BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

553 related articles for article (PubMed ID: 23831027)

  • 1. Prion-like properties of pathological TDP-43 aggregates from diseased brains.
    Nonaka T; Masuda-Suzukake M; Arai T; Hasegawa Y; Akatsu H; Obi T; Yoshida M; Murayama S; Mann DM; Akiyama H; Hasegawa M
    Cell Rep; 2013 Jul; 4(1):124-34. PubMed ID: 23831027
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells.
    Nonaka T; Arai T; Buratti E; Baralle FE; Akiyama H; Hasegawa M
    FEBS Lett; 2009 Jan; 583(2):394-400. PubMed ID: 19111550
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Intracellular seeded aggregation of TDP-43].
    Nonaka T; Hasegawa M
    Rinsho Shinkeigaku; 2012; 52(11):1056-8. PubMed ID: 23196514
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antibody against TDP-43 phosphorylated at serine 375 suggests conformational differences of TDP-43 aggregates among FTLD-TDP subtypes.
    Neumann M; Frick P; Paron F; Kosten J; Buratti E; Mackenzie IR
    Acta Neuropathol; 2020 Nov; 140(5):645-658. PubMed ID: 32778941
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disease-associated mutations of TDP-43 promote turnover of the protein through the proteasomal pathway.
    Araki W; Minegishi S; Motoki K; Kume H; Hohjoh H; Araki YM; Tamaoka A
    Mol Neurobiol; 2014 Dec; 50(3):1049-58. PubMed ID: 24477737
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy.
    Arai T; Hasegawa M; Nonoka T; Kametani F; Yamashita M; Hosokawa M; Niizato K; Tsuchiya K; Kobayashi Z; Ikeda K; Yoshida M; Onaya M; Fujishiro H; Akiyama H
    Neuropathology; 2010 Apr; 30(2):170-81. PubMed ID: 20102522
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A 43-kDa TDP-43 species is present in aggregates associated with frontotemporal lobar degeneration.
    Bosque PJ; Boyer PJ; Mishra P
    PLoS One; 2013; 8(5):e62301. PubMed ID: 23704877
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Hasegawa M; Arai T; Nonaka T; Kametani F; Yoshida M; Hashizume Y; Beach TG; Buratti E; Baralle F; Morita M; Nakano I; Oda T; Tsuchiya K; Akiyama H
    Ann Neurol; 2008 Jul; 64(1):60-70. PubMed ID: 18546284
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Arai T; Hasegawa M; Akiyama H; Ikeda K; Nonaka T; Mori H; Mann D; Tsuchiya K; Yoshida M; Hashizume Y; Oda T
    Biochem Biophys Res Commun; 2006 Dec; 351(3):602-11. PubMed ID: 17084815
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Neurodegenerative disorders and TDP-43].
    Nonaka T; Inukai Y; Arai T; Hasegawa M
    Brain Nerve; 2009 Feb; 61(2):161-6. PubMed ID: 19235466
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology.
    Lee YC; Huang WC; Lin JH; Kao TJ; Lin HC; Lee KH; Lin HC; Shen CJ; Chang WC; Huang CC
    J Biomed Sci; 2018 Nov; 25(1):76. PubMed ID: 30404641
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade.
    De Rossi P; Lewis AJ; Furrer J; De Vos L; Demeter T; Zbinden A; Zhong W; Wiersma VI; Scialo C; Weber J; Guo Z; Scaramuzza S; Di Fabrizio M; Böing C; Castaño-Díez D; Al-Amoudi A; Pérez-Berlanga M; Lashley T; Stahlberg H; Polymenidou M
    EMBO Rep; 2021 Dec; 22(12):e53877. PubMed ID: 34806807
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphorylated and aggregated TDP-43 with seeding properties are induced upon mutant Huntingtin (mHtt) polyglutamine expression in human cellular models.
    Coudert L; Nonaka T; Bernard E; Hasegawa M; Schaeffer L; Leblanc P
    Cell Mol Life Sci; 2019 Jul; 76(13):2615-2632. PubMed ID: 30863908
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies.
    Igaz LM; Kwong LK; Chen-Plotkin A; Winton MJ; Unger TL; Xu Y; Neumann M; Trojanowski JQ; Lee VM
    J Biol Chem; 2009 Mar; 284(13):8516-24. PubMed ID: 19164285
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct TDP-43 inclusion morphologies in frontotemporal lobar degeneration with and without amyotrophic lateral sclerosis.
    Tan RH; Yang Y; Kim WS; Dobson-Stone C; Kwok JB; Kiernan MC; Halliday GM
    Acta Neuropathol Commun; 2017 Oct; 5(1):76. PubMed ID: 29078806
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct pathways leading to TDP-43-induced cellular dysfunctions.
    Yamashita M; Nonaka T; Hirai S; Miwa A; Okado H; Arai T; Hosokawa M; Akiyama H; Hasegawa M
    Hum Mol Genet; 2014 Aug; 23(16):4345-56. PubMed ID: 24698978
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Igaz LM; Kwong LK; Xu Y; Truax AC; Uryu K; Neumann M; Clark CM; Elman LB; Miller BL; Grossman M; McCluskey LF; Trojanowski JQ; Lee VM
    Am J Pathol; 2008 Jul; 173(1):182-94. PubMed ID: 18535185
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Review: Prion-like mechanisms of transactive response DNA binding protein of 43 kDa (TDP-43) in amyotrophic lateral sclerosis (ALS).
    Smethurst P; Sidle KC; Hardy J
    Neuropathol Appl Neurobiol; 2015 Aug; 41(5):578-97. PubMed ID: 25487060
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
    Wils H; Kleinberger G; Janssens J; Pereson S; Joris G; Cuijt I; Smits V; Ceuterick-de Groote C; Van Broeckhoven C; Kumar-Singh S
    Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3858-63. PubMed ID: 20133711
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aggresome formation and liquid-liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 43.
    Watanabe S; Inami H; Oiwa K; Murata Y; Sakai S; Komine O; Sobue A; Iguchi Y; Katsuno M; Yamanaka K
    Cell Death Dis; 2020 Oct; 11(10):909. PubMed ID: 33097688
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.