These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 23792349)

  • 21. Identification of the first trans-(3R,4R)- dimethyl-4-(3-hydroxyphenyl)piperidine derivative to possess highly potent and selective opioid kappa receptor antagonist activity.
    Thomas JB; Atkinson RN; Rothman RB; Fix SE; Mascarella SW; Vinson NA; Xu H; Dersch CM; Lu Y; Cantrell BE; Zimmerman DM; Carroll FI
    J Med Chem; 2001 Aug; 44(17):2687-90. PubMed ID: 11495579
    [TBL] [Abstract][Full Text] [Related]  

  • 22. How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the κ-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation.
    An X; Bai Q; Bing Z; Zhou S; Shi D; Liu H; Yao X
    ACS Chem Neurosci; 2019 Mar; 10(3):1575-1584. PubMed ID: 30372027
    [TBL] [Abstract][Full Text] [Related]  

  • 23. N-[
    Schmitt S; Delamare J; Tirel O; Fillesoye F; Dhilly M; Perrio C
    Nucl Med Biol; 2017 Jan; 44():50-61. PubMed ID: 27821345
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Comparative modeling of human kappa opioid receptor and docking analysis with the peptide YFa.
    Patra MC; Kumar K; Pasha S; Chopra M
    J Mol Graph Model; 2012 Mar; 33():44-51. PubMed ID: 22172315
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Importance of phenolic address groups in opioid kappa receptor selective antagonists.
    Thomas JB; Fix SE; Rothman RB; Mascarella SW; Dersch CM; Cantrell BE; Zimmerman DM; Carroll FI
    J Med Chem; 2004 Feb; 47(4):1070-3. PubMed ID: 14761209
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Nascent structure-activity relationship study of a diastereomeric series of kappa opioid receptor antagonists derived from CJ-15,208.
    Dolle RE; Michaut M; Martinez-Teipel B; Seida PR; Ajello CW; Muller AL; DeHaven RN; Carroll PJ
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3647-50. PubMed ID: 19464172
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Design of high affinity cyclic pentapeptide ligands for kappa-opioid receptors.
    Przydzial MJ; Pogozheva ID; Ho JC; Bosse KE; Sawyer E; Traynor JR; Mosberg HI
    J Pept Res; 2005 Nov; 66(5):255-62. PubMed ID: 16218993
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Novel opioid cyclic tetrapeptides: Trp isomers of CJ-15,208 exhibit distinct opioid receptor agonism and short-acting κ opioid receptor antagonism.
    Ross NC; Reilley KJ; Murray TF; Aldrich JV; McLaughlin JP
    Br J Pharmacol; 2012 Feb; 165(4b):1097-108. PubMed ID: 21671905
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Unexpected opioid activity profiles of analogues of the novel peptide kappa opioid receptor ligand CJ-15,208.
    Aldrich JV; Kulkarni SS; Senadheera SN; Ross NC; Reilley KJ; Eans SO; Ganno ML; Murray TF; McLaughlin JP
    ChemMedChem; 2011 Sep; 6(9):1739-45. PubMed ID: 21761566
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Prediction of the conformational requirements for binding to the kappa-opioid receptor and its subtypes. I. Novel alpha-helical cyclic peptides and their role in receptor selectivity.
    Collins N; Hruby VJ
    Biopolymers; 1994 Sep; 34(9):1231-41. PubMed ID: 7948735
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Molecular modeling on kappa opioid receptor and its interaction with nonpeptide kappa opioid agonists.
    Liu DX; Jiang HL; Shen JS; Zhu WL; Zhao L; Chen KX; Ji RY
    Zhongguo Yao Li Xue Bao; 1999 Feb; 20(2):131-6. PubMed ID: 10437159
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Complex of an active mu-opioid receptor with a cyclic peptide agonist modeled from experimental constraints.
    Fowler CB; Pogozheva ID; Lomize AL; LeVine H; Mosberg HI
    Biochemistry; 2004 Dec; 43(50):15796-810. PubMed ID: 15595835
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Identification of an opioid kappa receptor subtype-selective N-substituent for (+)-(3R,4R)-dimethyl-4-(3-hydroxyphenyl)piperidine.
    Thomas JB; Fall MJ; Cooper JB; Rothman RB; Mascarella SW; Xu H; Partilla JS; Dersch CM; McCullough KB; Cantrell BE; Zimmerman DM; Carroll FI
    J Med Chem; 1998 Dec; 41(26):5188-97. PubMed ID: 9857089
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification, structure-activity relationships and molecular modeling of potent triamine and piperazine opioid ligands.
    Yongye AB; Appel JR; Giulianotti MA; Dooley CT; Medina-Franco JL; Nefzi A; Houghten RA; Martínez-Mayorga K
    Bioorg Med Chem; 2009 Aug; 17(15):5583-97. PubMed ID: 19576786
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Biaryl piperidines as potent and selective delta opioid receptor ligands.
    Liras S; McHardy SF; Allen MP; Segelstein BE; Heck SD; Bryce DK; Schmidt AW; Vanase-Frawley M; Callegari E; McLean S
    Bioorg Med Chem Lett; 2010 Jan; 20(2):503-7. PubMed ID: 20015649
    [TBL] [Abstract][Full Text] [Related]  

  • 36. NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor.
    O'Connor C; White KL; Doncescu N; Didenko T; Roth BL; Czaplicki G; Stevens RC; Wüthrich K; Milon A
    Proc Natl Acad Sci U S A; 2015 Sep; 112(38):11852-7. PubMed ID: 26372966
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design and synthesis of highly potent and selective cyclic dynorphin A analogs. 2. New analogs.
    Kawasaki AM; Knapp RJ; Kramer TH; Walton A; Wire WS; Hashimoto S; Yamamura HI; Porreca F; Burks TF; Hruby VJ
    J Med Chem; 1993 Mar; 36(6):750-7. PubMed ID: 8096246
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Behavioral Pharmacology of Novel Kappa Opioid Receptor Antagonists in Rats.
    Page S; Mavrikaki MM; Lintz T; Puttick D; Roberts E; Rosen H; Carroll FI; Carlezon WA; Chartoff EH
    Int J Neuropsychopharmacol; 2019 Nov; 22(11):735-745. PubMed ID: 31613314
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structure-activity relationships of trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine antagonists for mu- and kappa-opioid receptors.
    Zimmerman DM; Leander JD; Cantrell BE; Reel JK; Snoddy J; Mendelsohn LG; Johnson BG; Mitch CH
    J Med Chem; 1993 Oct; 36(20):2833-41. PubMed ID: 8410998
    [TBL] [Abstract][Full Text] [Related]  

  • 40. 3D modeling, ligand binding and activation studies of the cloned mouse delta, mu; and kappa opioid receptors.
    Filizola M; Laakkonen L; Loew GH
    Protein Eng; 1999 Nov; 12(11):927-42. PubMed ID: 10585498
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.