BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 23728337)

  • 1. EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180.
    Feng H; Hu B; Vuori K; Sarkaria JN; Furnari FB; Cavenee WK; Cheng SY
    Oncogene; 2014 May; 33(19):2504-12. PubMed ID: 23728337
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.
    Feng H; Li Y; Yin Y; Zhang W; Hou Y; Zhang L; Li Z; Xie B; Gao WQ; Sarkaria JN; Raizer JJ; James CD; Parsa AT; Hu B; Cheng SY
    Neuro Oncol; 2015 Jun; 17(6):832-42. PubMed ID: 25468898
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis.
    Feng H; Hu B; Jarzynka MJ; Li Y; Keezer S; Johns TG; Tang CK; Hamilton RL; Vuori K; Nishikawa R; Sarkaria JN; Fenton T; Cheng T; Furnari FB; Cavenee WK; Cheng SY
    Proc Natl Acad Sci U S A; 2012 Feb; 109(8):3018-23. PubMed ID: 22323579
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans.
    Feng H; Hu B; Liu KW; Li Y; Lu X; Cheng T; Yiin JJ; Lu S; Keezer S; Fenton T; Furnari FB; Hamilton RL; Vuori K; Sarkaria JN; Nagane M; Nishikawa R; Cavenee WK; Cheng SY
    J Clin Invest; 2011 Dec; 121(12):4670-84. PubMed ID: 22080864
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion.
    Jarzynka MJ; Hu B; Hui KM; Bar-Joseph I; Gu W; Hirose T; Haney LB; Ravichandran KS; Nishikawa R; Cheng SY
    Cancer Res; 2007 Aug; 67(15):7203-11. PubMed ID: 17671188
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ZD6474, a multitargeted inhibitor for receptor tyrosine kinases, suppresses growth of gliomas expressing an epidermal growth factor receptor mutant, EGFRvIII, in the brain.
    Yiin JJ; Hu B; Schornack PA; Sengar RS; Liu KW; Feng H; Lieberman FS; Chiou SH; Sarkaria JN; Wiener EC; Ma HI; Cheng SY
    Mol Cancer Ther; 2010 Apr; 9(4):929-41. PubMed ID: 20371720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. EGFR Signals through a DOCK180-MLK3 Axis to Drive Glioblastoma Cell Invasion.
    Misek SA; Chen J; Schroeder L; Rattanasinchai C; Sample A; Sarkaria JN; Gallo KA
    Mol Cancer Res; 2017 Aug; 15(8):1085-1095. PubMed ID: 28487380
    [TBL] [Abstract][Full Text] [Related]  

  • 8. EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway.
    Bonavia R; Inda MM; Vandenberg S; Cheng SY; Nagane M; Hadwiger P; Tan P; Sah DW; Cavenee WK; Furnari FB
    Oncogene; 2012 Sep; 31(36):4054-66. PubMed ID: 22139077
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular characterization of EGFR and EGFRvIII signaling networks in human glioblastoma tumor xenografts.
    Johnson H; Del Rosario AM; Bryson BD; Schroeder MA; Sarkaria JN; White FM
    Mol Cell Proteomics; 2012 Dec; 11(12):1724-40. PubMed ID: 22964225
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prostaglandin E2 activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK.
    Bidwell P; Joh K; Leaver HA; Rizzo MT
    Prostaglandins Other Lipid Mediat; 2010 Feb; 91(1-2):18-29. PubMed ID: 20015475
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulatory role of guanine nucleotide exchange factor (GEF) Dock180 phosphorylation on Tyr/Ser in mediation of gastric mucosal Rac1 activation in response to Helicobacter pylori and ghrelin.
    Slomiany BL; Slomiany A
    Inflammopharmacology; 2015 Jun; 23(2-3):111-8. PubMed ID: 25957600
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme.
    Learn CA; Hartzell TL; Wikstrand CJ; Archer GE; Rich JN; Friedman AH; Friedman HS; Bigner DD; Sampson JH
    Clin Cancer Res; 2004 May; 10(9):3216-24. PubMed ID: 15131063
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nimotuzumab enhances temozolomide-induced growth suppression of glioma cells expressing mutant EGFR in vivo.
    Nitta Y; Shimizu S; Shishido-Hara Y; Suzuki K; Shiokawa Y; Nagane M
    Cancer Med; 2016 Mar; 5(3):486-99. PubMed ID: 26778701
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells.
    Hu J; Jo M; Cavenee WK; Furnari F; VandenBerg SR; Gonias SL
    Proc Natl Acad Sci U S A; 2011 Sep; 108(38):15984-9. PubMed ID: 21896743
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells.
    Vallés AM; Beuvin M; Boyer B
    J Biol Chem; 2004 Oct; 279(43):44490-6. PubMed ID: 15308668
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells.
    Fortin SP; Ennis MJ; Schumacher CA; Zylstra-Diegel CR; Williams BO; Ross JT; Winkles JA; Loftus JC; Symons MH; Tran NL
    Mol Cancer Res; 2012 Jul; 10(7):958-68. PubMed ID: 22571869
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The bipartite rac1 Guanine nucleotide exchange factor engulfment and cell motility 1/dedicator of cytokinesis 180 (elmo1/dock180) protects endothelial cells from apoptosis in blood vessel development.
    Schäker K; Bartsch S; Patry C; Stoll SJ; Hillebrands JL; Wieland T; Kroll J
    J Biol Chem; 2015 Mar; 290(10):6408-18. PubMed ID: 25586182
    [TBL] [Abstract][Full Text] [Related]  

  • 18. EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts.
    Lal B; Goodwin CR; Sang Y; Foss CA; Cornet K; Muzamil S; Pomper MG; Kim J; Laterra J
    Mol Cancer Ther; 2009 Jul; 8(7):1751-60. PubMed ID: 19584231
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of collapsin response mediator Protein1, as detected by iTRAQ analysis, promotes invasion of human gliomas expressing mutant EGFRvIII.
    Mukherjee J; DeSouza LV; Micallef J; Karim Z; Croul S; Siu KW; Guha A
    Cancer Res; 2009 Nov; 69(22):8545-54. PubMed ID: 19903856
    [TBL] [Abstract][Full Text] [Related]  

  • 20. COPI-Mediated Nuclear Translocation of EGFRvIII Promotes STAT3 Phosphorylation and PKM2 Nuclear Localization.
    Zhang M; Sun H; Deng Y; Su M; Wei S; Wang P; Yu L; Liu J; Guo J; Wang X; Han X; He Q; Shen L
    Int J Biol Sci; 2019; 15(1):114-126. PubMed ID: 30662352
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.