BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

467 related articles for article (PubMed ID: 23739956)

  • 1. MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration.
    Harms AS; Cao S; Rowse AL; Thome AD; Li X; Mangieri LR; Cron RQ; Shacka JJ; Raman C; Standaert DG
    J Neurosci; 2013 Jun; 33(23):9592-600. PubMed ID: 23739956
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Allelic difference in Mhc2ta confers altered microglial activation and susceptibility to α-synuclein-induced dopaminergic neurodegeneration.
    Jimenez-Ferrer I; Jewett M; Tontanahal A; Romero-Ramos M; Swanberg M
    Neurobiol Dis; 2017 Oct; 106():279-290. PubMed ID: 28736195
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.
    Qin H; Buckley JA; Li X; Liu Y; Fox TH; Meares GP; Yu H; Yan Z; Harms AS; Li Y; Standaert DG; Benveniste EN
    J Neurosci; 2016 May; 36(18):5144-59. PubMed ID: 27147665
    [TBL] [Abstract][Full Text] [Related]  

  • 4. T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson's disease.
    Subbarayan MS; Hudson C; Moss LD; Nash KR; Bickford PC
    J Neuroinflammation; 2020 Aug; 17(1):242. PubMed ID: 32799878
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease.
    Williams GP; Schonhoff AM; Jurkuvenaite A; Thome AD; Standaert DG; Harms AS
    J Neuroinflammation; 2018 Aug; 15(1):244. PubMed ID: 30165873
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ciita Regulates Local and Systemic Immune Responses in a Combined rAAV-α-synuclein and Preformed Fibril-Induced Rat Model for Parkinson's Disease.
    Fredlund F; Jimenez-Ferrer I; Grabert K; Belfiori LF; Luk K; Swanberg M
    J Parkinsons Dis; 2024; 14(4):693-711. PubMed ID: 38728204
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease.
    Harms AS; Thome AD; Yan Z; Schonhoff AM; Williams GP; Li X; Liu Y; Qin H; Benveniste EN; Standaert DG
    Exp Neurol; 2018 Feb; 300():179-187. PubMed ID: 29155051
    [TBL] [Abstract][Full Text] [Related]  

  • 8. microRNA-155 Regulates Alpha-Synuclein-Induced Inflammatory Responses in Models of Parkinson Disease.
    Thome AD; Harms AS; Volpicelli-Daley LA; Standaert DG
    J Neurosci; 2016 Feb; 36(8):2383-90. PubMed ID: 26911687
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson's disease.
    George S; Rey NL; Tyson T; Esquibel C; Meyerdirk L; Schulz E; Pierce S; Burmeister AR; Madaj Z; Steiner JA; Escobar Galvis ML; Brundin L; Brundin P
    Mol Neurodegener; 2019 Aug; 14(1):34. PubMed ID: 31419995
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modeling Parkinson's disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain.
    Thakur P; Breger LS; Lundblad M; Wan OW; Mattsson B; Luk KC; Lee VMY; Trojanowski JQ; Björklund A
    Proc Natl Acad Sci U S A; 2017 Sep; 114(39):E8284-E8293. PubMed ID: 28900002
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeted overexpression of human alpha-synuclein triggers microglial activation and an adaptive immune response in a mouse model of Parkinson disease.
    Theodore S; Cao S; McLean PJ; Standaert DG
    J Neuropathol Exp Neurol; 2008 Dec; 67(12):1149-58. PubMed ID: 19018246
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.
    Gordon R; Singh N; Lawana V; Ghosh A; Harischandra DS; Jin H; Hogan C; Sarkar S; Rokad D; Panicker N; Anantharam V; Kanthasamy AG; Kanthasamy A
    Neurobiol Dis; 2016 Sep; 93():96-114. PubMed ID: 27151770
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Minimally Toxic Dose of Lipopolysaccharide and α-Synuclein Oligomer Elicit Synergistic Dopaminergic Neurodegeneration: Role and Mechanism of Microglial NOX2 Activation.
    Zhang W; Gao JH; Yan ZF; Huang XY; Guo P; Sun L; Liu Z; Hu Y; Zuo LJ; Yu SY; Cao CJ; Wang XM; Hong JS
    Mol Neurobiol; 2018 Jan; 55(1):619-632. PubMed ID: 27975175
    [TBL] [Abstract][Full Text] [Related]  

  • 14. α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration.
    Harms AS; Delic V; Thome AD; Bryant N; Liu Z; Chandra S; Jurkuvenaite A; West AB
    Acta Neuropathol Commun; 2017 Nov; 5(1):85. PubMed ID: 29162163
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease.
    Thome AD; Standaert DG; Harms AS
    PLoS One; 2015; 10(10):e0140566. PubMed ID: 26469270
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson's disease.
    Williams GP; Schonhoff AM; Jurkuvenaite A; Gallups NJ; Standaert DG; Harms AS
    Brain; 2021 Aug; 144(7):2047-2059. PubMed ID: 33704423
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Astragaloside IV Inhibits Rotenone-Induced α-syn Presentation and the CD4 T-Cell Immune Response.
    Wang M; Sun F; Han X; Wang N; Liu Y; Cai J; Tong S; Wang R; Wang H
    Mol Neurobiol; 2024 Jan; 61(1):252-265. PubMed ID: 37603153
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dopamine receptor D3 expressed on CD4+ T cells favors neurodegeneration of dopaminergic neurons during Parkinson's disease.
    González H; Contreras F; Prado C; Elgueta D; Franz D; Bernales S; Pacheco R
    J Immunol; 2013 May; 190(10):5048-56. PubMed ID: 23589621
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cx3cr1-deficiency exacerbates alpha-synuclein-A53T induced neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease.
    Castro-Sánchez S; García-Yagüe ÁJ; López-Royo T; Casarejos M; Lanciego JL; Lastres-Becker I
    Glia; 2018 Aug; 66(8):1752-1762. PubMed ID: 29624735
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Parkinson's disease-related protein DJ-1 protects dopaminergic neurons in vivo and cultured cells from alpha-synuclein and 6-hydroxydopamine toxicity.
    Batelli S; Invernizzi RW; Negro A; Calcagno E; Rodilossi S; Forloni G; Albani D
    Neurodegener Dis; 2015; 15(1):13-23. PubMed ID: 25500798
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.