BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

376 related articles for article (PubMed ID: 23821540)

  • 1. Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism.
    Liu Y; Lopez-Santiago LF; Yuan Y; Jones JM; Zhang H; O'Malley HA; Patino GA; O'Brien JE; Rusconi R; Gupta A; Thompson RC; Natowicz MR; Meisler MH; Isom LL; Parent JM
    Ann Neurol; 2013 Jul; 74(1):128-39. PubMed ID: 23821540
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome.
    Rubinstein M; Westenbroek RE; Yu FH; Jones CJ; Scheuer T; Catterall WA
    Neurobiol Dis; 2015 Jan; 73():106-17. PubMed ID: 25281316
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons.
    Jiao J; Yang Y; Shi Y; Chen J; Gao R; Fan Y; Yao H; Liao W; Sun XF; Gao S
    Hum Mol Genet; 2013 Nov; 22(21):4241-52. PubMed ID: 23773995
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential effects on sodium current impairments by distinct SCN1A mutations in GABAergic neurons derived from Dravet syndrome patients.
    Kim HW; Quan Z; Kim YB; Cheong E; Kim HD; Cho M; Jang J; Yoo YR; Lee JS; Kim JH; Kim YI; Kim DS; Kang HC
    Brain Dev; 2018 Apr; 40(4):287-298. PubMed ID: 29295803
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome.
    Favero M; Sotuyo NP; Lopez E; Kearney JA; Goldberg EM
    J Neurosci; 2018 Sep; 38(36):7912-7927. PubMed ID: 30104343
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients.
    Sun Y; Paşca SP; Portmann T; Goold C; Worringer KA; Guan W; Chan KC; Gai H; Vogt D; Chen YJ; Mao R; Chan K; Rubenstein JL; Madison DV; Hallmayer J; Froehlich-Santino WM; Bernstein JA; Dolmetsch RE
    Elife; 2016 Jul; 5():. PubMed ID: 27458797
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Strain- and age-dependent hippocampal neuron sodium currents correlate with epilepsy severity in Dravet syndrome mice.
    Mistry AM; Thompson CH; Miller AR; Vanoye CG; George AL; Kearney JA
    Neurobiol Dis; 2014 May; 65():1-11. PubMed ID: 24434335
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Electrophysiological Alterations of Pyramidal Cells and Interneurons of the CA1 Region of the Hippocampus in a Novel Mouse Model of Dravet Syndrome.
    Dyment DA; Schock SC; Deloughery K; Tran MH; Ure K; Nutter LMJ; Creighton A; Yuan J; Banderali U; Comas T; Baumann E; Jezierski A; ; Boycott KM; Mackenzie AE; Martina M
    Genetics; 2020 Aug; 215(4):1055-1066. PubMed ID: 32554600
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome.
    Cheah CS; Yu FH; Westenbroek RE; Kalume FK; Oakley JC; Potter GB; Rubenstein JL; Catterall WA
    Proc Natl Acad Sci U S A; 2012 Sep; 109(36):14646-51. PubMed ID: 22908258
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Channelopathy as a SUDEP Biomarker in Dravet Syndrome Patient-Derived Cardiac Myocytes.
    Frasier CR; Zhang H; Offord J; Dang LT; Auerbach DS; Shi H; Chen C; Goldman AM; Eckhardt LL; Bezzerides VJ; Parent JM; Isom LL
    Stem Cell Reports; 2018 Sep; 11(3):626-634. PubMed ID: 30146492
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome.
    Kalume F; Oakley JC; Westenbroek RE; Gile J; de la Iglesia HO; Scheuer T; Catterall WA
    Neurobiol Dis; 2015 May; 77():141-54. PubMed ID: 25766678
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome.
    Tai C; Abe Y; Westenbroek RE; Scheuer T; Catterall WA
    Proc Natl Acad Sci U S A; 2014 Jul; 111(30):E3139-48. PubMed ID: 25024183
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcriptomes of Dravet syndrome iPSC derived GABAergic cells reveal dysregulated pathways for chromatin remodeling and neurodevelopment.
    Schuster J; Laan L; Klar J; Jin Z; Huss M; Korol S; Noraddin FH; Sobol M; Birnir B; Dahl N
    Neurobiol Dis; 2019 Dec; 132():104583. PubMed ID: 31445158
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Impairment of Sharp-Wave Ripples in a Murine Model of Dravet Syndrome.
    Cheah CS; Lundstrom BN; Catterall WA; Oakley JC
    J Neurosci; 2019 Nov; 39(46):9251-9260. PubMed ID: 31537705
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Generation of three human induced pluripotent stem cell (iPSC) lines from three patients with Dravet syndrome carrying distinct SCN1A gene mutations.
    Schuster J; Fatima A; Sobol M; Norradin FH; Laan L; Dahl N
    Stem Cell Res; 2019 Aug; 39():101523. PubMed ID: 31400703
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sexually Divergent Mortality and Partial Phenotypic Rescue After Gene Therapy in a Mouse Model of Dravet Syndrome.
    Niibori Y; Lee SJ; Minassian BA; Hampson DR
    Hum Gene Ther; 2020 Mar; 31(5-6):339-351. PubMed ID: 31830809
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A selective Na
    Chow CY; Chin YKY; Ma L; Undheim EAB; Herzig V; King GF
    Biochem Pharmacol; 2020 Nov; 181():113991. PubMed ID: 32335140
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development.
    Tsai MS; Lee ML; Chang CY; Fan HH; Yu IS; Chen YT; You JY; Chen CY; Chang FC; Hsiao JH; Khorkova O; Liou HH; Yanagawa Y; Lee LJ; Lin SW
    Neurobiol Dis; 2015 May; 77():35-48. PubMed ID: 25725421
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Unraveling Dravet Syndrome: Exploring the complex effects of sodium channel mutations on neuronal networks.
    Doorn N
    Sci Prog; 2024; 107(1):368504231225076. PubMed ID: 38373395
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antisense oligonucleotides restore excitability, GABA signalling and sodium current density in a Dravet syndrome model.
    Yuan Y; Lopez-Santiago L; Denomme N; Chen C; O'Malley HA; Hodges SL; Ji S; Han Z; Christiansen A; Isom LL
    Brain; 2024 Apr; 147(4):1231-1246. PubMed ID: 37812817
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.