269 related articles for article (PubMed ID: 23744512)
1. In vivo evidence for a prodrug activation mechanism during colibactin maturation.
Bian X; Fu J; Plaza A; Herrmann J; Pistorius D; Stewart AF; Zhang Y; Müller R
Chembiochem; 2013 Jul; 14(10):1194-7. PubMed ID: 23744512
[TBL] [Abstract][Full Text] [Related]
2. A prodrug resistance mechanism is involved in colibactin biosynthesis and cytotoxicity.
Brotherton CA; Balskus EP
J Am Chem Soc; 2013 Mar; 135(9):3359-62. PubMed ID: 23406518
[TBL] [Abstract][Full Text] [Related]
3. Critical Intermediates Reveal New Biosynthetic Events in the Enigmatic Colibactin Pathway.
Li ZR; Li Y; Lai JY; Tang J; Wang B; Lu L; Zhu G; Wu X; Xu Y; Qian PY
Chembiochem; 2015 Aug; 16(12):1715-9. PubMed ID: 26052818
[TBL] [Abstract][Full Text] [Related]
4. Isolation of a metabolite from the pks island provides insights into colibactin biosynthesis and activity.
Brotherton CA; Wilson M; Byrd G; Balskus EP
Org Lett; 2015 Mar; 17(6):1545-8. PubMed ID: 25753745
[TBL] [Abstract][Full Text] [Related]
5. Colibactin biosynthesis and biological activity depend on the rare aminomalonyl polyketide precursor.
Brachmann AO; Garcie C; Wu V; Martin P; Ueoka R; Oswald E; Piel J
Chem Commun (Camb); 2015 Aug; 51(66):13138-41. PubMed ID: 26191546
[TBL] [Abstract][Full Text] [Related]
6. ClbM is a versatile, cation-promiscuous MATE transporter found in the colibactin biosynthetic gene cluster.
Mousa JJ; Newsome RC; Yang Y; Jobin C; Bruner SD
Biochem Biophys Res Commun; 2017 Jan; 482(4):1233-1239. PubMed ID: 27939886
[TBL] [Abstract][Full Text] [Related]
7. Structure elucidation of colibactin and its DNA cross-links.
Xue M; Kim CS; Healy AR; Wernke KM; Wang Z; Frischling MC; Shine EE; Wang W; Herzon SB; Crawford JM
Science; 2019 Sep; 365(6457):. PubMed ID: 31395743
[TBL] [Abstract][Full Text] [Related]
8. Activity-Based Probe for Screening of High-Colibactin Producers from Clinical Samples.
Hirayama Y; Tsunematsu Y; Yoshikawa Y; Tamafune R; Matsuzaki N; Iwashita Y; Ohnishi I; Tanioka F; Sato M; Miyoshi N; Mutoh M; Ishikawa H; Sugimura H; Wakabayashi K; Watanabe K
Org Lett; 2019 Jun; 21(12):4490-4494. PubMed ID: 31192617
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and reactivity of precolibactin 886.
Healy AR; Wernke KM; Kim CS; Lees NR; Crawford JM; Herzon SB
Nat Chem; 2019 Oct; 11(10):890-898. PubMed ID: 31548676
[TBL] [Abstract][Full Text] [Related]
10. MATE transport of the E. coli-derived genotoxin colibactin.
Mousa JJ; Yang Y; Tomkovich S; Shima A; Newsome RC; Tripathi P; Oswald E; Bruner SD; Jobin C
Nat Microbiol; 2016 Jan; 1():15009. PubMed ID: 27571755
[TBL] [Abstract][Full Text] [Related]
11. ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia coli.
Wallenstein A; Rehm N; Brinkmann M; Selle M; Bossuet-Greif N; Sauer D; Bunk B; Spröer C; Wami HT; Homburg S; von Bünau R; König S; Nougayrède JP; Overmann J; Oswald E; Müller R; Dobrindt U
mSphere; 2020 Jul; 5(4):. PubMed ID: 32669458
[TBL] [Abstract][Full Text] [Related]
12. Characterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin.
Zha L; Wilson MR; Brotherton CA; Balskus EP
ACS Chem Biol; 2016 May; 11(5):1287-95. PubMed ID: 26890481
[TBL] [Abstract][Full Text] [Related]
13. Evolution of Polymyxin Resistance Regulates Colibactin Production in
Sadecki PW; Balboa SJ; Lopez LR; Kedziora KM; Arthur JC; Hicks LM
ACS Chem Biol; 2021 Jul; 16(7):1243-1254. PubMed ID: 34232632
[TBL] [Abstract][Full Text] [Related]
14. Escherichia coli ClbS is a colibactin resistance protein.
Bossuet-Greif N; Dubois D; Petit C; Tronnet S; Martin P; Bonnet R; Oswald E; Nougayrède JP
Mol Microbiol; 2016 Mar; 99(5):897-908. PubMed ID: 26560421
[TBL] [Abstract][Full Text] [Related]
15. ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance.
Tripathi P; Shine EE; Healy AR; Kim CS; Herzon SB; Bruner SD; Crawford JM
J Am Chem Soc; 2017 Dec; 139(49):17719-17722. PubMed ID: 29112397
[TBL] [Abstract][Full Text] [Related]
16. Robust performance of a live bacterial therapeutic chassis lacking the colibactin gene cluster.
Kalantari A; James MJ; Renaud LA; Perreault M; Monahan CE; McDonald MN; Hava DL; Isabella VM
PLoS One; 2023; 18(2):e0280499. PubMed ID: 36730255
[TBL] [Abstract][Full Text] [Related]
17. Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin.
Li ZR; Li J; Gu JP; Lai JY; Duggan BM; Zhang WP; Li ZL; Li YX; Tong RB; Xu Y; Lin DH; Moore BS; Qian PY
Nat Chem Biol; 2016 Oct; 12(10):773-5. PubMed ID: 27547923
[TBL] [Abstract][Full Text] [Related]
18. A Mechanistic Model for Colibactin-Induced Genotoxicity.
Healy AR; Nikolayevskiy H; Patel JR; Crawford JM; Herzon SB
J Am Chem Soc; 2016 Dec; 138(48):15563-15570. PubMed ID: 27934011
[TBL] [Abstract][Full Text] [Related]
19. Gut symbionts from distinct hosts exhibit genotoxic activity via divergent colibactin biosynthesis pathways.
Engel P; Vizcaino MI; Crawford JM
Appl Environ Microbiol; 2015 Feb; 81(4):1502-12. PubMed ID: 25527542
[TBL] [Abstract][Full Text] [Related]
20. The human gut bacterial genotoxin colibactin alkylates DNA.
Wilson MR; Jiang Y; Villalta PW; Stornetta A; Boudreau PD; Carrá A; Brennan CA; Chun E; Ngo L; Samson LD; Engelward BP; Garrett WS; Balbo S; Balskus EP
Science; 2019 Feb; 363(6428):. PubMed ID: 30765538
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]