BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

979 related articles for article (PubMed ID: 23809146)

  • 1. Mechanism of dual specificity kinase activity of DYRK1A.
    Walte A; Rüben K; Birner-Gruenberger R; Preisinger C; Bamberg-Lemper S; Hilz N; Bracher F; Becker W
    FEBS J; 2013 Sep; 280(18):4495-511. PubMed ID: 23809146
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.
    Adayev T; Chen-Hwang MC; Murakami N; Lee E; Bolton DC; Hwang YW
    Biochemistry; 2007 Jun; 46(25):7614-24. PubMed ID: 17536841
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
    Göckler N; Jofre G; Papadopoulos C; Soppa U; Tejedor FJ; Becker W
    FEBS J; 2009 Nov; 276(21):6324-37. PubMed ID: 19796173
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of a domain that transiently converts class 2 DYRKs into intramolecular tyrosine kinases.
    Kinstrie R; Luebbering N; Miranda-Saavedra D; Sibbet G; Han J; Lochhead PA; Cleghon V
    Sci Signal; 2010 Mar; 3(111):ra16. PubMed ID: 20197545
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of tyrosine autophosphorylation on catalytic activity and subcellular localisation of homeodomain-interacting protein kinases (HIPK).
    van der Laden J; Soppa U; Becker W
    Cell Commun Signal; 2015 Jan; 13():3. PubMed ID: 25630557
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.
    Lochhead PA; Sibbet G; Morrice N; Cleghon V
    Cell; 2005 Jun; 121(6):925-36. PubMed ID: 15960979
    [TBL] [Abstract][Full Text] [Related]  

  • 7. dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila.
    Lochhead PA; Sibbet G; Kinstrie R; Cleghon T; Rylatt M; Morrison DK; Cleghon V
    Biochem J; 2003 Sep; 374(Pt 2):381-91. PubMed ID: 12786602
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.
    Himpel S; Panzer P; Eirmbter K; Czajkowska H; Sayed M; Packman LC; Blundell T; Kentrup H; Grötzinger J; Joost HG; Becker W
    Biochem J; 2001 Nov; 359(Pt 3):497-505. PubMed ID: 11672423
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding.
    Alvarez M; Altafaj X; Aranda S; de la Luna S
    Mol Biol Cell; 2007 Apr; 18(4):1167-78. PubMed ID: 17229891
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
    Soundararajan M; Roos AK; Savitsky P; Filippakopoulos P; Kettenbach AN; Olsen JV; Gerber SA; Eswaran J; Knapp S; Elkins JM
    Structure; 2013 Jun; 21(6):986-96. PubMed ID: 23665168
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine.
    Seifert A; Allan LA; Clarke PR
    FEBS J; 2008 Dec; 275(24):6268-80. PubMed ID: 19016842
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop.
    Saul VV; de la Vega L; Milanovic M; Krüger M; Braun T; Fritz-Wolf K; Becker K; Schmitz ML
    J Mol Cell Biol; 2013 Feb; 5(1):27-38. PubMed ID: 23000554
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional characterization of peanut serine/threonine/tyrosine protein kinase: molecular docking and inhibition kinetics with tyrosine kinase inhibitors.
    Rudrabhatla P; Rajasekharan R
    Biochemistry; 2004 Sep; 43(38):12123-32. PubMed ID: 15379551
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deep evolutionary conservation of an intramolecular protein kinase activation mechanism.
    Han J; Miranda-Saavedra D; Luebbering N; Singh A; Sibbet G; Ferguson MA; Cleghon V
    PLoS One; 2012; 7(1):e29702. PubMed ID: 22235329
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutational analysis of two residues in the DYRK homology box of the protein kinase DYRK1A.
    Widowati EW; Bamberg-Lemper S; Becker W
    BMC Res Notes; 2018 May; 11(1):297. PubMed ID: 29764512
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of Dyrk1A kinase activity by 14-3-3.
    Kim D; Won J; Shin DW; Kang J; Kim YJ; Choi SY; Hwang MK; Jeong BW; Kim GS; Joe CO; Chung SH; Song WJ
    Biochem Biophys Res Commun; 2004 Oct; 323(2):499-504. PubMed ID: 15369779
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The structure of a dual-specificity tyrosine phosphorylation-regulated kinase 1A-PKC412 complex reveals disulfide-bridge formation with the anomalous catalytic loop HRD(HCD) cysteine.
    Alexeeva M; Åberg E; Engh RA; Rothweiler U
    Acta Crystallogr D Biol Crystallogr; 2015 May; 71(Pt 5):1207-15. PubMed ID: 25945585
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Unusual function of the activation loop in the protein kinase DYRK1A.
    Wiechmann S; Czajkowska H; de Graaf K; Grötzinger J; Joost HG; Becker W
    Biochem Biophys Res Commun; 2003 Mar; 302(2):403-8. PubMed ID: 12604362
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CDPKs are dual-specificity protein kinases and tyrosine autophosphorylation attenuates kinase activity.
    Oh MH; Wu X; Kim HS; Harper JF; Zielinski RE; Clouse SD; Huber SC
    FEBS Lett; 2012 Nov; 586(23):4070-5. PubMed ID: 23079037
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity.
    Papadopoulos C; Arato K; Lilienthal E; Zerweck J; Schutkowski M; Chatain N; Müller-Newen G; Becker W; de la Luna S
    J Biol Chem; 2011 Feb; 286(7):5494-505. PubMed ID: 21127067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 49.