These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

688 related articles for article (PubMed ID: 23775842)

  • 21. The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
    Northcott PA; Fernandez-L A; Hagan JP; Ellison DW; Grajkowska W; Gillespie Y; Grundy R; Van Meter T; Rutka JT; Croce CM; Kenney AM; Taylor MD
    Cancer Res; 2009 Apr; 69(8):3249-55. PubMed ID: 19351822
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells.
    Hartmann W; Koch A; Brune H; Waha A; Schüller U; Dani I; Denkhaus D; Langmann W; Bode U; Wiestler OD; Schilling K; Pietsch T
    Am J Pathol; 2005 Apr; 166(4):1153-62. PubMed ID: 15793295
    [TBL] [Abstract][Full Text] [Related]  

  • 23. YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation.
    Fernandez-L A; Northcott PA; Dalton J; Fraga C; Ellison D; Angers S; Taylor MD; Kenney AM
    Genes Dev; 2009 Dec; 23(23):2729-41. PubMed ID: 19952108
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation.
    Tan IL; Wojcinski A; Rallapalli H; Lao Z; Sanghrajka RM; Stephen D; Volkova E; Korshunov A; Remke M; Taylor MD; Turnbull DH; Joyner AL
    Proc Natl Acad Sci U S A; 2018 Mar; 115(13):3392-3397. PubMed ID: 29531057
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis.
    Lin Z; Li S; Sheng H; Cai M; Ma LY; Hu L; Xu S; Yu LS; Zhang N
    J Cancer Res Clin Oncol; 2016 Dec; 142(12):2469-2478. PubMed ID: 27601167
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma.
    Tsiami F; Lago C; Pozza N; Piccioni F; Zhao X; Lülsberg F; Root DE; Tiberi L; Kool M; Schittenhelm J; Bandopadhayay P; Segal RA; Tabatabai G; Merk DJ
    Acta Neuropathol Commun; 2024 Aug; 12(1):125. PubMed ID: 39107797
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma.
    Pak E; MacKenzie EL; Zhao X; Pazyra-Murphy MF; Park PMC; Wu L; Shaw DL; Addleson EC; Cayer SS; Lopez BG; Agar NYR; Rubin LL; Qi J; Merk DJ; Segal RA
    Neuro Oncol; 2019 Sep; 21(9):1150-1163. PubMed ID: 31111916
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.
    Thomas WD; Chen J; Gao YR; Cheung B; Koach J; Sekyere E; Norris MD; Haber M; Ellis T; Wainwright B; Marshall GM
    Oncogene; 2009 Apr; 28(13):1605-15. PubMed ID: 19234491
    [TBL] [Abstract][Full Text] [Related]  

  • 29. IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma.
    Kunhiraman H; McSwain L; Shahab SW; Gershon TR; MacDonald TJ; Kenney AM
    Acta Neuropathol Commun; 2023 Apr; 11(1):62. PubMed ID: 37029430
    [TBL] [Abstract][Full Text] [Related]  

  • 30. β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.
    Miele E; Po A; Begalli F; Antonucci L; Mastronuzzi A; Marras CE; Carai A; Cucchi D; Abballe L; Besharat ZM; Catanzaro G; Infante P; Di Marcotullio L; Canettieri G; De Smaele E; Screpanti I; Locatelli F; Ferretti E
    BMC Cancer; 2017 Jul; 17(1):488. PubMed ID: 28716052
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness.
    Casas BS; Adolphe C; Lois P; Navarrete N; Solís N; Bustamante E; Gac P; Cabané P; Gallegos I; Wainwright BJ; Palma V
    Oncotarget; 2017 Oct; 8(48):84006-84018. PubMed ID: 29137400
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Transcriptional repressor REST drives lineage stage-specific chromatin compaction at
    Dobson THW; Tao RH; Swaminathan J; Maegawa S; Shaik S; Bravo-Alegria J; Sharma A; Kennis B; Yang Y; Callegari K; Haltom AR; Taylor P; Kogiso M; Qi L; Khatua S; Goldman S; Lulla RR; Fangusaro J; MacDonald TJ; Li XN; Hawkins C; Rajaram V; Gopalakrishnan V
    Sci Signal; 2019 Jan; 12(565):. PubMed ID: 30670636
    [TBL] [Abstract][Full Text] [Related]  

  • 33. LOXL1-AS1 contributes to metastasis in sonic-hedgehog medulloblastoma by promoting cancer stem-like phenotypes.
    Do AD; Wu KS; Chu SS; Giang LH; Lin YL; Chang CC; Wong TT; Hsieh CL; Sung SY
    J Exp Clin Cancer Res; 2024 Apr; 43(1):130. PubMed ID: 38689348
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Restore the brake on tumor progression.
    Gordon RE; Zhang L; Yang ZJ
    Biochem Pharmacol; 2017 Aug; 138():1-6. PubMed ID: 28389227
    [TBL] [Abstract][Full Text] [Related]  

  • 35. p53 Function Is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma.
    Wei Y; Maximov V; Morrissy SA; Taylor MD; Pallas DC; Kenney AM
    Mol Cancer Res; 2019 Jan; 17(1):186-198. PubMed ID: 30224541
    [TBL] [Abstract][Full Text] [Related]  

  • 36. SHH inhibitors for the treatment of medulloblastoma.
    Samkari A; White J; Packer R
    Expert Rev Neurother; 2015; 15(7):763-70. PubMed ID: 26027634
    [TBL] [Abstract][Full Text] [Related]  

  • 37. An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling.
    Wijaya J; Vo BT; Liu J; Xu B; Wu G; Wang Y; Peng J; Zhang J; Janke LJ; Orr BA; Yu J; Roussel MF; Schuetz JD
    Cancer Res; 2020 Apr; 80(7):1524-1537. PubMed ID: 31948942
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Overcoming resistance to Sonic Hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma.
    Pambid MR; Berns R; Adomat HH; Hu K; Triscott J; Maurer N; Zisman N; Ramaswamy V; Hawkins CE; Taylor MD; Dunham C; Guns E; Dunn SE
    Pediatr Blood Cancer; 2014 Jan; 61(1):107-15. PubMed ID: 23940083
    [TBL] [Abstract][Full Text] [Related]  

  • 39. WIP1 enhances tumor formation in a sonic hedgehog-dependent model of medulloblastoma.
    Doucette TA; Yang Y; Pedone C; Kim JY; Dubuc A; Northcott PD; Taylor MD; Fults DW; Rao G
    Neurosurgery; 2012 Apr; 70(4):1003-10; discussion 1010. PubMed ID: 22037313
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.
    Binning MJ; Niazi T; Pedone CA; Lal B; Eberhart CG; Kim KJ; Laterra J; Fults DW
    Cancer Res; 2008 Oct; 68(19):7838-45. PubMed ID: 18829539
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 35.