BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

354 related articles for article (PubMed ID: 23788656)

  • 1. Novel amino-carbonitrile-pyrazole identified in a small molecule screen activates wild-type and ΔF508 cystic fibrosis transmembrane conductance regulator in the absence of a cAMP agonist.
    Namkung W; Park J; Seo Y; Verkman AS
    Mol Pharmacol; 2013 Sep; 84(3):384-92. PubMed ID: 23788656
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DeltaF508 CFTR processing correction and activity in polarized airway and non-airway cell monolayers.
    Rowe SM; Pyle LC; Jurkevante A; Varga K; Collawn J; Sloane PA; Woodworth B; Mazur M; Fulton J; Fan L; Li Y; Fortenberry J; Sorscher EJ; Clancy JP
    Pulm Pharmacol Ther; 2010 Aug; 23(4):268-78. PubMed ID: 20226262
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endogenous surface expression of ΔF508-CFTR mediates cAMP-stimulated Cl(-) current in CFTR(ΔF508/ΔF508) pig thyroid epithelial cells.
    Li Y; Ganta S; Fong P
    Exp Physiol; 2012 Jan; 97(1):115-24. PubMed ID: 21948195
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Failure of cAMP agonists to activate rescued deltaF508 CFTR in CFBE41o- airway epithelial monolayers.
    Bebok Z; Collawn JF; Wakefield J; Parker W; Li Y; Varga K; Sorscher EJ; Clancy JP
    J Physiol; 2005 Dec; 569(Pt 2):601-15. PubMed ID: 16210354
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potentiation of ΔF508- and G551D-CFTR-Mediated Cl- Current by Novel Hydroxypyrazolines.
    Park J; Khloya P; Seo Y; Kumar S; Lee HK; Jeon DK; Jo S; Sharma PK; Namkung W
    PLoS One; 2016; 11(2):e0149131. PubMed ID: 26863533
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synergy-based small-molecule screen using a human lung epithelial cell line yields ΔF508-CFTR correctors that augment VX-809 maximal efficacy.
    Phuan PW; Veit G; Tan J; Roldan A; Finkbeiner WE; Lukacs GL; Verkman AS
    Mol Pharmacol; 2014 Jul; 86(1):42-51. PubMed ID: 24737137
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening.
    Ma T; Vetrivel L; Yang H; Pedemonte N; Zegarra-Moran O; Galietta LJ; Verkman AS
    J Biol Chem; 2002 Oct; 277(40):37235-41. PubMed ID: 12161441
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The cystic fibrosis transmembrane conductance regulator attenuates the endogenous Ca2+ activated Cl- conductance of Xenopus oocytes.
    Kunzelmann K; Mall M; Briel M; Hipper A; Nitschke R; Ricken S; Greger R
    Pflugers Arch; 1997 Dec; 435(1):178-81. PubMed ID: 9359918
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological modulation of ion transport across wild-type and DeltaF508 CFTR-expressing human bronchial epithelia.
    Devor DC; Bridges RJ; Pilewski JM
    Am J Physiol Cell Physiol; 2000 Aug; 279(2):C461-79. PubMed ID: 10913013
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tgf-β1 inhibits Cftr biogenesis and prevents functional rescue of ΔF508-Cftr in primary differentiated human bronchial epithelial cells.
    Snodgrass SM; Cihil KM; Cornuet PK; Myerburg MM; Swiatecka-Urban A
    PLoS One; 2013; 8(5):e63167. PubMed ID: 23671668
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of natural coumarin compounds that rescue defective DeltaF508-CFTR chloride channel gating.
    Xu LN; Na WL; Liu X; Hou SG; Lin S; Yang H; Ma TH
    Clin Exp Pharmacol Physiol; 2008 Aug; 35(8):878-83. PubMed ID: 18430055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.
    Zegarra-Moran O; Romio L; Folli C; Caci E; Becq F; Vierfond JM; Mettey Y; Cabrini G; Fanen P; Galietta LJ
    Br J Pharmacol; 2002 Oct; 137(4):504-12. PubMed ID: 12359632
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potentiators of Defective ΔF508-CFTR Gating that Do Not Interfere with Corrector Action.
    Phuan PW; Veit G; Tan JA; Finkbeiner WE; Lukacs GL; Verkman AS
    Mol Pharmacol; 2015 Oct; 88(4):791-9. PubMed ID: 26245207
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the cystic fibrosis transmembrane conductance regulator by the flavonoid quercetin: potential use as a biomarker of ΔF508 cystic fibrosis transmembrane conductance regulator rescue.
    Pyle LC; Fulton JC; Sloane PA; Backer K; Mazur M; Prasain J; Barnes S; Clancy JP; Rowe SM
    Am J Respir Cell Mol Biol; 2010 Nov; 43(5):607-16. PubMed ID: 20042712
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SLC26A9 is a constitutively active, CFTR-regulated anion conductance in human bronchial epithelia.
    Bertrand CA; Zhang R; Pilewski JM; Frizzell RA
    J Gen Physiol; 2009 Apr; 133(4):421-38. PubMed ID: 19289574
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of deltaF508 CFTR in a cystic fibrosis respiratory epithelial cell line by 4-phenylbutyrate, genistein and CPX.
    Andersson C; Roomans GM
    Eur Respir J; 2000 May; 15(5):937-41. PubMed ID: 10853862
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective activation of cystic fibrosis transmembrane conductance regulator Cl- and HCO3- conductances.
    Reddy MM; Quinton PM
    JOP; 2001 Jul; 2(4 Suppl):212-8. PubMed ID: 11875262
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rescue of DeltaF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules.
    Van Goor F; Straley KS; Cao D; González J; Hadida S; Hazlewood A; Joubran J; Knapp T; Makings LR; Miller M; Neuberger T; Olson E; Panchenko V; Rader J; Singh A; Stack JH; Tung R; Grootenhuis PD; Negulescu P
    Am J Physiol Lung Cell Mol Physiol; 2006 Jun; 290(6):L1117-30. PubMed ID: 16443646
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Spiperone, identified through compound screening, activates calcium-dependent chloride secretion in the airway.
    Liang L; MacDonald K; Schwiebert EM; Zeitlin PL; Guggino WB
    Am J Physiol Cell Physiol; 2009 Jan; 296(1):C131-41. PubMed ID: 18987251
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of protein kinase CK2 closes the CFTR Cl channel, but has no effect on the cystic fibrosis mutant deltaF508-CFTR.
    Treharne KJ; Xu Z; Chen JH; Best OG; Cassidy DM; Gruenert DC; Hegyi P; Gray MA; Sheppard DN; Kunzelmann K; Mehta A
    Cell Physiol Biochem; 2009; 24(5-6):347-60. PubMed ID: 19910675
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.