332 related articles for article (PubMed ID: 23804703)
1. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling.
Li N; Xi Y; Tinsley HN; Gurpinar E; Gary BD; Zhu B; Li Y; Chen X; Keeton AB; Abadi AH; Moyer MP; Grizzle WE; Chang WC; Clapper ML; Piazza GA
Mol Cancer Ther; 2013 Sep; 12(9):1848-59. PubMed ID: 23804703
[TBL] [Abstract][Full Text] [Related]
2. A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity.
Whitt JD; Li N; Tinsley HN; Chen X; Zhang W; Li Y; Gary BD; Keeton AB; Xi Y; Abadi AH; Grizzle WE; Piazza GA
Cancer Prev Res (Phila); 2012 Jun; 5(6):822-33. PubMed ID: 22556201
[TBL] [Abstract][Full Text] [Related]
3. Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition.
Tinsley HN; Gary BD; Thaiparambil J; Li N; Lu W; Li Y; Maxuitenko YY; Keeton AB; Piazza GA
Cancer Prev Res (Phila); 2010 Oct; 3(10):1303-13. PubMed ID: 20876730
[TBL] [Abstract][Full Text] [Related]
4. Suppression of β-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10.
Li N; Chen X; Zhu B; Ramírez-Alcántara V; Canzoneri JC; Lee K; Sigler S; Gary B; Li Y; Zhang W; Moyer MP; Salter EA; Wierzbicki A; Keeton AB; Piazza GA
Oncotarget; 2015 Sep; 6(29):27403-15. PubMed ID: 26299804
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of PDE5 by sulindac sulfide selectively induces apoptosis and attenuates oncogenic Wnt/β-catenin-mediated transcription in human breast tumor cells.
Tinsley HN; Gary BD; Keeton AB; Lu W; Li Y; Piazza GA
Cancer Prev Res (Phila); 2011 Aug; 4(8):1275-84. PubMed ID: 21505183
[TBL] [Abstract][Full Text] [Related]
6. Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G.
Tinsley HN; Gary BD; Keeton AB; Zhang W; Abadi AH; Reynolds RC; Piazza GA
Mol Cancer Ther; 2009 Dec; 8(12):3331-40. PubMed ID: 19996273
[TBL] [Abstract][Full Text] [Related]
7. Essential role of the cGMP/PKG signaling pathway in regulating the proliferation and survival of human renal carcinoma cells.
Ren Y; Zheng J; Yao X; Weng G; Wu L
Int J Mol Med; 2014 Nov; 34(5):1430-8. PubMed ID: 25244411
[TBL] [Abstract][Full Text] [Related]
8. Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells.
Liu L; Li H; Underwood T; Lloyd M; David M; Sperl G; Pamukcu R; Thompson WJ
J Pharmacol Exp Ther; 2001 Nov; 299(2):583-92. PubMed ID: 11602670
[TBL] [Abstract][Full Text] [Related]
9. Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G.
Soh JW; Kazi JU; Li H; Thompson WJ; Weinstein IB
Mol Carcinog; 2008 Jul; 47(7):519-25. PubMed ID: 18163459
[TBL] [Abstract][Full Text] [Related]
10. Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells.
Deguchi A; Thompson WJ; Weinstein IB
Cancer Res; 2004 Jun; 64(11):3966-73. PubMed ID: 15173009
[TBL] [Abstract][Full Text] [Related]
11. PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/β-catenin transcription, cancer cell growth, and tumor immunity.
Piazza GA; Ward A; Chen X; Maxuitenko Y; Coley A; Aboelella NS; Buchsbaum DJ; Boyd MR; Keeton AB; Zhou G
Drug Discov Today; 2020 Aug; 25(8):1521-1527. PubMed ID: 32562844
[TBL] [Abstract][Full Text] [Related]
12. Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.
Thompson WJ; Piazza GA; Li H; Liu L; Fetter J; Zhu B; Sperl G; Ahnen D; Pamukcu R
Cancer Res; 2000 Jul; 60(13):3338-42. PubMed ID: 10910034
[TBL] [Abstract][Full Text] [Related]
13. Activation of cGMP/PKG/p65 signaling associated with PDE5-Is downregulates CCL5 secretion by CD8
Jin S; Xiang P; Liu J; Yang Y; Hu S; Sheng J; He Q; Yu W; Han W; Jin J; Peng J
Prostate; 2019 Jun; 79(8):909-919. PubMed ID: 30958912
[TBL] [Abstract][Full Text] [Related]
14. Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.
Pitari GM; Li T; Baksh RI; Waldman SA
Mol Cancer Ther; 2006 May; 5(5):1190-6. PubMed ID: 16731751
[TBL] [Abstract][Full Text] [Related]
15. Sildenafil inhibits hypoxia-induced transient receptor potential canonical protein expression in pulmonary arterial smooth muscle via cGMP-PKG-PPARγ axis.
Wang J; Yang K; Xu L; Zhang Y; Lai N; Jiang H; Zhang Y; Zhong N; Ran P; Lu W
Am J Respir Cell Mol Biol; 2013 Aug; 49(2):231-40. PubMed ID: 23526219
[TBL] [Abstract][Full Text] [Related]
16. Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions.
Wilson LS; Elbatarny HS; Crawley SW; Bennett BM; Maurice DH
Proc Natl Acad Sci U S A; 2008 Sep; 105(36):13650-5. PubMed ID: 18757735
[TBL] [Abstract][Full Text] [Related]
17. Novel Non-Cyclooxygenase Inhibitory Derivative of Sulindac Inhibits Breast Cancer Cell Growth In Vitro and Reduces Mammary Tumorigenesis in Rats.
Tinsley HN; Mathew B; Chen X; Maxuitenko YY; Li N; Lowe WM; Whitt JD; Zhang W; Gary BD; Keeton AB; Grizzle WE; Grubbs CJ; Reynolds RC; Piazza GA
Cancers (Basel); 2023 Jan; 15(3):. PubMed ID: 36765604
[TBL] [Abstract][Full Text] [Related]
18. Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways.
Rice PL; Peters SL; Beard KS; Ahnen DJ
Mol Cancer Ther; 2006 Mar; 5(3):746-54. PubMed ID: 16546990
[TBL] [Abstract][Full Text] [Related]
19. Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells.
Deguchi A; Xing SW; Shureiqi I; Yang P; Newman RA; Lippman SM; Feinmark SJ; Oehlen B; Weinstein IB
Cancer Res; 2005 Sep; 65(18):8442-7. PubMed ID: 16166323
[TBL] [Abstract][Full Text] [Related]
20. Distinct allostery induced in the cyclic GMP-binding, cyclic GMP-specific phosphodiesterase (PDE5) by cyclic GMP, sildenafil, and metal ions.
Biswas KH; Visweswariah SS
J Biol Chem; 2011 Mar; 286(10):8545-8554. PubMed ID: 21193396
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
