These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

536 related articles for article (PubMed ID: 23820376)

  • 1. E3 ubiquitin ligase Fbw7 negatively regulates granulocytic differentiation by targeting G-CSFR for degradation.
    Lochab S; Pal P; Kapoor I; Kanaujiya JK; Sanyal S; Behre G; Trivedi AK
    Biochim Biophys Acta; 2013 Dec; 1833(12):2639-2652. PubMed ID: 23820376
    [TBL] [Abstract][Full Text] [Related]  

  • 2. E6AP inhibits G-CSFR turnover and functions by promoting its ubiquitin-dependent proteasome degradation.
    Chhabra S; Kumar Y; Thacker G; Kapoor I; Lochab S; Sanyal S; Bhatt MLB; Chattopadhyay N; Trivedi AK
    Biochim Biophys Acta Mol Cell Res; 2017 Oct; 1864(10):1545-1553. PubMed ID: 28578910
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).
    Kannan MB; Dodard-Friedman I; Blank V
    J Biol Chem; 2015 Oct; 290(43):26292-302. PubMed ID: 26306035
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation.
    Zhao D; Zheng HQ; Zhou Z; Chen C
    Cancer Res; 2010 Jun; 70(11):4728-38. PubMed ID: 20484041
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ubiquitin Ligase, Fbw7, Targets CDX2 for Degradation via Two Phosphodegron Motifs in a GSK3β-Dependent Manner.
    Kumar Y; Shukla N; Thacker G; Kapoor I; Lochab S; Bhatt ML; Chattopadhyay N; Sanyal S; Trivedi AK
    Mol Cancer Res; 2016 Nov; 14(11):1097-1109. PubMed ID: 27470268
    [TBL] [Abstract][Full Text] [Related]  

  • 7. E3 Ubiquitin Ligase Fbw7 Negatively Regulates Osteoblast Differentiation by Targeting Runx2 for Degradation.
    Kumar Y; Kapoor I; Khan K; Thacker G; Khan MP; Shukla N; Kanaujiya JK; Sanyal S; Chattopadhyay N; Trivedi AK
    J Biol Chem; 2015 Dec; 290(52):30975-87. PubMed ID: 26542806
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis.
    Huang HL; Weng HY; Wang LQ; Yu CH; Huang QJ; Zhao PP; Wen JZ; Zhou H; Qu LH
    Mol Cancer Ther; 2012 May; 11(5):1155-65. PubMed ID: 22389469
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
    Kitagawa K; Hiramatsu Y; Uchida C; Isobe T; Hattori T; Oda T; Shibata K; Nakamura S; Kikuchi A; Kitagawa M
    Oncogene; 2009 Jun; 28(25):2393-405. PubMed ID: 19421138
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation.
    Wang R; Wang Y; Liu N; Ren C; Jiang C; Zhang K; Yu S; Chen Y; Tang H; Deng Q; Fu C; Wang Y; Li R; Liu M; Pan W; Wang P
    Cell Res; 2013 Jun; 23(6):803-19. PubMed ID: 23507969
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation.
    Wang J; Jo U; Joo SY; Kim H
    Oncotarget; 2016 Jun; 7(24):35724-35740. PubMed ID: 27232758
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A colon cancer-derived mutant of Krüppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3β (GSK3β) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7α (FBW7α).
    Bialkowska AB; Liu Y; Nandan MO; Yang VW
    J Biol Chem; 2014 Feb; 289(9):5997-6005. PubMed ID: 24398687
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.
    Liu N; Li H; Li S; Shen M; Xiao N; Chen Y; Wang Y; Wang W; Wang R; Wang Q; Sun J; Wang P
    J Biol Chem; 2010 Jun; 285(24):18858-67. PubMed ID: 20388706
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H; Shaik S; Onoyama I; Gao D; Tseng A; Maser RS; Zhai B; Wan L; Gutierrez A; Lau AW; Xiao Y; Christie AL; Aster J; Settleman J; Gygi SP; Kung AL; Look T; Nakayama KI; DePinho RA; Wei W
    Nature; 2011 Mar; 471(7336):104-9. PubMed ID: 21368833
    [TBL] [Abstract][Full Text] [Related]  

  • 15. E6AP, an E3 ubiquitin ligase negatively regulates granulopoiesis by targeting transcription factor C/EBPα for ubiquitin-mediated proteasome degradation.
    Pal P; Lochab S; Kanaujiya JK; Kapoor I; Sanyal S; Behre G; Trivedi AK
    Cell Death Dis; 2013 Apr; 4(4):e590. PubMed ID: 23598402
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.
    Trausch-Azar JS; Abed M; Orian A; Schwartz AL
    J Cell Physiol; 2015 Apr; 230(4):842-52. PubMed ID: 25204433
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia.
    Cassavaugh JM; Hale SA; Wellman TL; Howe AK; Wong C; Lounsbury KM
    J Cell Biochem; 2011 Dec; 112(12):3882-90. PubMed ID: 21964756
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The transcription factor STAT2 enhances proteasomal degradation of RCAN1 through the ubiquitin E3 ligase FBW7.
    Lee JW; Kang HS; Lee JY; Lee EJ; Rhim H; Yoon JH; Seo SR; Chung KC
    Biochem Biophys Res Commun; 2012 Apr; 420(2):404-10. PubMed ID: 22426484
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
    Welcker M; Orian A; Jin J; Grim JE; Harper JW; Eisenman RN; Clurman BE
    Proc Natl Acad Sci U S A; 2004 Jun; 101(24):9085-90. PubMed ID: 15150404
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FBW7 Inhibits Myeloid Differentiation in Acute Myeloid Leukemia via GSK3-Dependent Ubiquitination of PU.1.
    Mishra M; Thacker G; Sharma A; Singh AK; Upadhyay V; Sanyal S; Verma SP; Tripathi AK; Bhatt MLB; Trivedi AK
    Mol Cancer Res; 2021 Feb; 19(2):261-273. PubMed ID: 33188146
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.