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity.
    Khoshnan A; Ko J; Patterson PH
    Proc Natl Acad Sci U S A; 2002 Jan; 99(2):1002-7. PubMed ID: 11792860
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Mutant Huntingtin Is Secreted via a Late Endosomal/Lysosomal Unconventional Secretory Pathway.
    Trajkovic K; Jeong H; Krainc D
    J Neurosci; 2017 Sep; 37(37):9000-9012. PubMed ID: 28821645
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography.
    Darrow MC; Sergeeva OA; Isas JM; Galaz-Montoya JG; King JA; Langen R; Schmid MF; Chiu W
    J Biol Chem; 2015 Jul; 290(28):17451-61. PubMed ID: 25995452
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.