These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 23768016)

  • 1. Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
    van Lierop BJ; Robinson SD; Kompella SN; Belgi A; McArthur JR; Hung A; MacRaild CA; Adams DJ; Norton RS; Robinson AJ
    ACS Chem Biol; 2013 Aug; 8(8):1815-21. PubMed ID: 23768016
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Scanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptor.
    Halai R; Clark RJ; Nevin ST; Jensen JE; Adams DJ; Craik DJ
    J Biol Chem; 2009 Jul; 284(30):20275-84. PubMed ID: 19447885
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analgesic alpha-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in rat sensory neurons via GABAB receptor activation.
    Callaghan B; Haythornthwaite A; Berecki G; Clark RJ; Craik DJ; Adams DJ
    J Neurosci; 2008 Oct; 28(43):10943-51. PubMed ID: 18945902
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets.
    Chhabra S; Belgi A; Bartels P; van Lierop BJ; Robinson SD; Kompella SN; Hung A; Callaghan BP; Adams DJ; Robinson AJ; Norton RS
    J Med Chem; 2014 Dec; 57(23):9933-44. PubMed ID: 25393758
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-Activity Studies Reveal the Molecular Basis for GABA
    Sadeghi M; Carstens BB; Callaghan BP; Daniel JT; Tae HS; O'Donnell T; Castro J; Brierley SM; Adams DJ; Craik DJ; Clark RJ
    ACS Chem Biol; 2018 Jun; 13(6):1577-1587. PubMed ID: 29746088
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1.
    Yu R; Seymour VA; Berecki G; Jia X; Akcan M; Adams DJ; Kaas Q; Craik DJ
    Sci Rep; 2015 Aug; 5():13264. PubMed ID: 26290113
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analgesic α-conotoxins Vc1.1 and RgIA inhibit N-type calcium channels in sensory neurons of α9 nicotinic receptor knockout mice.
    Callaghan B; Adams DJ
    Channels (Austin); 2010; 4(1):51-4. PubMed ID: 20368690
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels.
    Daly NL; Callaghan B; Clark RJ; Nevin ST; Adams DJ; Craik DJ
    J Biol Chem; 2011 Mar; 286(12):10233-7. PubMed ID: 21252227
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?
    Mohammadi SA; Christie MJ
    Toxins (Basel); 2015 Sep; 7(10):3916-32. PubMed ID: 26426047
    [TBL] [Abstract][Full Text] [Related]  

  • 10. α-Conotoxin Vc1.1 Structure-Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement.
    Chu X; Tae HS; Xu Q; Jiang T; Adams DJ; Yu R
    ACS Chem Neurosci; 2019 Oct; 10(10):4328-4336. PubMed ID: 31411453
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction of rat α9α10 nicotinic acetylcholine receptor with α-conotoxin RgIA and Vc1.1: Insights from docking, molecular dynamics and binding free energy contributions.
    Li R; Li X; Jiang J; Tian Y; Liu D; Zhangsun D; Fu Y; Wu Y; Luo S
    J Mol Graph Model; 2019 Nov; 92():55-64. PubMed ID: 31330438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors.
    Grishin AA; Cuny H; Hung A; Clark RJ; Brust A; Akondi K; Alewood PF; Craik DJ; Adams DJ
    J Biol Chem; 2013 Nov; 288(48):34428-42. PubMed ID: 24100032
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Are alpha9alpha10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?
    Nevin ST; Clark RJ; Klimis H; Christie MJ; Craik DJ; Adams DJ
    Mol Pharmacol; 2007 Dec; 72(6):1406-10. PubMed ID: 17804600
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor Subtype.
    Yu R; Tae HS; Tabassum N; Shi J; Jiang T; Adams DJ
    J Med Chem; 2018 May; 61(10):4628-4634. PubMed ID: 29733583
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting of N-Type Calcium Channels via GABA
    Cai F; Xu N; Liu Z; Ding R; Yu S; Dong M; Wang S; Shen J; Tae HS; Adams DJ; Zhang X; Dai Q
    J Med Chem; 2018 Nov; 61(22):10198-10205. PubMed ID: 30358401
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.
    Luo S; Zhangsun D; Harvey PJ; Kaas Q; Wu Y; Zhu X; Hu Y; Li X; Tsetlin VI; Christensen S; Romero HK; McIntyre M; Dowell C; Baxter JC; Elmslie KS; Craik DJ; McIntosh JM
    Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4026-35. PubMed ID: 26170295
    [TBL] [Abstract][Full Text] [Related]  

  • 17. αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors.
    Christensen SB; Bandyopadhyay PK; Olivera BM; McIntosh JM
    Biochem Pharmacol; 2015 Aug; 96(4):349-56. PubMed ID: 26074268
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The synthesis, structural characterization, and receptor specificity of the alpha-conotoxin Vc1.1.
    Clark RJ; Fischer H; Nevin ST; Adams DJ; Craik DJ
    J Biol Chem; 2006 Aug; 281(32):23254-63. PubMed ID: 16754662
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor.
    Halai R; Callaghan B; Daly NL; Clark RJ; Adams DJ; Craik DJ
    J Med Chem; 2011 Oct; 54(19):6984-92. PubMed ID: 21888386
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and activity of (2,8)-dicarba-(3,12)-cystino alpha-ImI, an alpha-conotoxin containing a nonreducible cystine analogue.
    MacRaild CA; Illesinghe J; van Lierop BJ; Townsend AL; Chebib M; Livett BG; Robinson AJ; Norton RS
    J Med Chem; 2009 Feb; 52(3):755-62. PubMed ID: 19125616
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.