210 related articles for article (PubMed ID: 23809763)
1. Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.
Peng WC; de Lau W; Forneris F; Granneman JC; Huch M; Clevers H; Gros P
Cell Rep; 2013 Jun; 3(6):1885-92. PubMed ID: 23809763
[TBL] [Abstract][Full Text] [Related]
2. Structural basis for R-spondin recognition by LGR4/5/6 receptors.
Wang D; Huang B; Zhang S; Yu X; Wu W; Wang X
Genes Dev; 2013 Jun; 27(12):1339-44. PubMed ID: 23756652
[TBL] [Abstract][Full Text] [Related]
3. LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor.
Gong X; Carmon KS; Lin Q; Thomas A; Yi J; Liu Q
PLoS One; 2012; 7(5):e37137. PubMed ID: 22615920
[TBL] [Abstract][Full Text] [Related]
4. Crystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).
Xu JG; Huang C; Yang Z; Jin M; Fu P; Zhang N; Luo J; Li D; Liu M; Zhou Y; Zhu Y
J Biol Chem; 2015 Jan; 290(4):2455-65. PubMed ID: 25480784
[TBL] [Abstract][Full Text] [Related]
5. Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.
Park S; Cui J; Yu W; Wu L; Carmon KS; Liu QJ
J Biol Chem; 2018 Jun; 293(25):9759-9769. PubMed ID: 29752411
[TBL] [Abstract][Full Text] [Related]
6. Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling.
Peng WC; de Lau W; Madoori PK; Forneris F; Granneman JC; Clevers H; Gros P
PLoS One; 2013; 8(12):e83110. PubMed ID: 24349440
[TBL] [Abstract][Full Text] [Related]
7. Reconstitution of R-spondin:LGR4:ZNRF3 adult stem cell growth factor signaling complexes with recombinant proteins produced in Escherichia coli.
Moad HE; Pioszak AA
Biochemistry; 2013 Oct; 52(41):7295-304. PubMed ID: 24050775
[TBL] [Abstract][Full Text] [Related]
8. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
de Lau W; Barker N; Low TY; Koo BK; Li VS; Teunissen H; Kujala P; Haegebarth A; Peters PJ; van de Wetering M; Stange DE; van Es JE; Guardavaccaro D; Schasfoort RB; Mohri Y; Nishimori K; Mohammed S; Heck AJ; Clevers H
Nature; 2011 Jul; 476(7360):293-7. PubMed ID: 21727895
[TBL] [Abstract][Full Text] [Related]
9. Crystal structures of Lgr4 and its complex with R-spondin1.
Xu K; Xu Y; Rajashankar KR; Robev D; Nikolov DB
Structure; 2013 Sep; 21(9):1683-9. PubMed ID: 23891289
[TBL] [Abstract][Full Text] [Related]
10. The structural basis of R-spondin recognition by LGR5 and RNF43.
Chen PH; Chen X; Lin Z; Fang D; He X
Genes Dev; 2013 Jun; 27(12):1345-50. PubMed ID: 23756651
[TBL] [Abstract][Full Text] [Related]
11. The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength.
de Lau W; Peng WC; Gros P; Clevers H
Genes Dev; 2014 Feb; 28(4):305-16. PubMed ID: 24532711
[TBL] [Abstract][Full Text] [Related]
12. WNT Signaling Driven by R-spondin 1 and LGR6 in High-grade Serous Ovarian Cancer.
Lee S; Jun J; Kim WJ; Tamayo P; Howell SB
Anticancer Res; 2020 Nov; 40(11):6017-6028. PubMed ID: 33109540
[TBL] [Abstract][Full Text] [Related]
13. Exploiting the Receptor-Binding Domains of R-Spondin 1 to Target Leucine-Rich Repeat-Containin G-Coupled Protein Receptor 5-Expressing Stem Cells in Ovarian Cancer.
Wong C; Mulero MC; Barth EI; Wang K; Shang X; Tikle S; Rice C; Gately D; Howell SB
J Pharmacol Exp Ther; 2023 May; 385(2):95-105. PubMed ID: 36849411
[TBL] [Abstract][Full Text] [Related]
14. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.
Carmon KS; Gong X; Lin Q; Thomas A; Liu Q
Proc Natl Acad Sci U S A; 2011 Jul; 108(28):11452-7. PubMed ID: 21693646
[TBL] [Abstract][Full Text] [Related]
15. LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling.
Glinka A; Dolde C; Kirsch N; Huang YL; Kazanskaya O; Ingelfinger D; Boutros M; Cruciat CM; Niehrs C
EMBO Rep; 2011 Sep; 12(10):1055-61. PubMed ID: 21909076
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of R-spondin 2 in complex with the ectodomains of its receptors LGR5 and ZNRF3.
Zebisch M; Jones EY
J Struct Biol; 2015 Aug; 191(2):149-55. PubMed ID: 26123262
[TBL] [Abstract][Full Text] [Related]
17. LGR4 and its ligands, R-spondin 1 and R-spondin 3, regulate food intake in the hypothalamus of male rats.
Li JY; Chai B; Zhang W; Fritze DM; Zhang C; Mulholland MW
Endocrinology; 2014 Feb; 155(2):429-40. PubMed ID: 24280058
[TBL] [Abstract][Full Text] [Related]
18. Evidence of the Role of R-Spondin 1 and Its Receptor Lgr4 in the Transmission of Mechanical Stimuli to Biological Signals for Bone Formation.
Shi GX; Zheng XF; Zhu C; Li B; Wang YR; Jiang SD; Jiang LS
Int J Mol Sci; 2017 Mar; 18(3):. PubMed ID: 28272338
[TBL] [Abstract][Full Text] [Related]
19. Novel Insights into Gastric Cancer: Methylation of R-spondins and Regulation of LGR5 by SP1.
Wilhelm F; Simon E; Böger C; Behrens HM; Krüger S; Röcken C
Mol Cancer Res; 2017 Jun; 15(6):776-785. PubMed ID: 28219935
[TBL] [Abstract][Full Text] [Related]
20. Leucine-rich repeat-containing G-protein coupled receptor 5/GPR49 activates G12/13-Rho GTPase pathway.
Kwon MS; Park BO; Kim HM; Kim S
Mol Cells; 2013 Sep; 36(3):267-72. PubMed ID: 23912594
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
