BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

561 related articles for article (PubMed ID: 23818614)

  • 1. Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.
    McCormack K; Santos S; Chapman ML; Krafte DS; Marron BE; West CW; Krambis MJ; Antonio BM; Zellmer SG; Printzenhoff D; Padilla KM; Lin Z; Wagoner PK; Swain NA; Stupple PA; de Groot M; Butt RP; Castle NA
    Proc Natl Acad Sci U S A; 2013 Jul; 110(29):E2724-32. PubMed ID: 23818614
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3.
    Leipold E; Hansel A; Borges A; Heinemann SH
    Mol Pharmacol; 2006 Jul; 70(1):340-7. PubMed ID: 16638971
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Selective Nav1.7 Inhibitor, PF-05089771, Interacts Equivalently with Fast and Slow Inactivated Nav1.7 Channels.
    Theile JW; Fuller MD; Chapman ML
    Mol Pharmacol; 2016 Nov; 90(5):540-548. PubMed ID: 27587537
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana.
    Liu Z; Cai T; Zhu Q; Deng M; Li J; Zhou X; Zhang F; Li D; Li J; Liu Y; Hu W; Liang S
    J Biol Chem; 2013 Jul; 288(28):20392-403. PubMed ID: 23703613
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biphasic voltage-dependent inactivation of human Na
    Godazgar M; Zhang Q; Chibalina MV; Rorsman P
    J Physiol; 2018 May; 596(9):1601-1626. PubMed ID: 29441586
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective Ligands and Drug Discovery Targeting the Voltage-Gated Sodium Channel Nav1.7.
    Payandeh J; Hackos DH
    Handb Exp Pharmacol; 2018; 246():271-306. PubMed ID: 29532179
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular surface of JZTX-V (β-Theraphotoxin-Cj2a) interacting with voltage-gated sodium channel subtype NaV1.4.
    Luo J; Zhang Y; Gong M; Lu S; Ma Y; Zeng X; Liang S
    Toxins (Basel); 2014 Jul; 6(7):2177-93. PubMed ID: 25055801
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Natural mutations change the affinity of μ-theraphotoxin-Hhn2a to voltage-gated sodium channels.
    Zhang F; Liu Y; Zhang C; Li J; Yang Z; Gong X; Gan Y; Chen P; Liu Z; Liang S
    Toxicon; 2015 Jan; 93():24-30. PubMed ID: 25447770
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation.
    Wang L; Zellmer SG; Printzenhoff DM; Castle NA
    Br J Pharmacol; 2015 Oct; 172(20):4905-18. PubMed ID: 26220736
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity.
    Wingerd JS; Mozar CA; Ussing CA; Murali SS; Chin YK; Cristofori-Armstrong B; Durek T; Gilchrist J; Vaughan CW; Bosmans F; Adams DJ; Lewis RJ; Alewood PF; Mobli M; Christie MJ; Rash LD
    Sci Rep; 2017 Apr; 7(1):974. PubMed ID: 28428547
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tetrodotoxin-sensitive α-subunits of voltage-gated sodium channels are relevant for inhibition of cardiac sodium currents by local anesthetics.
    Stoetzer C; Doll T; Stueber T; Herzog C; Echtermeyer F; Greulich F; Rudat C; Kispert A; Wegner F; Leffler A
    Naunyn Schmiedebergs Arch Pharmacol; 2016 Jun; 389(6):625-36. PubMed ID: 27000037
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacology of the Na
    Osteen JD; Sampson K; Iyer V; Julius D; Bosmans F
    Proc Natl Acad Sci U S A; 2017 Jun; 114(26):6836-6841. PubMed ID: 28607094
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The voltage-gated sodium channel inhibitor, 4,9-anhydrotetrodotoxin, blocks human Na
    Denomme N; Lukowski AL; Hull JM; Jameson MB; Bouza AA; Narayan ARH; Isom LL
    Neurosci Lett; 2020 Apr; 724():134853. PubMed ID: 32114117
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mapping the interaction site for the tarantula toxin hainantoxin-IV (β-TRTX-Hn2a) in the voltage sensor module of domain II of voltage-gated sodium channels.
    Cai T; Luo J; Meng E; Ding J; Liang S; Wang S; Liu Z
    Peptides; 2015 Jun; 68():148-56. PubMed ID: 25218973
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens.
    Cardoso FC; Dekan Z; Rosengren KJ; Erickson A; Vetter I; Deuis JR; Herzig V; Alewood PF; King GF; Lewis RJ
    Mol Pharmacol; 2015 Aug; 88(2):291-303. PubMed ID: 25979003
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PF-06526290 can both enhance and inhibit conduction through voltage-gated sodium channels.
    Wang L; Zellmer SG; Printzenhoff DM; Castle NA
    Br J Pharmacol; 2018 Jul; 175(14):2926-2939. PubMed ID: 29791744
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel Na
    Gilchrist JM; Yang ND; Jiang V; Moyer BD
    Mol Pharmacol; 2024 Feb; 105(3):233-249. PubMed ID: 38195157
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mapping of scorpion toxin receptor sites at voltage-gated sodium channels.
    Gurevitz M
    Toxicon; 2012 Sep; 60(4):502-11. PubMed ID: 22694883
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na
    Dvorak NM; Tapia CM; Singh AK; Baumgartner TJ; Wang P; Chen H; Wadsworth PA; Zhou J; Laezza F
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948337
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-throughput electrophysiological assays for voltage gated ion channels using SyncroPatch 768PE.
    Li T; Lu G; Chiang EY; Chernov-Rogan T; Grogan JL; Chen J
    PLoS One; 2017; 12(7):e0180154. PubMed ID: 28683073
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.