BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 23831574)

  • 1. Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.
    Vascotto C; Lirussi L; Poletto M; Tiribelli M; Damiani D; Fabbro D; Damante G; Demple B; Colombo E; Tell G
    Oncogene; 2014 May; 33(22):2876-87. PubMed ID: 23831574
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins.
    Poletto M; Lirussi L; Wilson DM; Tell G
    Mol Biol Cell; 2014 May; 25(10):1641-52. PubMed ID: 24648491
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nucleophosmin interaction with APE1: Insights into DNA repair regulation.
    López DJ; de Blas A; Hurtado M; García-Alija M; Mentxaka J; de la Arada I; Urbaneja MA; Alonso-Mariño M; Bañuelos S
    DNA Repair (Amst); 2020 Apr; 88():102809. PubMed ID: 32092641
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties.
    Poletto M; Malfatti MC; Dorjsuren D; Scognamiglio PL; Marasco D; Vascotto C; Jadhav A; Maloney DJ; Wilson DM; Simeonov A; Tell G
    Mol Carcinog; 2016 May; 55(5):688-704. PubMed ID: 25865359
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.
    Nabbouh AI; Hleihel RS; Saliba JL; Karam MM; Hamie MH; Wu HJM; Berthier CP; Tawil NM; Bonnet PA; Deleuze-Masquefa C; El Hajj HA
    Cancer; 2017 May; 123(9):1662-1673. PubMed ID: 28055106
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cleavage of the APE1 N-Terminal Domain in Acute Myeloid Leukemia Cells Is Associated with Proteasomal Activity.
    Lirussi L; Antoniali G; Scognamiglio PL; Marasco D; Dalla E; D'Ambrosio C; Arena S; Scaloni A; Tell G
    Biomolecules; 2020 Mar; 10(4):. PubMed ID: 32244430
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NPM1c impedes CTCF functions through cytoplasmic mislocalization in acute myeloid leukemia.
    Wang AJ; Han Y; Jia N; Chen P; Minden MD
    Leukemia; 2020 May; 34(5):1278-1290. PubMed ID: 31831844
    [TBL] [Abstract][Full Text] [Related]  

  • 8. APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC.
    Malfatti MC; Gerratana L; Dalla E; Isola M; Damante G; Di Loreto C; Puglisi F; Tell G
    J Exp Clin Cancer Res; 2019 Jul; 38(1):309. PubMed ID: 31307523
    [TBL] [Abstract][Full Text] [Related]  

  • 9. EAPB0503, an Imidazoquinoxaline Derivative Modulates SENP3/ARF Mediated SUMOylation, and Induces NPM1c Degradation in NPM1 Mutant AML.
    Skayneh H; Jishi B; Hleihel R; Hamie M; El Hajj R; Deleuze-Masquefa C; Bonnet PA; El Sabban M; El Hajj H
    Int J Mol Sci; 2022 Mar; 23(7):. PubMed ID: 35408798
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells.
    Lirussi L; Antoniali G; Vascotto C; D'Ambrosio C; Poletto M; Romanello M; Marasco D; Leone M; Quadrifoglio F; Bhakat KK; Scaloni A; Tell G
    Mol Biol Cell; 2012 Oct; 23(20):4079-96. PubMed ID: 22918947
    [TBL] [Abstract][Full Text] [Related]  

  • 11. APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.
    Vascotto C; Fantini D; Romanello M; Cesaratto L; Deganuto M; Leonardi A; Radicella JP; Kelley MR; D'Ambrosio C; Scaloni A; Quadrifoglio F; Tell G
    Mol Cell Biol; 2009 Apr; 29(7):1834-54. PubMed ID: 19188445
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression and prognostic significance of APE1/Ref-1 and NPM1 proteins in high-grade ovarian serous cancer.
    Londero AP; Orsaria M; Tell G; Marzinotto S; Capodicasa V; Poletto M; Vascotto C; Sacco C; Mariuzzi L
    Am J Clin Pathol; 2014 Mar; 141(3):404-14. PubMed ID: 24515769
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nm23-H1 protein binds to APE1 at AP sites and stimulates AP endonuclease activity following ionizing radiation of the human lung cancer A549 cells.
    Zhang ZM; Yang XQ; Wang D; Wang G; Yang ZZ; Qing Y; Yang ZX; Li MX; Xiang DB
    Cell Biochem Biophys; 2011 Dec; 61(3):561-72. PubMed ID: 21769563
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications.
    Falini B; Bolli N; Liso A; Martelli MP; Mannucci R; Pileri S; Nicoletti I
    Leukemia; 2009 Oct; 23(10):1731-43. PubMed ID: 19516275
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conformational Rearrangements Regulating the DNA Repair Protein APE1.
    Komaniecka N; Porras M; Cairn L; Santas JA; Ferreiro N; Penedo JC; Bañuelos S
    Int J Mol Sci; 2022 Jul; 23(14):. PubMed ID: 35887361
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia.
    Zhu G; Luo H; Feng Y; Guryanova OA; Xu J; Chen S; Lai Q; Sharma A; Xu B; Zhao Z; Feng R; Ni H; Claxton D; Guo Y; Mesa RA; Qiu Y; Yang FC; Li W; Nimer SD; Huang S; Xu M
    Nat Commun; 2021 Mar; 12(1):1956. PubMed ID: 33782403
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel role for Gadd45α in base excision repair: modulation of APE1 activity by the direct interaction of Gadd45α with PCNA.
    Kim HL; Kim SU; Seo YR
    Biochem Biophys Res Commun; 2013 May; 434(2):185-90. PubMed ID: 23485469
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair.
    Sengupta S; Mantha AK; Song H; Roychoudhury S; Nath S; Ray S; Bhakat KK
    Oncotarget; 2016 Nov; 7(46):75197-75209. PubMed ID: 27655688
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1.
    Balusu R; Fiskus W; Rao R; Chong DG; Nalluri S; Mudunuru U; Ma H; Chen L; Venkannagari S; Ha K; Abhyankar S; Williams C; McGuirk J; Khoury HJ; Ustun C; Bhalla KN
    Blood; 2011 Sep; 118(11):3096-106. PubMed ID: 21719597
    [TBL] [Abstract][Full Text] [Related]  

  • 20. When the good go bad: Mutant NPM1 in acute myeloid leukemia.
    Kunchala P; Kuravi S; Jensen R; McGuirk J; Balusu R
    Blood Rev; 2018 May; 32(3):167-183. PubMed ID: 29157973
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.