BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 23727242)

  • 1. FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
    Mead AJ; Kharazi S; Atkinson D; Macaulay I; Pecquet C; Loughran S; Lutteropp M; Woll P; Chowdhury O; Luc S; Buza-Vidas N; Ferry H; Clark SA; Goardon N; Vyas P; Constantinescu SN; Sitnicka E; Nerlov C; Jacobsen SE
    Cell Rep; 2013 Jun; 3(6):1766-76. PubMed ID: 23727242
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to
    Porter SN; Cluster AS; Yang W; Busken KA; Patel RM; Ryoo J; Magee JA
    Elife; 2016 Nov; 5():. PubMed ID: 27879203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD.
    Rocnik JL; Okabe R; Yu JC; Lee BH; Giese N; Schenkein DP; Gilliland DG
    Blood; 2006 Aug; 108(4):1339-45. PubMed ID: 16627759
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Potent co-operation between the NUP98-NSD1 fusion and the FLT3-ITD mutation in acute myeloid leukemia induction.
    Thanasopoulou A; Tzankov A; Schwaller J
    Haematologica; 2014 Sep; 99(9):1465-71. PubMed ID: 24951466
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development.
    Böiers C; Buza-Vidas N; Jensen CT; Pronk CJ; Kharazi S; Wittmann L; Sitnicka E; Hultquist A; Jacobsen SE
    Blood; 2010 Jun; 115(24):5061-8. PubMed ID: 20393130
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NF-κB/STAT5/miR-155 network targets PU.1 in FLT3-ITD-driven acute myeloid leukemia.
    Gerloff D; Grundler R; Wurm AA; Bräuer-Hartmann D; Katzerke C; Hartmann JU; Madan V; Müller-Tidow C; Duyster J; Tenen DG; Niederwieser D; Behre G
    Leukemia; 2015 Mar; 29(3):535-47. PubMed ID: 25092144
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3.
    Lin DC; Yin T; Koren-Michowitz M; Ding LW; Gueller S; Gery S; Tabayashi T; Bergholz U; Kazi JU; Rönnstrand L; Stocking C; Koeffler HP
    Blood; 2012 Oct; 120(16):3310-7. PubMed ID: 22942183
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heterogeneity of Flt3-expressing multipotent progenitors in mouse bone marrow.
    Lai AY; Lin SM; Kondo M
    J Immunol; 2005 Oct; 175(8):5016-23. PubMed ID: 16210604
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lineage-specific STAT5 target gene activation in hematopoietic progenitor cells predicts the FLT3(+)-mediated leukemic phenotype.
    Müller TA; Grundler R; Istvanffy R; Rudelius M; Hennighausen L; Illert AL; Duyster J
    Leukemia; 2016 Aug; 30(8):1725-33. PubMed ID: 27046463
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model.
    Reckzeh K; Bereshchenko O; Mead A; Rehn M; Kharazi S; Jacobsen SE; Nerlov C; Cammenga J
    Leukemia; 2012 Jul; 26(7):1527-36. PubMed ID: 22318449
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FLT3 in lineage specification and plasticity.
    Greenblatt S; Small D
    Oncotarget; 2012 May; 3(5):576-80. PubMed ID: 22643831
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Flk2/Flt3 promotes both myeloid and lymphoid development by expanding non-self-renewing multipotent hematopoietic progenitor cells.
    Beaudin AE; Boyer SW; Forsberg EC
    Exp Hematol; 2014 Mar; 42(3):218-229.e4. PubMed ID: 24333663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Elevated frequencies of leukemic myeloid and plasmacytoid dendritic cells in acute myeloid leukemia with the FLT3 internal tandem duplication.
    Rickmann M; Krauter J; Stamer K; Heuser M; Salguero G; Mischak-Weissinger E; Ganser A; Stripecke R
    Ann Hematol; 2011 Sep; 90(9):1047-58. PubMed ID: 21520003
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of Flt3⁺CD150⁻ myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential.
    Chi AW; Chavez A; Xu L; Weber BN; Shestova O; Schaffer A; Wertheim G; Pear WS; Izon D; Bhandoola A
    Blood; 2011 Sep; 118(10):2723-32. PubMed ID: 21791413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Features of Ras activation by a mislocalized oncogenic tyrosine kinase: FLT3 ITD signals through K-Ras at the plasma membrane of acute myeloid leukemia cells.
    Köthe S; Müller JP; Böhmer SA; Tschongov T; Fricke M; Koch S; Thiede C; Requardt RP; Rubio I; Böhmer FD
    J Cell Sci; 2013 Oct; 126(Pt 20):4746-55. PubMed ID: 23943874
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Internal tandem duplication mutations in the tyrosine kinase domain of FLT3 display a higher oncogenic potential than the activation loop D835Y mutation.
    Marhäll A; Heidel F; Fischer T; Rönnstrand L
    Ann Hematol; 2018 May; 97(5):773-780. PubMed ID: 29372308
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphoproteome analyses reveal specific implications of Hcls1, p21-activated kinase 1 and Ezrin in proliferation of a myeloid progenitor cell line downstream of wild-type and ITD mutant Fms-like tyrosine kinase 3 receptors.
    Habif G; Grasset MF; Kieffer-Jaquinod S; Kuhn L; Mouchiroud G; Gobert-Gosse S
    J Proteomics; 2013 Jan; 78():231-44. PubMed ID: 23017497
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Constitutive activation of Flt3 and STAT5A enhances self-renewal and alters differentiation of hematopoietic stem cells.
    Moore MA; Dorn DC; Schuringa JJ; Chung KY; Morrone G
    Exp Hematol; 2007 Apr; 35(4 Suppl 1):105-16. PubMed ID: 17379095
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice.
    Li L; Bailey E; Greenblatt S; Huso D; Small D
    Blood; 2011 Nov; 118(18):4935-45. PubMed ID: 21908433
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.
    Brandts CH; Sargin B; Rode M; Biermann C; Lindtner B; Schwäble J; Buerger H; Müller-Tidow C; Choudhary C; McMahon M; Berdel WE; Serve H
    Cancer Res; 2005 Nov; 65(21):9643-50. PubMed ID: 16266983
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.