These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

74 related articles for article (PubMed ID: 23747226)

  • 1. Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: observation of extensive dynamics in an enzyme/inhibitor complex.
    Kim SH; Constantine KL; Duke GJ; Goldfarb V; Hunt JT; Johnson S; Kish K; Klei HE; McDonnell PA; Metzler WJ; Mueller L; Poss MA; Fairchild CR; Bhide RS
    Bioorg Med Chem Lett; 2013 Jul; 23(14):4107-11. PubMed ID: 23747226
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An EPSP synthase inhibitor joining shikimate 3-phosphate with glyphosate: synthesis and ligand binding studies.
    Marzabadi MR; Gruys KJ; Pansegrau PD; Walker MC; Yuen HK; Sikorski JA
    Biochemistry; 1996 Apr; 35(13):4199-210. PubMed ID: 8672456
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of hydrolysis-resistant pyridoxal 5'-phosphate analogs and their biochemical and X-ray crystallographic characterization with the pyridoxal phosphatase chronophin.
    Knobloch G; Jabari N; Stadlbauer S; Schindelin H; Köhn M; Gohla A
    Bioorg Med Chem; 2015 Jun; 23(12):2819-27. PubMed ID: 25783190
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, structural characterization by IR, (1) H, (13) C, (15) N, 2D-NMR, X-ray diffraction and evaluation of a new class of phenylaminoacetic acid benzylidene hydrazines as pfENR inhibitors.
    Samal RP; Khedkar VM; Pissurlenkar RR; Bwalya AG; Tasdemir D; Joshi RA; Rajamohanan PR; Puranik VG; Coutinho EC
    Chem Biol Drug Des; 2013 Jun; 81(6):715-29. PubMed ID: 23398677
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Virtual Screening with Docking Simulations and Biochemical Evaluation of VHY Phosphatase Inhibitors.
    Park H; Lee HS; Kim SJ
    Chem Pharm Bull (Tokyo); 2015; 63(10):807-11. PubMed ID: 26423037
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of non-hydrolyzable homoisoprenoid α-monofluorophosphonate inhibitors of PPAPDC family integral membrane lipid phosphatases.
    Subramanian T; Ren H; Subramanian KL; Sunkara M; Onono FO; Morris AJ; Spielmann HP
    Bioorg Med Chem Lett; 2014 Sep; 24(18):4414-4417. PubMed ID: 25150376
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small molecule interactions with protein-tyrosine phosphatase PTP1B and their use in inhibitor design.
    Burke TR; Ye B; Yan X; Wang S; Jia Z; Chen L; Zhang ZY; Barford D
    Biochemistry; 1996 Dec; 35(50):15989-96. PubMed ID: 8973169
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities: a novel target of lithium therapy.
    Patel S; Yenush L; Rodríguez PL; Serrano R; Blundell TL
    J Mol Biol; 2002 Jan; 315(4):677-85. PubMed ID: 11812139
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Towards the development of novel antibiotics: synthesis and evaluation of a mechanism-based inhibitor of Kdo8P synthase.
    Du S; Faiger H; Belakhov V; Baasov T
    Bioorg Med Chem; 1999 Dec; 7(12):2671-82. PubMed ID: 10658571
    [TBL] [Abstract][Full Text] [Related]  

  • 10. How calcium inhibits the magnesium-dependent enzyme human phosphoserine phosphatase.
    Peeraer Y; Rabijns A; Collet JF; Van Schaftingen E; De Ranter C
    Eur J Biochem; 2004 Aug; 271(16):3421-7. PubMed ID: 15291819
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor.
    Luić M; Koellner G; Yokomatsu T; Shibuya S; Bzowska A
    Acta Crystallogr D Biol Crystallogr; 2004 Aug; 60(Pt 8):1417-24. PubMed ID: 15272165
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Monoaryl- and bisaryldihydroxytropolones as potent inhibitors of inositol monophosphatase.
    Piettre SR; André C; Chanal MC; Ducep JB; Lesur B; Piriou F; Raboisson P; Rondeau JM; Schelcher C; Zimmermann P; Ganzhorn AJ
    J Med Chem; 1997 Dec; 40(26):4208-21. PubMed ID: 9435892
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Removal of the phosphate group in mechanism-based inhibitors of inositol monophosphatase leads to unusual inhibitory activity.
    Miller DJ; Bashir-Uddin Surfraz M; Akhtar M; Gani D; Allemann RK
    Org Biomol Chem; 2004 Mar; 2(5):671-88. PubMed ID: 14985807
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Isoprenoid biosynthesis via the methylerythritol phosphate pathway: structural variations around phosphonate anchor and spacer of fosmidomycin, a potent inhibitor of deoxyxylulose phosphate reductoisomerase.
    Zinglé C; Kuntz L; Tritsch D; Grosdemange-Billiard C; Rohmer M
    J Org Chem; 2010 May; 75(10):3203-7. PubMed ID: 20429517
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biochemical characterization and ligand-binding properties of trehalose-6-phosphate phosphatase from Mycobacterium tuberculosis.
    Shi L; Zhang H; Qiu Y; Wang Q; Wu X; Wang H; Zhang X; Lin D
    Acta Biochim Biophys Sin (Shanghai); 2013 Oct; 45(10):837-44. PubMed ID: 23903290
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and stereochemistry of the terminal spiroketal domain of the phosphatase inhibitor dinophysistoxin-2.
    Forsyth CJ; Wang C
    Bioorg Med Chem Lett; 2008 May; 18(10):3043-6. PubMed ID: 18226903
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Competitive inhibitors of yeast phosphoglucose isomerase: synthesis and evaluation of new types of phosphorylated sugars from the synthon D-arabinolactone-5-phosphate.
    Hardré R; Salmon L
    Carbohydr Res; 1999 May; 318(1-4):110-5. PubMed ID: 10576923
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural Analysis of Binding Determinants of
    Harvey CM; O'Toole KH; Liu C; Mariano P; Dunaway-Mariano D; Allen KN
    Biochemistry; 2020 Sep; 59(35):3247-3257. PubMed ID: 32786412
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme.
    Barbosa JA; Smith BJ; DeGori R; Ooi HC; Marcuccio SM; Campi EM; Jackson WR; Brossmer R; Sommer M; Lawrence MC
    J Mol Biol; 2000 Oct; 303(3):405-21. PubMed ID: 11031117
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Binding of 5-phospho-D-arabinonohydroxamate and 5-phospho-D-arabinonate inhibitors to zinc phosphomannose isomerase from Candida albicans studied by polarizable molecular mechanics and quantum mechanics.
    Roux C; Gresh N; Perera LE; Piquemal JP; Salmon L
    J Comput Chem; 2007 Apr; 28(5):938-57. PubMed ID: 17253648
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.