248 related articles for article (PubMed ID: 23782415)
1. G-quadruplex DNA as a molecular target for induced synthetic lethality in cancer cells.
McLuckie KI; Di Antonio M; Zecchini H; Xian J; Caldas C; Krippendorff BF; Tannahill D; Lowe C; Balasubramanian S
J Am Chem Soc; 2013 Jul; 135(26):9640-3. PubMed ID: 23782415
[TBL] [Abstract][Full Text] [Related]
2. Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.
Zimmer J; Tacconi EMC; Folio C; Badie S; Porru M; Klare K; Tumiati M; Markkanen E; Halder S; Ryan A; Jackson SP; Ramadan K; Kuznetsov SG; Biroccio A; Sale JE; Tarsounas M
Mol Cell; 2016 Feb; 61(3):449-460. PubMed ID: 26748828
[TBL] [Abstract][Full Text] [Related]
3. Anti-tumoural activity of the G-quadruplex ligand pyridostatin against BRCA1/2-deficient tumours.
Groelly FJ; Porru M; Zimmer J; Benainous H; De Visser Y; Kosova AA; Di Vito S; Serra V; Ryan A; Leonetti C; Bruna A; Biroccio A; Tarsounas M
EMBO Mol Med; 2022 Mar; 14(3):e14501. PubMed ID: 35107878
[TBL] [Abstract][Full Text] [Related]
4. Light-mediated in cell downregulation of G-quadruplex-containing genes using a photo-caged ligand.
Murat P; Gormally MV; Sanders D; Di Antonio M; Balasubramanian S
Chem Commun (Camb); 2013 Oct; 49(76):8453-5. PubMed ID: 23949446
[TBL] [Abstract][Full Text] [Related]
5. Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells.
Müller S; Sanders DA; Di Antonio M; Matsis S; Riou JF; Rodriguez R; Balasubramanian S
Org Biomol Chem; 2012 Aug; 10(32):6537-46. PubMed ID: 22790277
[TBL] [Abstract][Full Text] [Related]
6. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
Rodriguez R; Miller KM; Forment JV; Bradshaw CR; Nikan M; Britton S; Oelschlaegel T; Xhemalce B; Balasubramanian S; Jackson SP
Nat Chem Biol; 2012 Feb; 8(3):301-10. PubMed ID: 22306580
[TBL] [Abstract][Full Text] [Related]
7. Stabilization of G-quadruplex DNA and inhibition of Bcl-2 expression by a pyridostatin analog.
Feng Y; Yang D; Chen H; Cheng W; Wang L; Sun H; Tang Y
Bioorg Med Chem Lett; 2016 Apr; 26(7):1660-3. PubMed ID: 26923693
[TBL] [Abstract][Full Text] [Related]
8. Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
Musumeci D; Amato J; Zizza P; Platella C; Cosconati S; Cingolani C; Biroccio A; Novellino E; Randazzo A; Giancola C; Pagano B; Montesarchio D
Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1341-1352. PubMed ID: 28130159
[TBL] [Abstract][Full Text] [Related]
9. Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands.
Bossaert M; Pipier A; Riou JF; Noirot C; Nguyên LT; Serre RF; Bouchez O; Defrancq E; Calsou P; Britton S; Gomez D
Elife; 2021 Jun; 10():. PubMed ID: 34180392
[TBL] [Abstract][Full Text] [Related]
10. The G-quadruplex DNA stabilizing drug pyridostatin promotes DNA damage and downregulates transcription of Brca1 in neurons.
Moruno-Manchon JF; Koellhoffer EC; Gopakumar J; Hambarde S; Kim N; McCullough LD; Tsvetkov AS
Aging (Albany NY); 2017 Sep; 9(9):1957-1970. PubMed ID: 28904242
[TBL] [Abstract][Full Text] [Related]
11. Differential responses of neurons, astrocytes, and microglia to G-quadruplex stabilization.
Tabor N; Ngwa C; Mitteaux J; Meyer MD; Moruno-Manchon JF; Zhu L; Liu F; Monchaud D; McCullough LD; Tsvetkov AS
Aging (Albany NY); 2021 Jun; 13(12):15917-15941. PubMed ID: 34139671
[TBL] [Abstract][Full Text] [Related]
12. DNA double-strand breaks repair inhibitors potentiates the combined effect of VP-16 and CDDP in human colorectal adenocarcinoma (LoVo) cells.
Kopa P; Macieja A; Pastwa E; Majsterek I; Poplawski T
Mol Biol Rep; 2021 Jan; 48(1):709-720. PubMed ID: 33389482
[TBL] [Abstract][Full Text] [Related]
13. Identification of dual DNA-PK MDR1 inhibitors for the potentiation of cytotoxic drug activity.
Mould E; Berry P; Jamieson D; Hill C; Cano C; Tan N; Elliott S; Durkacz B; Newell D; Willmore E
Biochem Pharmacol; 2014 Mar; 88(1):58-65. PubMed ID: 24418411
[TBL] [Abstract][Full Text] [Related]
14. Oxidative probing of the G4 DNA structure induced in double-stranded DNA by molecular crowding or pyridostatin.
Beniaminov A; Chashchina G; Shchyolkina A; Kaluzhny D
Biochimie; 2021 Dec; 191():33-36. PubMed ID: 34418485
[TBL] [Abstract][Full Text] [Related]
15. Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441.
Zhao Y; Thomas HD; Batey MA; Cowell IG; Richardson CJ; Griffin RJ; Calvert AH; Newell DR; Smith GC; Curtin NJ
Cancer Res; 2006 May; 66(10):5354-62. PubMed ID: 16707462
[TBL] [Abstract][Full Text] [Related]
16. DNA repair protein RAD52 is required for protecting G-quadruplexes in mammalian cells.
Liu S; Wang Z; Shah SB; Chang CY; Ai M; Nguyen T; Xiang R; Wu X
J Biol Chem; 2023 Jan; 299(1):102770. PubMed ID: 36470428
[TBL] [Abstract][Full Text] [Related]
17. Molecular recognition of a carboxy pyridostatin toward G-quadruplex structures: Why does it prefer RNA?
Rocca R; Talarico C; Moraca F; Costa G; Romeo I; Ortuso F; Alcaro S; Artese A
Chem Biol Drug Des; 2017 Nov; 90(5):919-925. PubMed ID: 28459507
[TBL] [Abstract][Full Text] [Related]
18. Selective recognition of DNA parallel G-quadruplexes by 3,8a-disubstituted indolizinones.
Zhang JT; Wang LX; Yang FM; Yang L; Liu Y; Tang YL
Bioorg Med Chem; 2021 Jan; 29():115848. PubMed ID: 33189508
[TBL] [Abstract][Full Text] [Related]
19. Nontoxic concentration of DNA-PK inhibitor NU7441 radio-sensitizes lung tumor cells with little effect on double strand break repair.
Sunada S; Kanai H; Lee Y; Yasuda T; Hirakawa H; Liu C; Fujimori A; Uesaka M; Okayasu R
Cancer Sci; 2016 Sep; 107(9):1250-5. PubMed ID: 27341700
[TBL] [Abstract][Full Text] [Related]
20. Chlorambucil cytotoxicity in malignant B lymphocytes is synergistically increased by 2-(morpholin-4-yl)-benzo[h]chomen-4-one (NU7026)-mediated inhibition of DNA double-strand break repair via inhibition of DNA-dependent protein kinase.
Amrein L; Loignon M; Goulet AC; Dunn M; Jean-Claude B; Aloyz R; Panasci L
J Pharmacol Exp Ther; 2007 Jun; 321(3):848-55. PubMed ID: 17351105
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]