BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

95 related articles for article (PubMed ID: 23732628)

  • 1. Convenient microwave-assisted synthesis of lipophilic sulfenamide prodrugs of metformin.
    Huttunen KM; Leppänen J; Laine K; Vepsäläinen J; Rautio J
    Eur J Pharm Sci; 2013 Jul; 49(4):624-8. PubMed ID: 23732628
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro and in vivo evaluation of a sulfenamide prodrug of basic metformin.
    Huttunen KM; Leppänen J; Vepsäläinen J; Sirviö J; Laine K; Rautio J
    J Pharm Sci; 2012 Aug; 101(8):2854-60. PubMed ID: 22648910
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Preparation, characterization and in vivo conversion of new water-soluble sulfenamide prodrugs of carbamazepine.
    Hemenway JN; Nti-Addae K; Guarino VR; Stella VJ
    Bioorg Med Chem Lett; 2007 Dec; 17(23):6629-32. PubMed ID: 17928225
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The first bioreversible prodrug of metformin with improved lipophilicity and enhanced intestinal absorption.
    Huttunen KM; Mannila A; Laine K; Kemppainen E; Leppänen J; Vepsäläinen J; Järvinen T; Rautio J
    J Med Chem; 2009 Jul; 52(14):4142-8. PubMed ID: 19522462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MDCK cell permeability characteristics of a sulfenamide prodrug: strategic implications in considering sulfenamide prodrugs for oral delivery of NH-acids.
    Guarino VR; Nti-Addae K; Stella VJ
    Bioorg Med Chem Lett; 2011 Jan; 21(1):172-5. PubMed ID: 21126873
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sustained release of metformin via red blood cell accumulated sulfenamide prodrug.
    Peura L; Huttunen KM
    J Pharm Sci; 2014 Jul; 103(7):2207-2210. PubMed ID: 24891115
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Determination of the permeability characteristics of two sulfenamide prodrugs of linezolid across Caco-2 cells.
    Nti-Addae KW; Guarino VR; Dalwadi G; Stella VJ
    J Pharm Sci; 2012 Sep; 101(9):3134-41. PubMed ID: 22374830
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glutathione-S-transferase selective release of metformin from its sulfonamide prodrug.
    Rautio J; Vernerová M; Aufderhaar I; Huttunen KM
    Bioorg Med Chem Lett; 2014 Nov; 24(21):5034-6. PubMed ID: 25248681
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bifunctional peptidomimetic prodrugs of didanosine for improved intestinal permeability and enhanced acidic stability: synthesis, transepithelial transport, chemical stability and pharmacokinetics.
    Yan Z; Sun J; Chang Y; Liu Y; Fu Q; Xu Y; Sun Y; Pu X; Zhang Y; Jing Y; Yin S; Zhu M; Wang Y; He Z
    Mol Pharm; 2011 Apr; 8(2):319-29. PubMed ID: 21280612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metformin and Its Sulfenamide Prodrugs Inhibit Human Cholinesterase Activity.
    Markowicz-Piasecka M; Sikora J; Mateusiak Ł; Mikiciuk-Olasik E; Huttunen KM
    Oxid Med Cell Longev; 2017; 2017():7303096. PubMed ID: 28770024
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, transport and pharmacokinetics of 5'-amino acid ester prodrugs of 1-beta-D-arabinofuranosylcytosine.
    Sun Y; Sun J; Shi S; Jing Y; Yin S; Chen Y; Li G; Xu Y; He Z
    Mol Pharm; 2009; 6(1):315-25. PubMed ID: 19115956
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Determination of metformin and its prodrugs in human and rat blood by hydrophilic interaction liquid chromatography.
    Huttunen KM; Rautio J; Leppänen J; Vepsäläinen J; Keski-Rahkonen P
    J Pharm Biomed Anal; 2009 Oct; 50(3):469-74. PubMed ID: 19481899
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An amide-based sulfenamide prodrug of gamma secretase inhibitor BMS-708163 delivers parent drug from an oral conventional solid dosage form in male beagle dog.
    Guarino VR; Olson RE; Everlof JG; Wang N; McDonald I; Haskell R; Clarke W; Lentz KA
    Bioorg Med Chem Lett; 2020 Feb; 30(3):126856. PubMed ID: 31870650
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and assessment of first-generation polyamidoamine dendrimer prodrugs to enhance the cellular permeability of P-gp substrates.
    Najlah M; Freeman S; Attwood D; D'Emanuele A
    Bioconjug Chem; 2007; 18(3):937-46. PubMed ID: 17355118
    [TBL] [Abstract][Full Text] [Related]  

  • 15. O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of Trypanosoma brucei rhodesiense infection.
    Ansede JH; Anbazhagan M; Brun R; Easterbrook JD; Hall JE; Boykin DW
    J Med Chem; 2004 Aug; 47(17):4335-8. PubMed ID: 15294005
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro conversion of model sulfenamide prodrugs in the presence of small molecule thiols.
    Nti-Addae KW; Stella VJ
    J Pharm Sci; 2011 Mar; 100(3):1001-8. PubMed ID: 20957747
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Absorption of ester prodrugs in Caco-2 and rat intestine models.
    He X; Sugawara M; Takekuma Y; Miyazaki K
    Antimicrob Agents Chemother; 2004 Jul; 48(7):2604-9. PubMed ID: 15215116
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reprint of "MDCK cell permeability characteristics of a sulfenamide produg: strategic implications in considering sulfenamide prodrugs for oral delivery of NH acids" [Bioorg. Med. Chem. Lett. 21 (2011) 172-175].
    Guarino VR; Nti-Addae K; Stella VJ
    Bioorg Med Chem Lett; 2011 May; 21(9):2780-3. PubMed ID: 21513867
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, in vitro evaluation, and antileishmanial activity of water-soluble prodrugs of buparvaquone.
    Mäntylä A; Garnier T; Rautio J; Nevalainen T; Vepsälainen J; Koskinen A; Croft SL; Järvinen T
    J Med Chem; 2004 Jan; 47(1):188-95. PubMed ID: 14695832
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Propylene glycol-linked amino acid/dipeptide diester prodrugs of oleanolic acid for PepT1-mediated transport: synthesis, intestinal permeability, and pharmacokinetics.
    Cao F; Gao Y; Wang M; Fang L; Ping Q
    Mol Pharm; 2013 Apr; 10(4):1378-87. PubMed ID: 23339520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.