BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

331 related articles for article (PubMed ID: 23810670)

  • 1. Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/imidazole polyamides targeting 5'-GCGC-3'.
    Han YW; Kashiwazaki G; Morinaga H; Matsumoto T; Hashiya K; Bando T; Harada Y; Sugiyama H
    Bioorg Med Chem; 2013 Sep; 21(17):5436-41. PubMed ID: 23810670
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rational design of specific binding hairpin Py-Im polyamides targeting human telomere sequences.
    Guo C; Kawamoto Y; Asamitsu S; Sawatani Y; Hashiya K; Bando T; Sugiyama H
    Bioorg Med Chem; 2015 Feb; 23(4):855-60. PubMed ID: 25614111
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA.
    Pilch DS; Poklar N; Baird EE; Dervan PB; Breslauer KJ
    Biochemistry; 1999 Feb; 38(7):2143-51. PubMed ID: 10026298
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Binding of hairpin pyrrole and imidazole polyamides to DNA: relationship between torsion angle and association rate constants.
    Han YW; Matsumoto T; Yokota H; Kashiwazaki G; Morinaga H; Hashiya K; Bando T; Harada Y; Sugiyama H
    Nucleic Acids Res; 2012 Dec; 40(22):11510-7. PubMed ID: 23042247
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Extending the language of DNA molecular recognition by polyamides: unexpected influence of imidazole and pyrrole arrangement on binding affinity and specificity.
    Buchmueller KL; Staples AM; Howard CM; Horick SM; Uthe PB; Le NM; Cox KK; Nguyen B; Pacheco KA; Wilson WD; Lee M
    J Am Chem Soc; 2005 Jan; 127(2):742-50. PubMed ID: 15643900
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit.
    Sawatani Y; Kashiwazaki G; Chandran A; Asamitsu S; Guo C; Sato S; Hashiya K; Bando T; Sugiyama H
    Bioorg Med Chem; 2016 Aug; 24(16):3603-11. PubMed ID: 27301681
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequence-specific DNA recognition by cyclic pyrrole-imidazole cysteine-derived polyamide dimers.
    Yamamoto M; Bando T; Morinaga H; Kawamoto Y; Hashiya K; Sugiyama H
    Chemistry; 2014 Jan; 20(3):752-9. PubMed ID: 24339258
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity.
    Westrate L; Mackay H; Brown T; Nguyen B; Kluza J; Wilson WD; Lee M; Hartley JA
    Biochemistry; 2009 Jun; 48(24):5679-88. PubMed ID: 19419200
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Orientation preferences of hairpin pyrrole-imidazole polyamides toward
    Sato S; Asamitsu S; Bando T; Sugiyama H
    Bioorg Med Chem; 2019 Jun; 27(11):2167-2171. PubMed ID: 31000407
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discrimination of hairpin polyamides with an alpha-substituted-gamma-aminobutyric acid as a 5'-TG-3' reader in DNA minor groove.
    Zhang W; Bando T; Sugiyama H
    J Am Chem Soc; 2006 Jul; 128(27):8766-76. PubMed ID: 16819870
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pyrrole-imidazole hairpin polyamides with high affinity at 5'-CGCG-3' DNA sequence; influence of cytosine methylation on binding.
    Minoshima M; Bando T; Sasaki S; Fujimoto J; Sugiyama H
    Nucleic Acids Res; 2008 May; 36(9):2889-94. PubMed ID: 18385159
    [TBL] [Abstract][Full Text] [Related]  

  • 12. On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides.
    White S; Baird EE; Dervan PB
    Chem Biol; 1997 Aug; 4(8):569-78. PubMed ID: 9281524
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sequence-specific DNA alkylation by tandem Py-Im polyamide conjugates.
    Taylor RD; Kawamoto Y; Hashiya K; Bando T; Sugiyama H
    Chem Asian J; 2014 Sep; 9(9):2527-33. PubMed ID: 24942204
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The application of fluorescence-conjugated pyrrole/imidazole polyamides in the characterization of protein-DNA complex formation.
    Han YW; Sugiyama H; Harada Y
    Biomater Sci; 2016 Mar; 4(3):391-9. PubMed ID: 26734690
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recognition of the DNA minor groove by pyrrole-imidazole polyamides: comparison of desmethyl- and N-methylpyrrole.
    Bremer RE; Szewczyk JW; Baird EE; Dervan PB
    Bioorg Med Chem; 2000 Aug; 8(8):1947-55. PubMed ID: 11003140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies.
    Mackay H; Brown T; Uthe PB; Westrate L; Sielaff A; Jones J; Lajiness JP; Kluza J; O'Hare C; Nguyen B; Davis Z; Bruce C; Wilson WD; Hartley JA; Lee M
    Bioorg Med Chem; 2008 Oct; 16(20):9145-53. PubMed ID: 18819814
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides.
    Bando T; Sugiyama H
    Acc Chem Res; 2006 Dec; 39(12):935-44. PubMed ID: 17176032
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sequence-specific gene silencing in mammalian cells by alkylating pyrrole-imidazole polyamides.
    Shinohara K; Narita A; Oyoshi T; Bando T; Teraoka H; Sugiyama H
    J Am Chem Soc; 2004 Apr; 126(16):5113-8. PubMed ID: 15099094
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Use of ferrocene scaffolds as pendant groups in hairpin-type pyrrole-imidazole polyamide molecules showing sequence-selective binding to DNA duplexes.
    Seio K; Mizuta M; Terada T; Sekine M
    J Org Chem; 2005 Dec; 70(25):10311-22. PubMed ID: 16323839
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element.
    Kageyama Y; Sugiyama H; Ayame H; Iwai A; Fujii Y; Huang LE; Kizaka-Kondoh S; Hiraoka M; Kihara K
    Acta Oncol; 2006; 45(3):317-24. PubMed ID: 16644575
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.