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3. The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes. Rhodes B; Fürnrohr BG; Roberts AL; Tzircotis G; Schett G; Spector TD; Vyse TJ Ann Rheum Dis; 2012 Dec; 71(12):2028-34. PubMed ID: 22586164 [TBL] [Abstract][Full Text] [Related]
4. A systemic lupus erythematosus-associated R77H substitution in the CD11b chain of the Mac-1 integrin compromises leukocyte adhesion and phagocytosis. MacPherson M; Lek HS; Prescott A; Fagerholm SC J Biol Chem; 2011 May; 286(19):17303-10. PubMed ID: 21454473 [TBL] [Abstract][Full Text] [Related]
5. Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases. Roberts AL; Thomas ER; Bhosle S; Game L; Obraztsova O; Aitman TJ; Vyse TJ; Rhodes B Arthritis Res Ther; 2014 May; 16(3):R114. PubMed ID: 24886912 [TBL] [Abstract][Full Text] [Related]
6. ITGAM rs1143679 Variant in Systemic Lupus Erythematosus Is Associated with Increased Serum Calcification Propensity. Halfon M; Zhang L; Ehirchiou D; Pandian VD; Dahdal S; Huynh-Do U; Pasch A; Ribi C; Busso N Genes (Basel); 2023 May; 14(5):. PubMed ID: 37239465 [TBL] [Abstract][Full Text] [Related]
7. Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE). Han S; Kim-Howard X; Deshmukh H; Kamatani Y; Viswanathan P; Guthridge JM; Thomas K; Kaufman KM; Ojwang J; Rojas-Villarraga A; Baca V; Orozco L; Rhodes B; Choi CB; Gregersen PK; Merrill JT; James JA; Gaffney PM; Moser KL; Jacob CO; Kimberly RP; Harley JB; Bae SC; Anaya JM; Alarcón-Riquelme ME; Matsuda K; Vyse TJ; Nath SK Hum Mol Genet; 2009 Mar; 18(6):1171-80. PubMed ID: 19129174 [TBL] [Abstract][Full Text] [Related]
8. Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM. Maiti AK; Kim-Howard X; Motghare P; Pradhan V; Chua KH; Sun C; Arango-Guerrero MT; Ghosh K; Niewold TB; Harley JB; Anaya JM; Looger LL; Nath SK Hum Mol Genet; 2014 Aug; 23(15):4161-76. PubMed ID: 24608226 [TBL] [Abstract][Full Text] [Related]
9. Association between the functional ITGAM rs1143679 G/A polymorphism and systemic lupus erythematosus/lupus nephritis or rheumatoid arthritis: an update meta-analysis. Lee YH; Bae SC Rheumatol Int; 2015 May; 35(5):815-23. PubMed ID: 25315704 [TBL] [Abstract][Full Text] [Related]
10. A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus. Nath SK; Han S; Kim-Howard X; Kelly JA; Viswanathan P; Gilkeson GS; Chen W; Zhu C; McEver RP; Kimberly RP; Alarcón-Riquelme ME; Vyse TJ; Li QZ; Wakeland EK; Merrill JT; James JA; Kaufman KM; Guthridge JM; Harley JB Nat Genet; 2008 Feb; 40(2):152-4. PubMed ID: 18204448 [TBL] [Abstract][Full Text] [Related]
11. Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells. Fossati-Jimack L; Ling GS; Cortini A; Szajna M; Malik TH; McDonald JU; Pickering MC; Cook HT; Taylor PR; Botto M PLoS One; 2013; 8(2):e57082. PubMed ID: 23451151 [TBL] [Abstract][Full Text] [Related]
12. Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus. Järvinen TM; Hellquist A; Koskenmies S; Einarsdottir E; Panelius J; Hasan T; Julkunen H; Padyukov L; Kvarnström M; Wahren-Herlenius M; Nyberg F; D'Amato M; Kere J; Saarialho-Kere U PLoS One; 2010 Dec; 5(12):e14212. PubMed ID: 21151989 [TBL] [Abstract][Full Text] [Related]
13. The variant of CD11b, rs1143679 within ITGAM, is associated with systemic lupus erythematosus and clinical manifestations in Brazilian patients. Toller-Kawahisa JE; Vigato-Ferreira IC; Pancoto JA; Mendes-Junior CT; Martinez EZ; Palomino GM; Louzada-Júnior P; Donadi EA; Del Lama JE; Marzocchi-Machado CM Hum Immunol; 2014 Feb; 75(2):119-23. PubMed ID: 24269694 [TBL] [Abstract][Full Text] [Related]
14. ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico. Ramírez-Bello J; Sun C; Valencia-Pacheco G; Singh B; Barbosa-Cobos RE; Saavedra MA; López-Villanueva RF; Nath SK PLoS One; 2019; 14(11):e0224543. PubMed ID: 31774828 [TBL] [Abstract][Full Text] [Related]
15. ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry. Kim-Howard X; Maiti AK; Anaya JM; Bruner GR; Brown E; Merrill JT; Edberg JC; Petri MA; Reveille JD; Ramsey-Goldman R; Alarcon GS; Vyse TJ; Gilkeson G; Kimberly RP; James JA; Guthridge JM; Harley JB; Nath SK Ann Rheum Dis; 2010 Jul; 69(7):1329-32. PubMed ID: 19939855 [TBL] [Abstract][Full Text] [Related]
16. Mice expressing the variant rs1143679 allele of ITGAM (CD11b) show impaired DC-mediated T cell proliferation. Avery JT; Jimenez RV; Blake JL; Wright TT; Leόn-Ruiz B; Schoeb TR; Szalai AJ; Bullard DC Mamm Genome; 2019 Oct; 30(9-10):245-259. PubMed ID: 31673770 [TBL] [Abstract][Full Text] [Related]
17. Gene-function studies in systemic lupus erythematosus. Rosetti F; de la Cruz A; Crispín JC Curr Opin Rheumatol; 2019 Mar; 31(2):185-192. PubMed ID: 30672908 [TBL] [Abstract][Full Text] [Related]
18. Association between complement gene polymorphisms and systemic lupus erythematosus: a systematic review and meta-analysis. Ebrahimiyan H; Mostafaei S; Aslani S; Faezi ST; Farhadi E; Jamshidi A; Mahmoudi M Clin Exp Med; 2022 Aug; 22(3):427-438. PubMed ID: 34519938 [TBL] [Abstract][Full Text] [Related]
19. The many faces of Mac-1 in autoimmune disease. Rosetti F; Mayadas TN Immunol Rev; 2016 Jan; 269(1):175-93. PubMed ID: 26683153 [TBL] [Abstract][Full Text] [Related]
20. The Systemic Lupus Erythematosus-Associated Single Nucleotide Polymorphism rs1143678 in Integrin αM Cytoplasmic Tail Generates a 14-3-3ζ Binding Site That Is Proinflammatory. Ong LT; Tan HF; Feng C; Qu J; Loh SC; Bhattacharyya S; Tan SM J Immunol; 2017 Jan; 198(2):883-894. PubMed ID: 27974454 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]