These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 23725514)

  • 1. Discovery of small-molecule modulators of the Sonic Hedgehog pathway.
    Schaefer GI; Perez JR; Duvall JR; Stanton BZ; Shamji AF; Schreiber SL
    J Am Chem Soc; 2013 Jul; 135(26):9675-80. PubMed ID: 23725514
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling.
    Petrova E; Rios-Esteves J; Ouerfelli O; Glickman JF; Resh MD
    Nat Chem Biol; 2013 Apr; 9(4):247-9. PubMed ID: 23416332
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of Hedgehog Antagonists for Cancer Therapy.
    Khatra H; Bose C; Sinha S
    Curr Med Chem; 2017; 24(19):2033-2058. PubMed ID: 28302010
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small-molecule inhibitors of the hedgehog signaling pathway as cancer therapeutics.
    Peukert S; Miller-Moslin K
    ChemMedChem; 2010 Apr; 5(4):500-12. PubMed ID: 20229564
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of anticancer agents targeting the Hedgehog signaling.
    Zhang X; Tian Y; Yang Y; Hao J
    Cell Mol Life Sci; 2017 Aug; 74(15):2773-2782. PubMed ID: 28314894
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of the performance of a small molecule library based on diverse tropane-related scaffolds.
    Lowe RA; Taylor D; Chibale K; Nelson A; Marsden SP
    Bioorg Med Chem; 2020 May; 28(9):115442. PubMed ID: 32209295
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization and Discovery of a Selective Small-Molecule Modulator of Mitochondrial Complex I Targeting a Unique Binding Site.
    Green JC; Jiang Y; He L; Xu Y; Sun D; Keoprasert T; Nelson C; Oh U; Lesnefsky EJ; Kellogg GE; Chen Q; Zhang S
    J Med Chem; 2020 Oct; 63(20):11819-11830. PubMed ID: 32945676
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and Evolution of a Macrocyclic Peptide Inhibitor of the Sonic Hedgehog/Patched Interaction.
    Owens AE; de Paola I; Hansen WA; Liu YW; Khare SD; Fasan R
    J Am Chem Soc; 2017 Sep; 139(36):12559-12568. PubMed ID: 28759213
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.
    Němec V; Hylsová M; Maier L; Flegel J; Sievers S; Ziegler S; Schröder M; Berger BT; Chaikuad A; Valčíková B; Uldrijan S; Drápela S; Souček K; Waldmann H; Knapp S; Paruch K
    Angew Chem Int Ed Engl; 2019 Jan; 58(4):1062-1066. PubMed ID: 30569600
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent small molecule Hedgehog agonists induce VEGF expression in vitro.
    Seifert K; Büttner A; Rigol S; Eilert N; Wandel E; Giannis A
    Bioorg Med Chem; 2012 Nov; 20(21):6465-81. PubMed ID: 22985958
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based discovery of potent and selective small-molecule inhibitors targeting signal transducer and activator of transcription 3 (STAT3).
    Huang Q; Zhong Y; Li B; Ouyang S; Deng L; Mo J; Shi S; Lv N; Wu R; Liu P; Hu W; Zhang X; Wang Y
    Eur J Med Chem; 2021 Oct; 221():113525. PubMed ID: 34000483
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small-molecule modulators of the Sonic Hedgehog signaling pathway.
    Stanton BZ; Peng LF
    Mol Biosyst; 2010 Jan; 6(1):44-54. PubMed ID: 20024066
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of novel inhibitors of signal transducer and activator of transcription 3 (STAT3) signaling pathway by virtual screening.
    Zhang M; Zhu W; Li Y
    Eur J Med Chem; 2013 Apr; 62():301-10. PubMed ID: 23376248
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the Hedgehog Signaling Pathway with Small Molecules from Natural Sources.
    Petricci E; Manetti F
    Curr Med Chem; 2015; 22(35):4058-90. PubMed ID: 26337106
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway.
    Büttner A; Seifert K; Cottin T; Sarli V; Tzagkaroulaki L; Scholz S; Giannis A
    Bioorg Med Chem; 2009 Jul; 17(14):4943-54. PubMed ID: 19541490
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of Small Molecule Inhibitors Targeting the Sonic Hedgehog.
    Yun T; Wang J; Yang J; Huang W; Lai L; Tan W; Liu Y
    Front Chem; 2020; 8():498. PubMed ID: 32612978
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A molecular dynamics approach to identify an oxysterol-based hedgehog pathway inhibitor.
    Dash RC; Maschinot CR; Hadden MK
    Biochim Biophys Acta Gen Subj; 2017 Feb; 1861(2):168-177. PubMed ID: 27825830
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New developments in the discovery of small molecule Hedgehog pathway antagonists.
    Tremblay MR; McGovern K; Read MA; Castro AC
    Curr Opin Chem Biol; 2010 Jun; 14(3):428-35. PubMed ID: 20399136
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hedgehog pathway agonism: therapeutic potential and small-molecule development.
    Hadden MK
    ChemMedChem; 2014 Jan; 9(1):27-37. PubMed ID: 24203435
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of USP7 small-molecule allosteric inhibitors.
    Engström O; Belda O; Kullman-Magnusson M; Rapp M; Böhm K; Paul R; Henderson I; Derbyshire D; Karlström S; Parkes KEB; Zhao H
    Bioorg Med Chem Lett; 2020 Oct; 30(20):127471. PubMed ID: 32781219
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.