BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 23754471)

  • 1. Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine.
    Cross PJ; Pietersma AL; Allison TM; Wilson-Coutts SM; Cochrane FC; Parker EJ
    Protein Sci; 2013 Aug; 22(8):1087-99. PubMed ID: 23754471
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery.
    Jiao W; Hutton RD; Cross PJ; Jameson GB; Parker EJ
    J Mol Biol; 2012 Jan; 415(4):716-26. PubMed ID: 22154807
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allosteric inhibitor specificity of Thermotoga maritima 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
    Cross PJ; Parker EJ
    FEBS Lett; 2013 Sep; 587(18):3063-8. PubMed ID: 23916814
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase - The importance of accommodating the active site water.
    Heyes LC; Reichau S; Cross PJ; Jameson GB; Parker EJ
    Bioorg Chem; 2014 Dec; 57():242-250. PubMed ID: 25245459
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis.
    Webby CJ; Jiao W; Hutton RD; Blackmore NJ; Baker HM; Baker EN; Jameson GB; Parker EJ
    J Biol Chem; 2010 Oct; 285(40):30567-76. PubMed ID: 20667835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis.
    Blackmore NJ; Reichau S; Jiao W; Hutton RD; Baker EN; Jameson GB; Parker EJ
    J Mol Biol; 2013 May; 425(9):1582-92. PubMed ID: 23274137
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reciprocal allostery arising from a bienzyme assembly controls aromatic amino acid biosynthesis in Prevotella nigrescens.
    Bai Y; Parker EJ
    J Biol Chem; 2021 Sep; 297(3):101038. PubMed ID: 34343567
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Pseudoisostructural Type II DAH7PS Enzyme from Pseudomonas aeruginosa: Alternative Evolutionary Strategies to Control Shikimate Pathway Flux.
    Sterritt OW; Kessans SA; Jameson GB; Parker EJ
    Biochemistry; 2018 May; 57(18):2667-2678. PubMed ID: 29608284
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli.
    Cui D; Deng A; Bai H; Yang Z; Liang Y; Liu Z; Qiu Q; Wang L; Liu S; Zhang Y; Shi Y; Qi J; Wen T
    J Struct Biol; 2019 Jun; 206(3):322-334. PubMed ID: 30946901
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Complex Formation between Two Biosynthetic Enzymes Modifies the Allosteric Regulatory Properties of Both: AN EXAMPLE OF MOLECULAR SYMBIOSIS.
    Blackmore NJ; Nazmi AR; Hutton RD; Webby MN; Baker EN; Jameson GB; Parker EJ
    J Biol Chem; 2015 Jul; 290(29):18187-18198. PubMed ID: 26032422
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interdomain Conformational Changes Provide Allosteric Regulation en Route to Chorismate.
    Nazmi AR; Lang EJM; Bai Y; Allison TM; Othman MH; Panjikar S; Arcus VL; Parker EJ
    J Biol Chem; 2016 Oct; 291(42):21836-21847. PubMed ID: 27502275
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis.
    Cross PJ; Dobson RC; Patchett ML; Parker EJ
    J Biol Chem; 2011 Mar; 286(12):10216-24. PubMed ID: 21282100
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using ᴅ-Amino Acids.
    Reichau S; Blackmore NJ; Jiao W; Parker EJ
    PLoS One; 2016; 11(4):e0152723. PubMed ID: 27128682
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Domain cross-talk within a bifunctional enzyme provides catalytic and allosteric functionality in the biosynthesis of aromatic amino acids.
    Bai Y; Lang EJM; Nazmi AR; Parker EJ
    J Biol Chem; 2019 Mar; 294(13):4828-4842. PubMed ID: 30670586
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure of phenylalanine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Escherichia coli.
    Shumilin IA; Kretsinger RH; Bauerle RH
    Structure; 1999 Jul; 7(7):865-75. PubMed ID: 10425687
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The diversity of allosteric controls at the gateway to aromatic amino acid biosynthesis.
    Light SH; Anderson WF
    Protein Sci; 2013 Apr; 22(4):395-404. PubMed ID: 23400945
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and functional characterisation of the entry point to pyocyanin biosynthesis in
    Sterritt OW; Lang EJM; Kessans SA; Ryan TM; Demeler B; Jameson GB; Parker EJ
    Biosci Rep; 2018 Oct; 38(5):. PubMed ID: 30242059
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Elevated tyrosine results in the cytosolic retention of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in Arabidopsis thaliana.
    Kanaris M; Poulin J; Shahinas D; Johnson D; Crowley VM; Fucile G; Provart N; Christendat D
    Plant J; 2022 Feb; 109(4):789-803. PubMed ID: 34797933
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Functional Unit of Neisseria meningitidis 3-Deoxy-ᴅ-Arabino-Heptulosonate 7-Phosphate Synthase Is Dimeric.
    Cross PJ; Heyes LC; Zhang S; Nazmi AR; Parker EJ
    PLoS One; 2016; 11(2):e0145187. PubMed ID: 26828675
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity.
    Nazmi AR; Schofield LR; Dobson RC; Jameson GB; Parker EJ
    J Mol Biol; 2014 Feb; 426(3):656-73. PubMed ID: 24239948
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.