These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
1247 related articles for article (PubMed ID: 23723238)
1. A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Bar-Peled L; Chantranupong L; Cherniack AD; Chen WW; Ottina KA; Grabiner BC; Spear ED; Carter SL; Meyerson M; Sabatini DM Science; 2013 May; 340(6136):1100-6. PubMed ID: 23723238 [TBL] [Abstract][Full Text] [Related]
3. SZT2 dictates GATOR control of mTORC1 signalling. Peng M; Yin N; Li MO Nature; 2017 Mar; 543(7645):433-437. PubMed ID: 28199315 [TBL] [Abstract][Full Text] [Related]
4. Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes. Shen K; Huang RK; Brignole EJ; Condon KJ; Valenstein ML; Chantranupong L; Bomaliyamu A; Choe A; Hong C; Yu Z; Sabatini DM Nature; 2018 Apr; 556(7699):64-69. PubMed ID: 29590090 [TBL] [Abstract][Full Text] [Related]
5. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Wolfson RL; Chantranupong L; Wyant GA; Gu X; Orozco JM; Shen K; Condon KJ; Petri S; Kedir J; Scaria SM; Abu-Remaileh M; Frankel WN; Sabatini DM Nature; 2017 Mar; 543(7645):438-442. PubMed ID: 28199306 [TBL] [Abstract][Full Text] [Related]
6. Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia. Weckhuysen S; Marsan E; Lambrecq V; Marchal C; Morin-Brureau M; An-Gourfinkel I; Baulac M; Fohlen M; Kallay Zetchi C; Seeck M; de la Grange P; Dermaut B; Meurs A; Thomas P; Chassoux F; Leguern E; Picard F; Baulac S Epilepsia; 2016 Jun; 57(6):994-1003. PubMed ID: 27173016 [TBL] [Abstract][Full Text] [Related]
7. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1. Tsun ZY; Bar-Peled L; Chantranupong L; Zoncu R; Wang T; Kim C; Spooner E; Sabatini DM Mol Cell; 2013 Nov; 52(4):495-505. PubMed ID: 24095279 [TBL] [Abstract][Full Text] [Related]
8. The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1. Chantranupong L; Wolfson RL; Orozco JM; Saxton RA; Scaria SM; Bar-Peled L; Spooner E; Isasa M; Gygi SP; Sabatini DM Cell Rep; 2014 Oct; 9(1):1-8. PubMed ID: 25263562 [TBL] [Abstract][Full Text] [Related]
9. Rag-Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathway. Valenstein ML; Lalgudi PV; Gu X; Kedir JF; Taylor MS; Chivukula RR; Sabatini DM Proc Natl Acad Sci U S A; 2024 Aug; 121(35):e2322755121. PubMed ID: 39163330 [TBL] [Abstract][Full Text] [Related]
10. Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation. Kwak SS; Kang KH; Kim S; Lee S; Lee JH; Kim JW; Byun B; Meadows GG; Joe CO Cell Signal; 2016 Feb; 28(2):32-41. PubMed ID: 26582740 [TBL] [Abstract][Full Text] [Related]
11. Sestrins inhibit mTORC1 kinase activation through the GATOR complex. Parmigiani A; Nourbakhsh A; Ding B; Wang W; Kim YC; Akopiants K; Guan KL; Karin M; Budanov AV Cell Rep; 2014 Nov; 9(4):1281-91. PubMed ID: 25457612 [TBL] [Abstract][Full Text] [Related]
13. Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism. Egri SB; Ouch C; Chou HT; Yu Z; Song K; Xu C; Shen K Mol Cell; 2022 May; 82(10):1836-1849.e5. PubMed ID: 35338845 [TBL] [Abstract][Full Text] [Related]
14. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling. Peng M; Yin N; Li MO Cell; 2014 Sep; 159(1):122-133. PubMed ID: 25259925 [TBL] [Abstract][Full Text] [Related]
15. Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases. Petit CS; Roczniak-Ferguson A; Ferguson SM J Cell Biol; 2013 Sep; 202(7):1107-22. PubMed ID: 24081491 [TBL] [Abstract][Full Text] [Related]
16. Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells. Doxsey DD; Tettoni SD; Egri SB; Shen K J Biol Chem; 2023 Jul; 299(7):104880. PubMed ID: 37269949 [TBL] [Abstract][Full Text] [Related]
17. The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation. Deng L; Jiang C; Chen L; Jin J; Wei J; Zhao L; Chen M; Pan W; Xu Y; Chu H; Wang X; Ge X; Li D; Liao L; Liu M; Li L; Wang P Mol Cell; 2015 Jun; 58(5):804-18. PubMed ID: 25936802 [TBL] [Abstract][Full Text] [Related]
18. Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1. Bar-Peled L; Schweitzer LD; Zoncu R; Sabatini DM Cell; 2012 Sep; 150(6):1196-208. PubMed ID: 22980980 [TBL] [Abstract][Full Text] [Related]
20. Sestrin2 inhibits mTORC1 through modulation of GATOR complexes. Kim JS; Ro SH; Kim M; Park HW; Semple IA; Park H; Cho US; Wang W; Guan KL; Karin M; Lee JH Sci Rep; 2015 Mar; 5():9502. PubMed ID: 25819761 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]