BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 23747250)

  • 1. The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.
    Ezzat S; Zheng L; Florez JC; Stefan N; Mayr T; Hliang MM; Jablonski K; Harden M; Stančáková A; Laakso M; Haring HU; Ullrich A; Asa SL
    Cell Metab; 2013 Jun; 17(6):929-940. PubMed ID: 23747250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Does a single nucleotide polymorphism in the FGFR explain the connection between diabetes and cancer?
    Gallagher EJ; LeRoith D
    Cell Metab; 2013 Jun; 17(6):808-809. PubMed ID: 23747238
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The FGFR4-G388R polymorphism promotes mitochondrial STAT3 serine phosphorylation to facilitate pituitary growth hormone cell tumorigenesis.
    Tateno T; Asa SL; Zheng L; Mayr T; Ullrich A; Ezzat S
    PLoS Genet; 2011 Dec; 7(12):e1002400. PubMed ID: 22174695
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site.
    Ulaganathan VK; Sperl B; Rapp UR; Ullrich A
    Nature; 2015 Dec; 528(7583):570-4. PubMed ID: 26675719
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FGFR4 polymorphic variants modulate phenotypic features of Cushing disease.
    Nakano-Tateno T; Tateno T; Hlaing MM; Zheng L; Yoshimoto K; Yamada S; Asa SL; Ezzat S
    Mol Endocrinol; 2014 Apr; 28(4):525-33. PubMed ID: 24625004
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation.
    Sugiyama N; Varjosalo M; Meller P; Lohi J; Hyytiäinen M; Kilpinen S; Kallioniemi O; Ingvarsen S; Engelholm LH; Taipale J; Alitalo K; Keski-Oja J; Lehti K
    Cancer Res; 2010 Oct; 70(20):7851-61. PubMed ID: 20876804
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The FGFR4-G388R single-nucleotide polymorphism alters pancreatic neuroendocrine tumor progression and response to mTOR inhibition therapy.
    Serra S; Zheng L; Hassan M; Phan AT; Woodhouse LJ; Yao JC; Ezzat S; Asa SL
    Cancer Res; 2012 Nov; 72(22):5683-91. PubMed ID: 22986737
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FGFR4 polymorphic alleles modulate mitochondrial respiration: A novel target for somatostatin analog action in pituitary tumors.
    Ezzat S; Wang R; Pintilie M; Asa SL
    Oncotarget; 2017 Jan; 8(2):3481-3494. PubMed ID: 27966451
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of heterozygosity and DNA methylation affect germline fibroblast growth factor receptor 4 polymorphism to direct allelic selection in breast cancer.
    Zhu X; Zheng L; Asa SL; Ezzat S
    Am J Pathol; 2010 Dec; 177(6):2860-9. PubMed ID: 21037081
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival.
    Tiong KH; Tan BS; Choo HL; Chung FF; Hii LW; Tan SH; Khor NT; Wong SF; See SJ; Tan YF; Rosli R; Cheong SK; Leong CO
    Oncotarget; 2016 Sep; 7(36):57633-57650. PubMed ID: 27192118
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function.
    Lin HM; Lee JH; Yadav H; Kamaraju AK; Liu E; Zhigang D; Vieira A; Kim SJ; Collins H; Matschinsky F; Harlan DM; Roberts AB; Rane SG
    J Biol Chem; 2009 May; 284(18):12246-57. PubMed ID: 19265200
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet.
    Lutz SZ; Hennige AM; Peter A; Kovarova M; Totsikas C; Machann J; Kröber SM; Sperl B; Schleicher E; Schick F; Heni M; Ullrich A; Häring HU; Stefan N
    J Clin Endocrinol Metab; 2019 Jun; 104(6):2041-2053. PubMed ID: 30541128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fibroblast Growth Factor 19-Mediated Up-regulation of SYR-Related High-Mobility Group Box 18 Promotes Hepatocellular Carcinoma Metastasis by Transactivating Fibroblast Growth Factor Receptor 4 and Fms-Related Tyrosine Kinase 4.
    Chen J; Du F; Dang Y; Li X; Qian M; Feng W; Qiao C; Fan D; Nie Y; Wu K; Xia L
    Hepatology; 2020 May; 71(5):1712-1731. PubMed ID: 31529503
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FGFR4 Gly388Arg polymorphism may affect the clinical stage of patients with lung cancer by modulating the transcriptional profile of normal lung.
    Falvella FS; Frullanti E; Galvan A; Spinola M; Noci S; De Cecco L; Nosotti M; Santambrogio L; Incarbone M; Alloisio M; Calabrò E; Pastorino U; Skaug V; Haugen A; Taioli E; Dragani TA
    Int J Cancer; 2009 Jun; 124(12):2880-5. PubMed ID: 19296538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fibroblast growth factor 19 is correlated with an unfavorable prognosis and promotes progression by activating fibroblast growth factor receptor 4 in advanced-stage serous ovarian cancer.
    Hu L; Cong L
    Oncol Rep; 2015 Nov; 34(5):2683-91. PubMed ID: 26323668
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice.
    Wu X; Ge H; Lemon B; Weiszmann J; Gupte J; Hawkins N; Li X; Tang J; Lindberg R; Li Y
    Proc Natl Acad Sci U S A; 2009 Aug; 106(34):14379-84. PubMed ID: 19706524
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy.
    Grabner A; Amaral AP; Schramm K; Singh S; Sloan A; Yanucil C; Li J; Shehadeh LA; Hare JM; David V; Martin A; Fornoni A; Di Marco GS; Kentrup D; Reuter S; Mayer AB; Pavenstädt H; Stypmann J; Kuhn C; Hille S; Frey N; Leifheit-Nestler M; Richter B; Haffner D; Abraham R; Bange J; Sperl B; Ullrich A; Brand M; Wolf M; Faul C
    Cell Metab; 2015 Dec; 22(6):1020-32. PubMed ID: 26437603
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7.
    Bai YP; Shang K; Chen H; Ding F; Wang Z; Liang C; Xu Y; Sun MH; Li YY
    Cancer Sci; 2015 Oct; 106(10):1278-87. PubMed ID: 26183471
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FGFR4 GLY388 isotype suppresses motility of MDA-MB-231 breast cancer cells by EDG-2 gene repression.
    Stadler CR; Knyazev P; Bange J; Ullrich A
    Cell Signal; 2006 Jun; 18(6):783-94. PubMed ID: 16109476
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex.
    Sugiyama N; Varjosalo M; Meller P; Lohi J; Chan KM; Zhou Z; Alitalo K; Taipale J; Keski-Oja J; Lehti K
    Proc Natl Acad Sci U S A; 2010 Sep; 107(36):15786-91. PubMed ID: 20798051
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.