BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 23838884)

  • 1. DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition.
    Chen N; Balasenthil S; Reuther J; Frayna A; Wang Y; Chandler DS; Abruzzo LV; Rashid A; Rodriguez J; Lozano G; Cao Y; Lokken E; Chen J; Frazier ML; Sahin AA; Wistuba II; Sen S; Lott ST; Killary AM
    Cancer Discov; 2013 Oct; 3(10):1172-89. PubMed ID: 23838884
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DEAR1, a novel tumor suppressor that regulates cell polarity and epithelial plasticity.
    Chen N; Balasenthil S; Reuther J; Killary AM
    Cancer Res; 2014 Oct; 74(20):5683-9. PubMed ID: 25261235
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer.
    Lott ST; Chen N; Chandler DS; Yang Q; Wang L; Rodriguez M; Xie H; Balasenthil S; Buchholz TA; Sahin AA; Chaung K; Zhang B; Olufemi SE; Chen J; Adams H; Band V; El-Naggar AK; Frazier ML; Keyomarsi K; Hunt KK; Sen S; Haffty B; Hewitt SM; Krahe R; Killary AM
    PLoS Med; 2009 May; 6(5):e1000068. PubMed ID: 19536326
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer.
    Quintás-Cardama A; Post SM; Solis LM; Xiong S; Yang P; Chen N; Wistuba II; Killary AM; Lozano G
    J Pathol; 2014 Sep; 234(1):108-19. PubMed ID: 24890125
    [TBL] [Abstract][Full Text] [Related]  

  • 5. JAK/STAT3 signaling is required for TGF-β-induced epithelial-mesenchymal transition in lung cancer cells.
    Liu RY; Zeng Y; Lei Z; Wang L; Yang H; Liu Z; Zhao J; Zhang HT
    Int J Oncol; 2014 May; 44(5):1643-51. PubMed ID: 24573038
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tumor suppressor DEAR1 regulates mammary epithelial cell fate and predicts early onset and metastasis in triple negative breast cancer.
    Le UQ; Chen N; Balasenthil S; Lurie E; Yang F; Liu S; Rubin L; Solis Soto LM; Raso MG; Batra H; Sahin AA; Wistuba II; Killary AM
    Sci Rep; 2022 Nov; 12(1):19504. PubMed ID: 36376460
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Curcumin and emodin down-regulate TGF-β signaling pathway in human cervical cancer cells.
    Thacker PC; Karunagaran D
    PLoS One; 2015; 10(3):e0120045. PubMed ID: 25786122
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elf5 inhibits TGF-β-driven epithelial-mesenchymal transition in prostate cancer by repressing SMAD3 activation.
    Yao B; Zhao J; Li Y; Li H; Hu Z; Pan P; Zhang Y; Du E; Liu R; Xu Y
    Prostate; 2015 Jun; 75(8):872-82. PubMed ID: 25728398
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Smad3-mediated recruitment of the methyltransferase SETDB1/ESET controls
    Du D; Katsuno Y; Meyer D; Budi EH; Chen SH; Koeppen H; Wang H; Akhurst RJ; Derynck R
    EMBO Rep; 2018 Jan; 19(1):135-155. PubMed ID: 29233829
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells.
    Boudreau HE; Casterline BW; Rada B; Korzeniowska A; Leto TL
    Free Radic Biol Med; 2012 Oct; 53(7):1489-99. PubMed ID: 22728268
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-β/SMAD signaling.
    Jiang HL; Sun HF; Gao SP; Li LD; Hu X; Wu J; Jin W
    Oncotarget; 2015 Jun; 6(18):16352-65. PubMed ID: 25970785
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Vasohibin-2 is required for epithelial-mesenchymal transition of ovarian cancer cells by modulating transforming growth factor-β signaling.
    Norita R; Suzuki Y; Furutani Y; Takahashi K; Yoshimatsu Y; Podyma-Inoue KA; Watabe T; Sato Y
    Cancer Sci; 2017 Mar; 108(3):419-426. PubMed ID: 28064471
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer.
    Liu TY; Chen J; Shang CL; Shen HW; Huang JM; Liang YC; Wang W; Zhao YH; Liu D; Shu M; Guo LY; Hu Z; Yao SZ
    J Exp Clin Cancer Res; 2016 Oct; 35(1):170. PubMed ID: 27793172
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ski prevents TGF-β-induced EMT and cell invasion by repressing SMAD-dependent signaling in non-small cell lung cancer.
    Yang H; Zhan L; Yang T; Wang L; Li C; Zhao J; Lei Z; Li X; Zhang HT
    Oncol Rep; 2015 Jul; 34(1):87-94. PubMed ID: 25955797
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.
    Vincent T; Neve EP; Johnson JR; Kukalev A; Rojo F; Albanell J; Pietras K; Virtanen I; Philipson L; Leopold PL; Crystal RG; de Herreros AG; Moustakas A; Pettersson RF; Fuxe J
    Nat Cell Biol; 2009 Aug; 11(8):943-50. PubMed ID: 19597490
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MYOCD and SMAD3/SMAD4 form a positive feedback loop and drive TGF-β-induced epithelial-mesenchymal transition in non-small cell lung cancer.
    Tong X; Wang S; Lei Z; Li C; Zhang C; Su Z; Liu X; Zhao J; Zhang HT
    Oncogene; 2020 Apr; 39(14):2890-2904. PubMed ID: 32029901
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Heterodimer formation by Oct4 and Smad3 differentially regulates epithelial-to-mesenchymal transition-associated factors in breast cancer progression.
    Mandal G; Biswas S; Roy Chowdhury S; Chatterjee A; Purohit S; Khamaru P; Chakraborty S; Mandal PK; Gupta A; de la Mare JA; Edkins AL; Bhattacharyya A
    Biochim Biophys Acta Mol Basis Dis; 2018 Jun; 1864(6 Pt A):2053-2066. PubMed ID: 29526821
    [TBL] [Abstract][Full Text] [Related]  

  • 18. KLF17 empowers TGF-β/Smad signaling by targeting Smad3-dependent pathway to suppress tumor growth and metastasis during cancer progression.
    Ali A; Zhang P; Liangfang Y; Wenshe S; Wang H; Lin X; Dai Y; Feng XH; Moses R; Wang D; Li X; Xiao J
    Cell Death Dis; 2015 Mar; 6(3):e1681. PubMed ID: 25766320
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma.
    Risolino M; Mandia N; Iavarone F; Dardaei L; Longobardi E; Fernandez S; Talotta F; Bianchi F; Pisati F; Spaggiari L; Harter PN; Mittelbronn M; Schulte D; Incoronato M; Di Fiore PP; Blasi F; Verde P
    Proc Natl Acad Sci U S A; 2014 Sep; 111(36):E3775-84. PubMed ID: 25157139
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kaempferol Suppresses Transforming Growth Factor-β1-Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Threonine-179.
    Jo E; Park SJ; Choi YS; Jeon WK; Kim BC
    Neoplasia; 2015 Jul; 17(7):525-37. PubMed ID: 26297431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.