BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 23768907)

  • 1. Structure-activity relationships of bisphenol A analogs at estrogen receptors (ERs): discovery of an ERα-selective antagonist.
    Maruyama K; Nakamura M; Tomoshige S; Sugita K; Makishima M; Hashimoto Y; Ishikawa M
    Bioorg Med Chem Lett; 2013 Jul; 23(14):4031-6. PubMed ID: 23768907
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bisphenol AF: Halogen bonding effect is a major driving force for the dual ERα-agonist and ERβ-antagonist activities.
    Liu X; Suyama K; Shiki J; Torikai K; Nose T; Shimohigashi M; Shimohigashi Y
    Bioorg Med Chem; 2020 Feb; 28(3):115274. PubMed ID: 31879182
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 3D models of MBP, a biologically active metabolite of bisphenol A, in human estrogen receptor α and estrogen receptor β.
    Baker ME; Chandsawangbhuwana C
    PLoS One; 2012; 7(10):e46078. PubMed ID: 23056236
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of natural estrogen receptor modulators with structure-based virtual screening.
    Cao X; Jiang J; Zhang S; Zhu L; Zou J; Diao Y; Xiao W; Shan L; Sun H; Zhang W; Huang J; Li H
    Bioorg Med Chem Lett; 2013 Jun; 23(11):3329-33. PubMed ID: 23608764
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ERα-agonist and ERβ-antagonist bifunctional next-generation bisphenols with no halogens: BPAP, BPB, and BPZ.
    Liu X; Matsuyama Y; Shimohigashi M; Shimohigashi Y
    Toxicol Lett; 2021 Jul; 345():24-33. PubMed ID: 33857583
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced estrogen receptor beta (ERβ) selectivity of fluorinated carborane-containing ER modulators.
    Ohta K; Ogawa T; Kaise A; Endo Y
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6555-8. PubMed ID: 24268550
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding.
    Liu X; Suyama K; Nose T; Shimohigashi M; Shimohigashi Y
    PLoS One; 2021; 16(2):e0246583. PubMed ID: 33561155
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bisphenol AF is a full agonist for the estrogen receptor ERalpha but a highly specific antagonist for ERbeta.
    Matsushima A; Liu X; Okada H; Shimohigashi M; Shimohigashi Y
    Environ Health Perspect; 2010 Sep; 118(9):1267-72. PubMed ID: 20427257
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design of a highly selective and potent class of non-planar estrogen receptor β agonists.
    Sundén H; Ma JN; Hansen LK; Gustavsson AL; Burstein ES; Olsson R
    ChemMedChem; 2013 Aug; 8(8):1283-94. PubMed ID: 23784708
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of ligand selectivity using reporter cell lines stably expressing estrogen receptor alpha or beta.
    Escande A; Pillon A; Servant N; Cravedi JP; Larrea F; Muhn P; Nicolas JC; Cavaillès V; Balaguer P
    Biochem Pharmacol; 2006 May; 71(10):1459-69. PubMed ID: 16554039
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular mechanism of action of bisphenol and bisphenol A mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells.
    Sengupta S; Obiorah I; Maximov PY; Curpan R; Jordan VC
    Br J Pharmacol; 2013 May; 169(1):167-78. PubMed ID: 23373633
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ER subtype selectivity of m-carborane-containing phenols: C-alkyl groups on the m-carborane cage enhance ERα selectivity.
    Ohta K; Ogawa T; Kato K; Oda A; Endo Y
    Bioorg Med Chem Lett; 2019 Aug; 29(16):2290-2293. PubMed ID: 31248773
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans.
    Takeuchi S; Shiraishi F; Kitamura S; Kuroki H; Jin K; Kojima H
    Toxicology; 2011 Nov; 289(2-3):112-21. PubMed ID: 21843587
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationship study of estrogen receptor down-regulators with a diphenylmethane skeleton.
    Nanjyo S; Ohgane K; Yoshioka H; Makishima M; Hashimoto Y; Noguchi-Yachide T
    Bioorg Med Chem; 2019 May; 27(10):1952-1961. PubMed ID: 30940565
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity.
    Compton DR; Sheng S; Carlson KE; Rebacz NA; Lee IY; Katzenellenbogen BS; Katzenellenbogen JA
    J Med Chem; 2004 Nov; 47(24):5872-93. PubMed ID: 15537344
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Estrogenic activity of bis(4-hydroxyphenyl)methanes with cyclic hydrophobic structure.
    Kojima T; Ogawa T; Kitao S; Sato M; Oda A; Ohta K; Endo Y
    Bioorg Med Chem; 2015 Nov; 23(21):6900-11. PubMed ID: 26462053
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of novel oestrogen receptor α agonists and antagonists by screening a revisited privileged structure moiety for nuclear receptors.
    Masuya T; Iwamoto M; Liu X; Matsushima A
    Sci Rep; 2019 Jul; 9(1):9954. PubMed ID: 31289329
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of an estrogen receptor beta-selective radioligand: 5-[18F]fluoro-(2R,3S)-2,3-bis(4-hydroxyphenyl)pentanenitrile and comparison of in vivo distribution with 16alpha-[18F]fluoro-17beta-estradiol.
    Yoo J; Dence CS; Sharp TL; Katzenellenbogen JA; Welch MJ
    J Med Chem; 2005 Oct; 48(20):6366-78. PubMed ID: 16190762
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands.
    Malamas MS; Manas ES; McDevitt RE; Gunawan I; Xu ZB; Collini MD; Miller CP; Dinh T; Henderson RA; Keith JC; Harris HA
    J Med Chem; 2004 Oct; 47(21):5021-40. PubMed ID: 15456246
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Symmetric 4,4'-(piperidin-4-ylidenemethylene)bisphenol derivatives as novel tunable estrogen receptor (ER) modulators.
    Sato M; Ohta K; Kaise A; Aoto S; Endo Y
    Bioorg Med Chem; 2016 Mar; 24(5):1089-94. PubMed ID: 26822566
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.