195 related articles for article (PubMed ID: 23821410)
1. Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities.
Esposito F; Sanna C; Del Vecchio C; Cannas V; Venditti A; Corona A; Bianco A; Serrilli AM; Guarcini L; Parolin C; Ballero M; Tramontano E
Pathog Dis; 2013 Aug; 68(3):116-24. PubMed ID: 23821410
[TBL] [Abstract][Full Text] [Related]
2. Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6.
Corona A; Meleddu R; Esposito F; Distinto S; Bianco G; Masaoka T; Maccioni E; Menéndez-Arias L; Alcaro S; Le Grice SF; Tramontano E
PLoS One; 2016; 11(1):e0147225. PubMed ID: 26800261
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1,3-diones: dual inhibition against HIV reverse transcriptase-associated RNase H and polymerase with antiviral activities.
Vernekar SK; Liu Z; Nagy E; Miller L; Kirby KA; Wilson DJ; Kankanala J; Sarafianos SG; Parniak MA; Wang Z
J Med Chem; 2015 Jan; 58(2):651-64. PubMed ID: 25522204
[TBL] [Abstract][Full Text] [Related]
4. Cutting into the Substrate Dominance: Pharmacophore and Structure-Based Approaches toward Inhibiting Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H.
Wang L; Sarafianos SG; Wang Z
Acc Chem Res; 2020 Jan; 53(1):218-230. PubMed ID: 31880912
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone.
Borkow G; Fletcher RS; Barnard J; Arion D; Motakis D; Dmitrienko GI; Parniak MA
Biochemistry; 1997 Mar; 36(11):3179-85. PubMed ID: 9115994
[TBL] [Abstract][Full Text] [Related]
6. 6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro.
Tramontano E; Esposito F; Badas R; Di Santo R; Costi R; La Colla P
Antiviral Res; 2005 Feb; 65(2):117-24. PubMed ID: 15708638
[TBL] [Abstract][Full Text] [Related]
7. Exploiting drug-resistant enzymes as tools to identify thienopyrimidinone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.
Masaoka T; Chung S; Caboni P; Rausch JW; Wilson JA; Taskent-Sezgin H; Beutler JA; Tocco G; Le Grice SF
J Med Chem; 2013 Jul; 56(13):5436-45. PubMed ID: 23631411
[TBL] [Abstract][Full Text] [Related]
8. Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action.
Esposito F; Mandrone M; Del Vecchio C; Carli I; Distinto S; Corona A; Lianza M; Piano D; Tacchini M; Maccioni E; Cottiglia F; Saccon E; Poli F; Parolin C; Tramontano E
Pathog Dis; 2017 Aug; 75(6):. PubMed ID: 28637198
[TBL] [Abstract][Full Text] [Related]
9. Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity.
Suchaud V; Bailly F; Lion C; Tramontano E; Esposito F; Corona A; Christ F; Debyser Z; Cotelle P
Bioorg Med Chem Lett; 2012 Jun; 22(12):3988-92. PubMed ID: 22607675
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of human immunodeficiency virus type 1 reverse transcriptase, RNase H, and integrase activities by hydroxytropolones.
Didierjean J; Isel C; Querré F; Mouscadet JF; Aubertin AM; Valnot JY; Piettre SR; Marquet R
Antimicrob Agents Chemother; 2005 Dec; 49(12):4884-94. PubMed ID: 16304149
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H.
Kankanala J; Kirby KA; Huber AD; Casey MC; Wilson DJ; Sarafianos SG; Wang Z
Eur J Med Chem; 2017 Dec; 141():149-161. PubMed ID: 29031062
[TBL] [Abstract][Full Text] [Related]
12. Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication.
Sanna C; Scognamiglio M; Fiorentino A; Corona A; Graziani V; Caredda A; Cortis P; Montisci M; Ceresola ER; Canducci F; Poli F; Tramontano E; Esposito F
PLoS One; 2018; 13(3):e0195168. PubMed ID: 29601601
[TBL] [Abstract][Full Text] [Related]
13. Uvaria angolensis as a promising source of inhibitors of HIV-1 RT-associated RNA-dependent DNA polymerase and RNase H functions.
Ngoutane Mfopa A; Corona A; Eloh K; Tramontano E; Frau A; Boyom FF; Caboni P; Tocco G
Nat Prod Res; 2018 Mar; 32(6):640-647. PubMed ID: 28540745
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions.
Corona A; Onnis V; Deplano A; Bianco G; Demurtas M; Distinto S; Cheng YC; Alcaro S; Esposito F; Tramontano E
Pathog Dis; 2017 Aug; 75(6):. PubMed ID: 28859311
[TBL] [Abstract][Full Text] [Related]
15. Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors.
Esposito F; Sechi M; Pala N; Sanna A; Koneru PC; Kvaratskhelia M; Naesens L; Corona A; Grandi N; di Santo R; D'Amore VM; Di Leva FS; Novellino E; Cosconati S; Tramontano E
Antiviral Res; 2020 Feb; 174():104671. PubMed ID: 31812637
[TBL] [Abstract][Full Text] [Related]
16. Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication.
Esposito F; Carli I; Del Vecchio C; Xu L; Corona A; Grandi N; Piano D; Maccioni E; Distinto S; Parolin C; Tramontano E
Phytomedicine; 2016 Nov; 23(12):1383-1391. PubMed ID: 27765358
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of the DNA polymerase and RNase H activities of HIV-1 reverse transcriptase and HIV-1 replication by Brasenia schreberi (Junsai) and Petasites japonicus (Fuki) components.
Hisayoshi T; Shinomura M; Yokokawa K; Kuze I; Konishi A; Kawaji K; Kodama EN; Hata K; Takahashi S; Nirasawa S; Sakuda S; Yasukawa K
J Nat Med; 2015 Jul; 69(3):432-40. PubMed ID: 25663480
[TBL] [Abstract][Full Text] [Related]
18. 3-Hydroxypyrimidine-2,4-diones as Selective Active Site Inhibitors of HIV Reverse Transcriptase-Associated RNase H: Design, Synthesis, and Biochemical Evaluations.
Tang J; Liu F; Nagy E; Miller L; Kirby KA; Wilson DJ; Wu B; Sarafianos SG; Parniak MA; Wang Z
J Med Chem; 2016 Mar; 59(6):2648-59. PubMed ID: 26927866
[TBL] [Abstract][Full Text] [Related]
19. Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase.
Boyer PL; Smith SJ; Zhao XZ; Das K; Gruber K; Arnold E; Burke TR; Hughes SH
J Virol; 2018 Jul; 92(13):. PubMed ID: 29643235
[TBL] [Abstract][Full Text] [Related]
20. Drug targeting of HIV-1 RNA.DNA hybrid structures: thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication.
Li TK; Barbieri CM; Lin HC; Rabson AB; Yang G; Fan Y; Gaffney BL; Jones RA; Pilch DS
Biochemistry; 2004 Aug; 43(30):9732-42. PubMed ID: 15274628
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]